Tag: John C. Lantis II

Surgical Debridement With a Scalpel

John C Lantis II

Hello, I’m John Lantis, vascular surgeon, and today I’d like to spend a little bit of time speaking to you about the benefits of debridement and some fundamentals of the technique. Very simple office-based debridement for the outpatient wound. The goals of debridement are to take away the skin edges that would be hyperkeratotic, which would be around the edges. Those cells are actually cells that usually don’t even know how to migrate across the wound bed and need to be removed. But one also doesn’t want to forget the base of the wound, where at the base of the wound you would have increased bacterial burden and cells, if they’re present, that are very senescent or quiescent, and that they’re not able to turn over. So there are various ways of debriding and methods, but we’re going to be talking about sharp debridement today, specifically. Sharp debridement you want to have a rounded blade; using an 11 blade … read more

Evaluating the Effect of Omega-3–rich Fish Skin in the Treatment of Chronic, Nonresponsive …

Diabetic Foot Ulcers: Penultimate Analysis of a Multicenter, Prospective, Randomized Controlled Trial

Eric J. Lullove, Brock Liden, Patrick McEneaney, Allen Raphael, Robert Klein, Christopher Winters, John C Lantis II

This is the second of 3 planned articles reporting on a prospective, multicenter, randomized controlled trial assessing the efficacy of fish skin graft in the management of diabetic foot ulcers in comparison with the standard of care (collagen alginate dressing). Materials and Methods. The primary end point of this prospective randomized trial is the number of closed wounds at 12 weeks. Results. As of the time of this writing, 94 patients had completed the protocol. At 12-week follow-up, healing was achieved in 63.0% of index ulcers (29 of 46 patients) in the acellular fish skin graft group compared with 31.3% in the control group (15 of 48 patients) (P =.0036). In both groups, the mean time to healing was 7 weeks. The median number of applications of the fish skin graft to achieve healing was 6. Conclusion. A clinically and statistically significant difference in healing was observed between patients treated with acellular fish skin graft and those treated with a collagen … read more

BOVINE DERMAL SCAFFOLDS – JWC Masterclass

Diabetic foot ulcers can be extremely challenging to treat and are associated with a high
morbidity and mortality … A recent large randomised controlled trial (RCT), found that a single application of a fetal bovine acellular dermal matrix in combination with standard of care (SOC) is a faster and more effective treatment for these ulcers than SOC alone* … In this masterclass, the RCT investigators will discuss the evidence, and explore the implications for practice with other clinicians who have used the dermal scaffold. The debate will focus on how to optimise the use of this technology on this wound type … read more