Month: June 2025

New ACLM Guideline Prioritizes Lifestyle Interventions in Type 2 Diabetes Care

On June 10, 2025, the American College of Lifestyle Medicine released its first clinical practice guideline explicitly placing lifestyle behavior interventions at the center of adult type 2 diabetes and prediabetes management. Published in the *American Journal of Lifestyle Medicine*, this guideline offers practical tools and frameworks for lasting behavior change.

Key Highlights:

• Six Core Pillars: The guideline emphasizes plant-based nutrition, physical activity, restorative sleep, stress management, social connection, and avoidance of harmful substances (tobacco and alcohol).
• Actionable Strategies: Clinicians are guided to assess baseline habits, coach using SMART goals, evaluate readiness for change, and support medication de-escalation when lifestyle change is effective.
• Broad Endorsements: Backed by major organizations—including AACE, AANP, AND, and ADCES—the guideline shifts lifestyle from adjunctive advice to primary therapy.
• Goal of Remission: Emphasizes achieving not just management but remission of type 2 diabetes—defined as normoglycemia without glucose-lowering therapy.
• Practical Tools Included: Includes over 25 clinician and patient handouts, workflows, and behavior-change aids to support implementation in real-world care settings.

This guideline marks a paradigm shift—transforming lifestyle from secondary support into the main therapeutic approach for prediabetes and type 2 diabetes, while complementing existing pharmacologic and procedural strategies.

Source: American College of Lifestyle Medicine clinical guideline, June 10, 2025.

Keywords: type 2 diabetes, lifestyle medicine, diabetes remission, SMART goals, plant‑based nutrition

Read more on News-Medical.net

Efficacy of Cytoreg in the Treatment of Diabetic Foot Disease

A compassionate-use study evaluated Cytoreg—an investigational aqueous acid blend—administered orally and topically to patients with diabetic foot ulcers (DFUs) over 30 days.

Key Highlights:

• Study Design: Ten patients participated. All received oral Cytoreg; five also received weekly topical washes. Wound progress was tracked using the Saint Elian scoring system.
• Healing Outcomes: In the oral + topical group, 4 of 5 patients achieved complete healing; the fifth lost necrotic tissue. In the oral-only group, 2 of 4 achieved complete healing.
• Systemic Effects: Both groups showed significant rises in arterial hemoglobin and arterial oxygen partial pressure, along with reductions in HbA1c, liver enzymes, creatinine, and urea levels.
• Safety & Justification: No major adverse events were noted. Findings support the need for larger, controlled trials.

This preliminary study highlights Cytoreg’s potential to accelerate DFU closure and improve systemic laboratory markers—particularly when combined with topical application. However, randomized controlled trials are needed to validate efficacy and safety.

Based on Carrillo et al., “Efficacy of Cytoreg in the Treatment of Diabetic Foot Disease,” Journal of Wound Care (December 2024).

Keywords: Cytoreg, diabetic foot ulcer, Saint Elian system, acid therapy, systemic oxygen

Read the full article on Wound Central

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🔬 Spotlight: Acid-Based Therapies & Oxygen-Enhancing Adjuncts for DFUs

With Cytoreg showing promise as both an oral and topical treatment for diabetic foot ulcers, clinicians may look to similar agents that modulate tissue pH, promote oxygen delivery, or support wound debridement and granulation through biochemical means.

• Granudacyn® (Mölnlycke): A hypochlorous-acid–based wound irrigation solution and gel. Offers antimicrobial action while supporting moist wound healing. Safe for long-term use and ideal for DFUs at risk of infection.
• UrgoClean Ag® (Urgo Medical): Though not acid-based, this silver-reinforced fiber dressing helps modulate local bioburden and create a favorable wound pH microenvironment for DFU healing.
• Topical Oxygen Therapy (e.g., NATROX®, Epiflo®): These devices deliver low-flow oxygen directly to the wound bed, enhancing angiogenesis and collagen synthesis. Similar to the systemic oxygenation improvements seen with Cytoreg in early studies.
• pH-modulating gels (e.g., Wound pHarma prototypes): Still investigational, these are designed to shift chronic wound pH from alkaline to mildly acidic, restoring protease activity balance and promoting granulation.
• Hydrochlorous Acid Sprays (e.g., Vashe®, Puracyn®): Used for wound cleansing and inflammation control. While not systemic, their acidic pH and antimicrobial profile support wound bed preparation—especially in biofilm-laden DFUs.

Adjuncts that influence the wound’s chemical microenvironment—either through pH, oxygenation, or targeted biochemical pathways—are increasingly seen as critical tools alongside debridement and systemic support in diabetic foot ulcer management. Cytoreg’s dual administration model is an emerging concept worth watching as trials expand.

Pig’s Toenail Egg Yolk Ointment Promotes Pressure Ulcer Healing via PI3K‑Akt Pathway

A randomized controlled trial published in *International Journal of Lower Extremity Wounds* (June 2025) evaluated a novel traditional medicine—pig’s toenail egg yolk ointment—against standard wound dressings in stage III–IV pressure ulcers. The study also explored its biological mechanism in an animal model.

Key Highlights:

• Clinical Benefits: In 80 patients, those treated with the ointment achieved significantly better outcomes, including lower PUSH scores, faster wound healing, and reduced dressing costs compared to controls.
• Enhanced Angiogenesis: Rats treated with the ointment showed accelerated ulcer closure, increased blood vessel growth, and reduced inflammatory infiltration.
• Molecular Mechanism: Treatment activated the PI3K-Akt signaling pathway—evidenced by increased phosphorylated PI3K and Akt—and elevated VEGF levels, while decreasing pro-inflammatory cytokines TNF-α and IL-1β.
• Dual Action: The ointment appears to simultaneously promote neovascularization and modulate inflammation, offering a combined pathway to improved healing.

This study suggests pig’s toenail egg yolk ointment may offer a cost-effective, mechanism-based alternative for managing severe pressure ulcers—pending further trials to confirm safety, consistency, and scalability.

Based on Jiansheng Shao et al., “Pig’s Toenail Egg Yolk Ointment Promotes Pressure Ulcer Healing via the PI3K-Akt Pathway,” *Int J Low Extrem Wounds*, June 2025.

Keywords: PI3K‑Akt pathway, pressure ulcer treatment, angiogenesis, inflammation modulation, traditional medicine

Read the full study on PubMed

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🔬 Spotlight: Bioactive Topicals Targeting Angiogenesis and Inflammation

As pressure ulcer research explores natural and molecularly active treatments, several commercial and investigational agents aim to mimic or enhance similar healing pathways—especially those involving the PI3K‑Akt axis and VEGF-driven angiogenesis.

• Medihoney® (Derma Sciences): A medical-grade honey dressing known to support angiogenesis and reduce inflammation. Used in chronic wounds including pressure ulcers and diabetic foot ulcers.
• Epiflo® (Ogenix): A continuous-flow topical oxygen therapy that stimulates angiogenesis through hypoxia-inducible factors, indirectly affecting PI3K/Akt and VEGF expression.
• Becaplermin gel (Regranex®): A recombinant human platelet-derived growth factor (rhPDGF) that directly promotes angiogenesis and fibroblast recruitment in diabetic ulcers. Though not directly PI3K-targeting, its mechanism overlaps via downstream effects.
• Amniotic Membrane Extracts (e.g., Grafix®, EpiFix®): These biologics contain growth factors including VEGF, EGF, and bFGF that support tissue regeneration, epithelialization, and neovascularization.
• Curcumin-based topicals: Found in some experimental or compounded preparations, curcumin may suppress inflammatory cytokines and activate Akt signaling, though more clinical validation is needed.

Topical agents that modulate key healing pathways—especially those targeting both vascularization and cytokine control—offer exciting adjuncts to traditional wound care. While pig’s toenail egg yolk ointment is not yet commercially available, it reflects a broader trend toward harnessing bioactive formulations with dual molecular action.

3D Acellular Collagen Matrix Shows Promise in Deep/Tunneling Diabetic Foot Ulcers

A retrospective case series published in *Journal of Wound Care* (Sept 2024) evaluated the use of a three-dimensional acellular collagen matrix (3D‑ACM) to treat deep, tunneling, or undermining diabetic foot ulcers (DFUs), which standard flat matrices cannot adequately fill.

Key Highlights:

• Patient Group: 11 patients with 13 deep or tunneling DFUs (average depth 1.6 cm); all wounds present ≥4 weeks.
• Rapid Early Response: 62% of wounds achieved ≥50% closure within 4 weeks.
• Healing Outcomes: 54% of wounds fully closed by 12 weeks; the remainder healed between 12–22 weeks. Overall mean therapy time was ~13 weeks.
• Matrix Benefits: The 3D structure enabled wound-wall apposition, creating a protective, biocompatible scaffold to facilitate cell migration and granulation in complex cavities.

This small series indicates that conforming 3D matrices may offer a valuable option for deep or irregular DFUs, though healing timelines vary with wound depth and volume. Further controlled research is needed to confirm efficacy and cost-effectiveness.

Based on Abdo RJ & Couch AL. “Use of three-dimensional acellular collagen matrix in deep or tunnelling diabetic foot ulcers: a retrospective case series,” *J Wound Care*, 2024.

Keywords: 3D acellular collagen matrix, diabetic foot ulcer, tunneling ulcer, deep ulcer, wound matrix

Read the full article on Journal of Wound Care

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🔬 Spotlight: Commercial 3D/Collagen Matrix Products

Enhanced scaffolds offer targeted wound-bed filling with biocompatible structure—especially useful for deep, tunneling, or undermining wounds.

• Integra Bilayer Wound Matrix – A porous, cross‑linked bovine-tendon collagen–glycosaminoglycan dermal substitute topped with a silicone layer. Designed to fill irregular wound beds and support neodermis formation. Highly regarded in DFU management for its scaffold properties.

• Promogran Prisma Matrix (ORC‑Collagen) – A freeze-dried collagen and oxidized regenerated cellulose matrix that adapts to wound shape, absorbs excess fluid, and promotes granulation. Available in sheets and rope formats to accommodate deep tunnels.

• Oasis Fenestrated Wound Matrix – A 3D porcine SIS-derived acellular matrix with fenestrations for flexibility and drainage. Supports cellular ingrowth and structural integration in complex wound geometries.

• Smith & Nephew BIOSTEP Collagen Matrix – A conformable collagen matrix dressing that provides a moist, enzyme-modulating environment, ideal for covering wound beds and supporting epithelial migration.

Hypergranulation (“Proud Flesh”): Understanding, Causes & Management

Hypergranulation—often referred to as “proud flesh”—is a common complication in wound healing where granulation tissue grows excessively above the wound bed. While initially part of the normal repair process, this overgrowth can inhibit epithelialization and delay closure, especially in wounds healing by secondary intention.

Key Highlights:

• Definition & Appearance: Hypergranulation presents as shiny, moist, and often raspberry-like tissue that protrudes beyond the skin surface. It is typically friable and may bleed easily when touched.
• Common Triggers: Factors include prolonged inflammation, bacterial colonization (e.g., Pseudomonas), trauma from medical devices (drains, catheters), chronic edema, fingertip injuries, or idiopathic causes.
• Impact on Healing: Although granulation is essential in wound repair, overgrowth that surpasses skin level prevents keratinocytes from migrating across the wound, thereby halting closure.
• Diagnostic Caution: If granulation tissue becomes hard, persistent, or cauliflower-like and does not respond to typical management, malignancy should be ruled out via biopsy.

Effective Management Strategies

• Identify Underlying Causes: Treat any infection, remove foreign material, address excess moisture, reduce mechanical irritation, and manage chronic edema.
• Topical Therapies: Mild corticosteroid ointments may be used for up to 10 days to suppress tissue overgrowth. Silver nitrate sticks or selective sharp debridement are alternatives when appropriate.
• Dressing Interventions: Use semi-occlusive or vapor-permeable dressings to control moisture and encourage flattening. Hypertonic saline dressings such as Mesalt® or Curasalt® help reduce edema and inhibit overgranulation.
• Surgical Options: In severe or refractory cases—particularly with burn wounds—sharp surgical removal or innovative debridement techniques may be warranted.
• Preparing for Skin Grafting: Hypergranulation must be controlled before skin grafting. Topical steroids, iodine preparations, or mechanical cleaning may be used to optimize the wound bed.

Hypergranulation is a manageable obstacle in wound care. With prompt identification and tailored treatment—combining topical, mechanical, and surgical approaches—clinicians can restore proper wound healing progression and promote epithelial coverage.

Keywords: hypergranulation, proud flesh, hypergranulation treatment, topical steroids, debridement

Read the full article on WoundsAfrica.com

WCC Certification Course Options: Get Wound-Care Credentialed

If you’re preparing for the Wound Care Certified (WCC®) exam, several structured pathways and course providers are available to boost your knowledge, readiness, and credentials.

Course Providers & Formats:

• NAWCO (via Prometric): Offers the formal WCC® credential through exam-based certification. Candidates must meet eligibility criteria (e.g., professional licensure + training or experience) to apply. Exam retakes are allowed up to four times. Credentials are valid for five years with NCCA accreditation through 2029.
• Wound Care Education Institute (WCEI): Delivers comprehensive wound-care courses—including WCC®, diabetic wound care, ostomy management—across onsite, live-online, and self-paced online formats. Four-day intensive courses are held nationwide throughout 2025‑2026.
• Wound Care Education Partners (WCEP): Provides a blended certification prep program (~25.5 CME/CEUs) with an online pre-course and 1‑day live workshop focused on core wound concepts and debridement, accredited by NAWCO.

Certification Pathways:

• Education-Based Path: Complete an approved skin and wound management training course. WCEI and WCEP courses meet NAWCO’s training criteria.
• Experience-Based Path: Clinical practice (e.g., ≥2 years full-time or equivalent part-time in wound care) may also qualify.
• Hybrid Options: Some candidates may combine prior wound-care credentials (e.g., CWCN, CWON) or documented experience instead of additional coursework.

Additional Details:

• Costs & Scheduling: Fees vary; online and live options are available year-round. Prometric testing centers schedule exams post-course completion.
• Recertification: WCC® credentials last five years and require continuing education for renewal. Many course providers also offer recertification workshops.
• Who’s Eligible? Professionals including RNs, PTs, OTs, physicians, podiatrists, and more. WCC® is recognized by Magnet and other clinical credentialing bodies.

Choosing between self-paced, live-online, or in-person workshops depends on your learning style, schedule flexibility, and preferred interaction level. All pathways are designed to ensure you’re fully prepared to sit for the WCC® exam and integrate evidence-based wound care into practice.

Keywords: WCC certification, wound care training, NAWCO, WCEI, wound care education

Read more on WoundCareProf.com

Pressure Injury: Integrating Scientific Evidence into Clinical Practice

A July 2025 editorial in *Advances in Skin & Wound Care* highlights the evolving body of evidence shaping pressure injury prevention and management. It emphasizes the importance of aligning care with the updated fourth edition of the International Pressure Injury Guideline, a living document that incorporates diverse evidence sources.

Key Highlights:

• Evidence Sources Vary: Clinicians can draw from expert opinion, patient preferences, case studies, randomized trials, systematic reviews, and clinical guidelines.
• Fourth Edition Guideline: The NPIAP–EPUAP–PPPIA International Pressure Injury Guideline is now in its fourth edition and updated continuously as new data emerges. It’s accessible for free online.
• Adaptation Is Essential: The editorial emphasizes that guideline statements must be customized to local settings—hospitals, long-term care, or community-based care—acknowledging resource variation and contextual differences.
• Living Guideline Model: This dynamic approach ensures rapid integration of emerging evidence into clinical recommendations, keeping practice current.

In essence, pressure injury prevention and treatment should be evidence-informed, context-specific, and adaptive to new scientific findings and evolving care environments.

Based on “Pressure Injury Scientific Evidence for Practice Change,” *Advances in Skin & Wound Care*, Volume 38, Issue 6—July 2025.

Keywords: pressure injury, clinical guidelines, NPIAP, international guideline, evidence-based practice

Read the full editorial on Advances in Skin & Wound Care

Phase III Gene Therapy Skin Grafts Accelerate Healing in Severe Epidermolysis Bullosa

Stanford Medicine researchers have reported success in a Phase III clinical trial using gene therapy–based skin grafts to treat recessive dystrophic epidermolysis bullosa (RDEB), a devastating genetic skin-blistering disease. The therapy, recently approved by the FDA, represents a major step forward in regenerative wound care for rare disorders.

Key Highlights:

• Improved Wound Healing: In a trial involving 11 RDEB patients, wounds treated with the engineered grafts healed significantly faster than untreated areas. Participants also experienced less pain and itching.
• FDA Approval: The treatment—marketed as ZEVASKYN™ (prademagene zamikeracel)—was approved by the FDA in April 2025, making it the first gene-corrected, cell-based therapy for RDEB.
• Patient Impact: Trial participants described the therapy as life-changing. One 20-year-old patient reported reduced pain and improved quality of life, allowing her to continue working during treatment.
• Durability & Safety: The grafts provided long-lasting healing with minimal side effects. No serious adverse events were reported, and follow-up showed continued skin integrity at the graft sites.

This milestone in wound care highlights the potential for autologous gene-modified grafts to transform treatment for rare and severe skin conditions, offering hope where conventional wound care often falls short.

Based on results published in June 2025 in The Lancet.

Keywords: gene therapy, skin grafts, epidermolysis bullosa, ZEVASKYN, RDEB

Read the full article on Medical Xpress

Custom-Made Footwear Boosts Adherence in High-Risk Diabetes Patients

An early report from the DIASSIST trial, published June 21, 2025 on DiabeticFootOnline, explores whether a multi-modal intervention can improve adherence to custom-made footwear in individuals at high risk for diabetic foot ulceration.

Key Highlights:

• Behavioural Strategy: The intervention paired structured education (using the Fragile Feet–Trivial Trauma model), motivational interviewing via phone, and custom-made indoor footwear.
• Study Participants: 53 people with healed ulcers and prescribed custom footwear were monitored for usage via embedded sensors; 57% had low adherence at baseline (<8 hours/day).
• Education Boost: Structured education led to a clinically meaningful increase in wear time (~+1 hr/day), though this did not reach statistical significance.
• Limited MI Impact: Motivational interviewing did not significantly affect adherence in this short-term evaluation.
• Footwear Matters: Custom indoor footwear produced a significant jump in wear time—+2.7 h/day for low adherence users and +2.0 h/day for high adherence users (p < 0.01).

Although the combined approach didn’t yield statistically significant overall changes at 3 months, the immediate and meaningful increase from indoor footwear highlights its potential as an effective, easy-to-implement measure in ulcer prevention protocols.

Based on Van Netten et al., “Short‑Term Efficacy of a Multi‑Modal Intervention Program to Improve Custom‑Made Footwear Use in People at High Risk of Diabetes‑Related Foot Ulceration,” J Clin Med, 2025;14(11):3635.

Keywords: custom footwear, footwear adherence, diabetic foot ulcer, education intervention, indoor footwear

Read the full article on DiabeticFootOnline

Must Wound Clinics & Mobile Practitioners Report Pressure Injuries at Home as Serious Reportable Events?

In a recent post, Dr. Caroline Fife alerts healthcare providers to key updates from the National Quality Forum’s (NQF) new 2025 Serious Reportable Events (SREs) guidelines, which now impact outpatient and mobile wound care professionals. Community-based pressure injuries—including those that develop at home—may need to be reported under the revised definitions.

Key Highlights:

• Expanded SRE Scope: The 2025 update extends SRE reporting requirements to ambulatory settings, explicitly including hospital-based outpatient wound centers, office-based specialty clinics, and mobile wound care providers.
• Pressure Injuries Included: Stage 3, Stage 4, and deep tissue injuries that are both “acquired after admission” and deemed “likely avoidable” now qualify as reportable events—covering injuries that emerge in the home.
• Key Definitions Challenged: The terms “likely avoidable,” “patient harm” (including emotional or functional impairment), and “after admission” create complexities in outpatient contexts—especially when patients were not “admitted” in the traditional sense.
• Reporting Ambiguity: Dr. Fife notes uncertainty around responsibility: Will mobile practitioners and clinics be held accountable? Must cases be reported to state health departments through HOPD or hospital systems?
• Stage Shift Concern: Since 2016, classification updates by NPIAP mean even superficial lesions may be labeled Stage 3, raising concerns that minor wounds could now trigger mandatory SRE reporting.

This advisory calls for practitioners to review the proposed SRE language and submit comments by the July 1, 2025 deadline—especially regarding definitional clarity in outpatient settings.

Source: Caroline Fife, M.D. – “Must Wound Clinics & Mobile Practitioners Report Pressure Injuries / Ulcers Occurring in the Home as SREs?” June 20, 2025.

Keywords: pressure injuries, serious reportable events, ambulatory settings, mobile wound care, regulatory policy

Read the full article on CarolineFifeMD.com

Understanding the Link Between Sitting and Pressure Ulcer Risk: New Seating Guidelines

The Society of Tissue Viability has launched the third edition of its Seating Guidelines, spotlighting the often-overlooked connection between prolonged sitting and the development of pressure ulcers. These evidence-based recommendations are designed to help clinicians, caregivers, and patients reduce risk and improve outcomes—especially for adults with limited mobility.

Key Highlights:

• Guideline Launch: The new guidelines were introduced during a free webinar held on 25 June 2025, offering practical tools for health and social care professionals working in hospitals, home settings, and long-term care facilities.
• Scale of the Problem: Pressure ulcers affect over 700,000 people annually in the UK and cost the NHS an estimated £3.8 million per day. Many cases are preventable with proper seating assessment and interventions.
• Seating as a Risk Factor: Prolonged sitting places excessive pressure on high-risk areas such as the sacrum and ischial tuberosities. The updated guidelines explain how these pressure points contribute to tissue damage over time.
• Prevention Strategies: Recommendations include frequent repositioning, daily skin inspections, use of pressure-relieving cushions, good posture, appropriate chair fit, moisture management, and proper nutrition to support skin integrity.
• Collaborative Development: The guidelines were created with input from clinicians, carers, and individuals with lived experience, ensuring the content is accessible, relevant, and grounded in real-world care settings.

This update serves as a critical reminder that seating matters—and that evidence-based positioning and equipment can significantly reduce preventable pressure injuries, particularly in at-risk populations.

Source: Society of Tissue Viability – June 2025

Keywords: pressure ulcers, seating guidelines, pressure management, mobility, caregivers

Read more on the Society of Tissue Viability website

Type 2 Diabetes Management in Severely Obese Patients: Strategies & Surgical Options

A recent article on Diabetes In Control examines comprehensive treatment approaches for severely obese individuals with type 2 diabetes, highlighting lifestyle, pharmacotherapy, and advanced interventions like bariatric surgery.

Key Highlights:

• Stable Lifestyle Habits: Emphasizes consistent diet, exercise, and stress management to enhance glycemic control and reduce cardiovascular risk :contentReference[oaicite:1]{index=1}.
• Medications with Weight Benefits: GLP‑1 receptor agonists (e.g., semaglutide, tirzepatide) effectively improve glycemia and support weight loss; metformin remains the first-line therapy with favorable weight-neutral or weight-reducing effects :contentReference[oaicite:2]{index=2}.
• Bariatric & Metabolic Surgery: For those with BMI ≥ 35 kg/m², procedures like sleeve gastrectomy, gastric bypass, and ileal interposition show substantial reductions in HbA1c—often leading to diabetes remission—and increased life expectancy :contentReference[oaicite:3]{index=3}.
• Integrated Care Approach: The most effective management combines multidisciplinary support—nutrition, physical therapy, psychological care—with pharmacologic agents and, when needed, surgical interventions.

This article reinforces that managing type 2 diabetes in obese patients demands a personalized and progressive strategy—starting with lifestyle optimization, advancing to weight-friendly medications, and considering metabolic surgery for eligible individuals when conservative methods do not achieve control.

Source: Diabetes In Control (June 2025)

Keywords: type 2 diabetes, obesity, GLP‑1 agonists, bariatric surgery, weight management

Read the full article on Diabetes In Control

The Financial Burden of Chronic Wounds in Primary Care: A Real-World Cost Analysis

A 2025 study published in the *International Wound Journal* offers one of the most comprehensive real-world analyses of the cost and prevalence of chronic wounds in primary care settings. Drawing on extensive electronic medical records from Italy, the study sheds light on the significant economic and clinical impact of treating chronic wounds such as diabetic foot ulcers (DFUs), pressure injuries (PIs), venous leg ulcers (VLUs), and arterial ulcers (AUs).

Key Highlights:

• Study Scope: Over 7,400 patients with chronic wounds were identified across 1.6 million+ medical records. Wound types included DFUs (27.6%), VLUs (25.4%), PIs (23.7%), AUs (7.8%), and others (15.4%).
• Economic Impact: The average annual cost per patient ranged from €3,468 (VLUs) to €5,748 (DFUs). Medication and home care were the main cost drivers, with wound dressings accounting for over 50% of costs.
• Comorbidity Patterns: High rates of comorbidities were observed, including diabetes, hypertension, and cardiovascular disease—highlighting the complex medical management required for this population.
• Age and Gender Trends: Chronic wounds were more prevalent in older adults, with women representing a slight majority overall. However, DFUs were more common in men, especially over age 70.
• Policy Implications: The authors urge more proactive prevention, earlier intervention, and better resource allocation to address the growing burden of chronic wounds in aging populations.

This real-world study emphasizes the financial strain chronic wounds place on healthcare systems and reinforces the need for early, multidisciplinary intervention—particularly in primary care settings.

Based on findings published in the *International Wound Journal* (May 2025).

Keywords: chronic wounds, primary care, wound costs, diabetic foot ulcers, wound prevalence

Read the full article on the National Library of Medicine

Comparing Infrared Thermometry and Microwave Radiometry in Monitoring Charcot Foot

A new study published in *Chronic Wound Care Management and Research* evaluates the use of microwave radiometry (MWR) as an alternative to infrared thermometry in diagnosing and monitoring Charcot neuro-osteoarthropathy (CNO) in diabetic patients. The researchers explored how well MWR measurements of internal tissue temperatures agree with standard infrared thermometry, a common method used to detect early inflammatory changes in the diabetic foot.

Key Highlights:

• Study Design: The pilot study included 9 individuals with active CNO and 5 diabetic participants without CNO. Temperature was measured using infrared thermometry and MWR sensors of varying diameters (0.8 cm, 2 cm, and 5 cm) to assess different tissue depths.
• Measurement Agreement: MWR 0.8 showed strong agreement with infrared thermometry, with an average discrepancy of just 0.034°C (statistically insignificant). However, MWR 2 and MWR 5 showed larger differences (−0.323°C and −0.315°C, respectively), indicating less accuracy for deeper tissue assessment.
• Follow-Up Outcomes: Over a median of 67 weeks, 77.8% of participants with CNO had successful offloading with less than a 2°C skin temperature difference. Three participants experienced CNO reactivation weeks after offloading ended, highlighting the importance of precise monitoring during recovery.
• Clinical Implication: MWR may serve as a deeper tissue assessment tool, but infrared thermometry remains reliable—especially for surface temperature monitoring in early-stage CNO.

While microwave radiometry shows promise for internal tissue assessment, infrared thermometry remains a practical, cost-effective, and accurate method for tracking Charcot foot inflammation in most clinical settings.

Based on findings published in *Chronic Wound Care Management and Research* (2025).

Keywords:
Charcot foot,
infrared thermometry,
microwave radiometry,
diabetic foot,
offloading

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🔬 Spotlight: Tools for Temperature Monitoring in Diabetic Foot Management

Accurate temperature tracking is essential in the early detection and management of Charcot neuro-osteoarthropathy and other diabetic foot complications. Several modern tools now help clinicians and patients monitor inflammation with greater precision and consistency:

• Infrared Thermometers: Widely used handheld devices such as the TempTouch® or ThermoFlash® offer quick, non-contact surface readings that help identify at-risk feet before ulceration occurs.
• Microwave Radiometry Devices: Though still emerging, MWR systems allow for deeper tissue temperature assessment, potentially identifying inflammation not yet visible at the skin surface.
• Smart Insole Systems: Products like Podimetrics SmartMat® or Orpyx SI® continuously track plantar temperature patterns, alerting providers to early warning signs of ulcer formation or reactivation of Charcot foot.
• Mobile Integration: Some devices now sync with apps, allowing patients to transmit temperature trends remotely to care teams, supporting proactive intervention and improved adherence.

With technology evolving rapidly, integrating temperature-monitoring tools into diabetic foot protocols can significantly improve early detection, reduce hospitalization risk, and preserve limb function.

read full article

The Critical Need for Standardization in Wound Dressing Evaluation

A recent article from WoundSource highlights the urgent need to establish standardized approaches for evaluating and selecting wound dressings. Current practices suffer from inconsistency, making it difficult to ensure clinicians and patients receive the most appropriate, evidence-backed products. Standardization could streamline care, improve comparative effectiveness, and enhance patient outcomes. :contentReference[oaicite:1]{index=1}

Key Highlights:

• Variability in Dressings: Clinicians rely on a wide range of dressing types—films, foams, hydrocolloids, alginates, gelling fibres, NPWT, collagen, cadexomer iodine, honey-based options, and enzymatic debriders—with little consistency in evaluation criteria.
• Evaluation Framework Gaps: There’s a lack of consensus on essential metrics such as absorption rates, wear time, antimicrobial properties, patient comfort, cost-effectiveness, and ease of use.
• Need for Evidence-Based Tools: A call for validated lab and clinical testing protocols to compare dressing performance across key parameters like debridement support, moisture balance, and barrier function.
• Impact on Access and Outcomes: Without standardized evaluation, payers and providers face challenges in formulary decisions, potentially limiting patient access and inflating costs for suboptimal products.

This article emphasizes that establishing rigorous, universally accepted standards for dressing evaluation is essential—not only for clinical decision-making, but also for improving product quality, reimbursement clarity, and ultimately, patient care.

Read the full piece on the WoundSource website.

Keywords:
wound dressing evaluation,
standardization,
evidence-based dressings,
comparative effectiveness,
product access

After the Amputation: A Podiatrist’s Role in Postoperative Limb Preservation

Amputation is not the end of care—it’s the beginning of a new and critical phase. In this practice management piece, Dr. Andrew Schneider emphasizes the ongoing responsibilities podiatrists have after a patient undergoes a lower extremity amputation. Without proactive measures, patients are at high risk of stump breakdown, ulceration, and contralateral limb loss.

Key Highlights:

• Patient Education is Essential: Patients may feel depression, grief, or even shame following amputation—regardless of severity. Clinicians must guide them through the transition and reinforce that quality of life is still possible.
• Monitor the Stump: Even healed amputation sites are vulnerable. Regular evaluation for pressure points, breakdown, and poor prosthetic fit is necessary—especially in partial foot amputations like transmetatarsal or Chopart levels.
• Protect the Contralateral Limb: After one amputation, the risk to the remaining limb rises sharply. Podiatrists must deliver comprehensive diabetic foot care, monitor for PAD, and apply the Q7 modifier for at-risk billing when appropriate.
• Therapeutic Footwear is Not Optional: Post-amputation, custom toe fillers and accommodative insoles are critical to pressure redistribution. These are medical necessities—not just “free Medicare shoes.”
• Team-Based Follow-Up: Optimal care includes referrals to prosthetists, physical therapists, diabetic educators, nutritionists, and mental health professionals to ensure holistic support.

Ultimately, limb preservation doesn’t stop with the surgical wound closure. Podiatrists must remain engaged to prevent a cascade of complications—and to empower their patients toward better mobility and health.

Originally published in the Nov/Dec 2024 issue of Podiatry Management Magazine.

Keywords:
amputation,
stump care,
contralateral limb risk,
therapeutic footwear,
diabetic foot

Bridging the Gap: Communicating With Adolescents in WOC Nursing

A narrative review in the May–June 2025 issue of Journal of Wound Ostomy and Continence Nursing explores communication strategies for WOC nurses working with adolescent patients. The review emphasizes the importance of tailoring interactions to meet the unique developmental, cultural, and privacy needs of teens to improve trust, adherence, and long-term outcomes.

Key Highlights:

• Understanding Adolescent Development: Effective communication strategies must account for adolescents’ maturing cognitive skills, growing desire for independence, and heightened sensitivity to body image and social acceptance.
• Cultural Sensitivity & Privacy: Respecting cultural norms and protecting patient confidentiality—especially in areas like continence care or ostomy management—are essential to building trust and encouraging openness.
• Tech-Friendly Engagement: Adolescents are more responsive to mobile apps, social media, and tech-enabled platforms. Integrating digital tools can foster greater involvement, though privacy concerns must be managed carefully.
• Developmentally-Appropriate Communication: Using simplified language, visual aids, and allowing space for questions can help ensure adolescents understand treatment goals and self-care responsibilities.
• Fostering Autonomy: Age-appropriate communication empowers teens to manage their condition independently, supporting lifelong adherence and self-efficacy.

This review highlights the importance of communication that is culturally informed, privacy-conscious, and tailored to the adolescent developmental stage—ensuring better outcomes and more confident, engaged patients.

Read the full article in the Journal of Wound Ostomy and Continence Nursing.

Keywords:
WOCN communication,
adolescent health,
cultural competence,
patient engagement,
self‑management

Unna Boot Compression Enhances Limb Health in Chronic Venous Disease

A preliminary study (Jan 2025, *Journal of Wound Management*, Vol 26 No 1) assessed the effects of zinc oxide compression bandaging—using the traditional Unna boot—on patients with chronic venous disease. Objective measures included ultrasonography for edema and transepidermal water loss (TEWL) to evaluate skin barrier function. :contentReference[oaicite:1]{index=1}

Key Highlights:

• Leg Edema Reduction: High-frequency ultrasound revealed notable decreases in interstitial fluid and calf circumference, indicating effective edema control.
• Skin Barrier Restoration: TEWL rates decreased significantly after bandaging, suggesting improved skin integrity and reduced barrier disruption.
• Holistic Benefits: Combining mechanical compression with the emollient and anti-inflammatory effects of zinc oxide supports both tissue drainage and epidermal healing.
• Non-Invasive Monitoring: The use of ultrasonography and TEWL offers objective and repeatable ways to track treatment effectiveness beyond simple visual inspection.

This study reinforces the therapeutic value of Unna boots—not only in edema management but also in enhancing skin health—while highlighting the importance of measurable outcomes in chronic venous therapy.

Read the full article in Journal of Wound Management.

Keywords:
Unna boot,
zinc oxide compression,
ultrasonography,
TEWL,
chronic venous disease

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🔬 Spotlight: Modern Tools Supporting Zinc Oxide Compression Therapy

As evidence grows in support of zinc oxide–based compression therapy, especially for chronic venous disease, clinicians are turning to advanced tools that enhance both efficacy and assessment. Here are a few technologies and products driving better outcomes:

• Smart Compression Systems: Modern zinc oxide bandages, such as two-layer cohesive wraps, offer consistent sub-bandage pressure and easier application while retaining the therapeutic benefits of traditional Unna boots.
• TEWL Measurement Devices: Portable, non-invasive instruments allow clinicians to track trans-epidermal water loss, helping to assess skin barrier restoration in real time during wound and edema management.
• High-Frequency Ultrasound: Compact Doppler and ultrasound devices are increasingly used to objectively quantify edema and soft tissue fluid changes, improving treatment tracking for venous insufficiency.
• Barrier Recovery Adjuncts: Zinc oxide creams and dressings are now often paired with hydrating base layers or occlusive secondary dressings to reinforce epidermal healing and reduce irritation.

These tools reflect the merging of time-tested therapies with modern diagnostics—empowering clinicians to deliver more personalized and measurable venous wound care.

Core Services from a Multidisciplinary Diabetic Foot Team (ZAP Position Statement)

A position statement by the Zero All Preventable (ZAP) Amputation group of Foot in Diabetes UK (FDUK), published April 15, 2025 in The Diabetic Foot Journal, outlines the essential services that people with active diabetic foot problems should expect from a multidisciplinary diabetic foot team (MDFT).

Key Highlights:

• Team Composition: Core members should include podiatrists, diabetologists, vascular specialists, orthopaedic or podiatric surgeons, plastic surgeons, microbiologists or infectious disease physicians, specialist nurses, psychologists, orthotists, and plaster technicians—all coordinated by a designated MDFT lead.
• Timely Intervention: Debridement should be performed without delay—typically by a podiatrist—with immediate offloading and pressure redistribution initiated to reduce further tissue damage.
• Infection and Vascular Management: Patients should have rapid access to antibiotics and surgical debridement for infected wounds, alongside urgent vascular imaging and revascularization when ischemia is suspected.
• Referral and Prescribing Rights: Podiatrists should hold independent referral rights for imaging (e.g., X-ray, MRI) and, where supported, prescribing authority. Dedicated consultant podiatrists should oversee care coordination across both inpatient and outpatient settings.
• Mental Health Integration: Recognizing the emotional burden and high mortality rates associated with diabetic foot ulcers, mental health support must be embedded through liaison nurses or access to psychological services.

This position paper reinforces that fully staffed, responsive, and coordinated multidisciplinary teams—led by experienced podiatric clinicians—are critical in delivering timely care and reducing amputation risk in individuals with diabetes.

Read the full position statement on the Diabetic Foot Journal website.

Keywords:
ZAP Amputation,
multidisciplinary foot team,
debridement,
offloading,
psychological support

NPIAP 2025 Fall Seminar: Advancing Pressure Injury Prevention

The National Pressure Injury Advisory Panel (NPIAP) will host its 2025 Fall Seminar on November 13–14, 2025. This event provides a timely opportunity for healthcare professionals worldwide to deepen their knowledge and skills in pressure injury prevention, staging, and management.

Key Highlights:

• Interprofessional Focus: The seminar is open to clinicians, researchers, educators, and policymakers seeking to address challenges in pressure injury care through a multidisciplinary lens.
• Expert-Led Sessions: Topics include advanced staging techniques, care bundle implementation, case studies in complex settings, policy updates, and emerging evidence in PI prevention.
• Certification & Credits: Attendees earn continuing education credits (CEUs/CECH) and have access to Q&A panels, interactive workshops, and networking with international peers.
• Timing & Registration: The event kicks off with a welcome session on Nov 12, followed by two days of programming on Nov 13–14, 2025—registration details are available through the NPIAP website.

Learn more and register via the NPIAP Events page.

Keywords:
pressure injury prevention,
NPIAP,
staging workshop,
interprofessional care,
continuing education

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🔬 Spotlight: Tools Advancing Pressure Injury Prevention

As pressure injury care evolves, so does the technology that supports prevention and early intervention. At this year’s NPIAP Fall Seminar, attention turns to innovations making a measurable impact on patient outcomes and clinical workflows.

Featured Technologies:

• Smart Sensor Mats: Pressure-redistribution mats with integrated sensors provide real-time feedback on patient positioning, helping staff prevent prolonged pressure and improve repositioning adherence.
• Visual Staging Apps: Mobile tools that assist clinicians with wound staging through image capture and AI-guided classification, improving documentation accuracy.
• Silicone Border Dressings: Advanced foam and film dressings with soft silicone borders reduce shear and friction, particularly for patients at high risk in ICU or perioperative settings.
• Education Platforms: E-learning tools and staging simulation software help standardize knowledge among interprofessional teams, reinforcing evidence-based care protocols.

These solutions highlight how the intersection of technology, education, and evidence-based practice can reshape the future of pressure injury prevention and management.

Aiodine™ for Traumatic Wounds: Enhanced Healing and Infection Control

This case series, published March 26, 2025, in *Wounds International*, reports preliminary findings from four patients treated with **Aiodine™**, a novel topical iodine-based formulation. Conducted at Hainan Medical University’s Wound Department in China, the study highlighted accelerated wound healing and reduced infection in severe traumatic wounds.

Key Highlights:

• Broad-Spectrum Antimicrobial Activity: In vitro studies showed Aiodine™ achieves >5 log reduction against both Gram-positive and Gram-negative bacteria in just 30 seconds.
• Clinical Efficacy: All four patients—who had wounds such as diabetic foot ulcers, pressure injuries, and necrotic lesions—demonstrated significant healing improvements within two weeks, with dramatic reductions in infection rates.
• Excellent Tolerance: No adverse effects were reported. Patients experienced decreased wound discomfort and improved quality of life during treatment.
• Next Steps Required: Authors recommend larger randomized, double-blind, placebo-controlled trials to confirm Aiodine™’s safety and effectiveness in broader wound care applications.

Read the full case series and download the PDF: Wounds International – Aiodine™ Case Series.

Keywords:
Aiodine™,
iodine antimicrobial,
traumatic wound,
wound infection,
wound healing

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🔬 Spotlight: Aiodine™ – A New Era in Topical Antimicrobial Therapy

Aiodine™ is a next-generation topical antimicrobial solution designed to rapidly eliminate bacteria while supporting wound healing. Unlike traditional iodine formulations, Aiodine™ delivers broad-spectrum bactericidal action with improved tissue compatibility and no reported cytotoxicity in early clinical use.

What Sets It Apart?

• Delivers a >5-log bacterial reduction in 30 seconds
• Effective against antibiotic-resistant strains and biofilm-producing pathogens
• Non-cytotoxic and well-tolerated, even on fragile wound beds
• Supports granulation and epithelialization in complex or infected wounds

Backed by early clinical results in traumatic and chronic wounds, Aiodine™ may offer a valuable alternative in settings where both infection control and tissue preservation are critical.

The Hidden Human & Financial Toll of Pressure Ulcers

Pressure ulcers remain one of the most costly chronic wounds—financially and emotionally. In the US, hospital-acquired pressure injuries (HAPIs) cost over $26.8 billion annually, with Stage 3–4 ulcers disproportionately responsible. In England, the NHS spends approximately £3.8 million per day treating these injuries. Each non-healing ulcer can incur up to £374 per day in treatment costs.

Key Highlights:

• Health System Strain: Repairing full-thickness ulcers delays rehabilitation by preventing patients from participating in essential therapy. It also burdens staff and hospital budgets.
• Patient Suffering & Quality of Life: Patients describe ulcer pain as burning and sharp during dressing changes, along with unpleasant odour from anaerobic infection—which can lead to social isolation.
• Serious Complications: Pressure ulcer–related sepsis causes approximately 60,000 deaths per year in the US and 37,000 in the UK.

This article underscores that preventing pressure ulcers isn’t just a cost-saving measure—it directly improves patient wellbeing and survival. Implementing robust prevention, early detection, and treatment protocols should be a high priority for healthcare systems.

Read the full article on the Wounds International website.

Keywords:
pressure ulcers,
healthcare costs,
patient wellbeing,
sepsis,
prevention

Understanding and Managing Cavity Wounds

Fiona Downie from TVN‑TV offers practical insights into the assessment and treatment of cavity wounds—deep tissue defects that can extend beneath intact skin layers and complicate healing.

Key Highlights:

• Definition & Prevalence: Cavity wounds include sinuses, dehisced surgical sites, and deep ulcers. These wounds often go underreported due to inconsistent definitions in clinical audits.
• Assessment Best Practices: Effective evaluation includes probing for depth, noting undermining or tunneling, documenting exudate levels, identifying signs of infection, and photographing the wound for monitoring.
• Dressing Selection: Loose-packing with absorbent, conformable dressings like gelling fibres helps fill dead space and manage moisture. Dressings should be changed frequently enough to prevent maceration but not so often that they disrupt healing.
• Minimizing Trauma: Atraumatic dressings with silicone contact layers can reduce pain and skin stripping during dressing changes, which is critical for fragile or elderly patients.
• Case Application: One featured case used Exufiber® gelling fibre in a high-exudate cavity wound. The dressing absorbed fluid effectively, was easy to remove, and supported full closure in about 8 weeks.

This video-based resource reinforces the importance of careful wound assessment, strategic dressing use, and patient-specific planning for effective management of cavity wounds.

Watch the full video or access additional guidance on the TVN-TV website.

Keywords:
cavity wounds,
gelling fibre dressings,
Safetac,
debridement,
Exufiber

44th Annual Hawaii/Kauai Seminar on Foot & Ankle Care

The International Foot & Ankle Foundation (IFAF) is hosting its 44th Annual Hawaii/Kauai Seminar from October 20–24, 2025 at the Grand Hyatt Kauai Resort on Kauai’s stunning North Shore. This high-value event offers up to 25 continuing education credit hours (CECH) and merges expert-led lectures with hands-on workshops focused on foot and ankle conditions.

Key Highlights:

• Date & Venue: October 20–24, 2025 at Grand Hyatt Kauai Resort, Kauai, HI.
• Continuing Education Credits: Earn up to 25 CECH, as accredited by IFAF.
• Clinical Content: Topics include advanced foot and ankle pathology, surgical techniques, reconstructive care, and wound management strategies.
• Learning Format: Combines didactic lectures with small‑group practical sessions for technique refinement.
• Networking & Professional Growth: Ideal for podiatrists, surgeons, and allied health professionals seeking both professional enrichment and connection in a resort setting.

Learn more and register on the IFAF Scientific Seminars page.

Keywords:
Hawaii Kauai Seminar,
CECH,
foot & ankle care,
clinical workshops,
IFAF

First Clinical Evaluation of Tarumase® for Debridement in Venous Leg Ulcers

In this Podiatry Today video demonstration, clinicians present initial real-world data on **Tarumase®**, an enzymatic debriding agent, used for treating venous leg ulcers. The video follows its application in a clinical and outpatient context.

Key Highlights:

• Tarumase® Application: Applied topically to venous leg ulcer beds and covered with a semi‑permeable dressing, allowing enzymatic breakdown of non‑viable tissue while preserving healthy tissue.
• Clinical Efficacy: Initial cases demonstrate visible devitalized tissue removal within 24–48 hours, reducing manual debridement needs and enhancing wound bed readiness.
• Safety & Patient Comfort: Patients reported minimal pain and no systemic side effects. Application was well‑tolerated in outpatient settings, even in patients with comorbidities. :contentReference[oaicite:1]{index=1}
• Workflow Benefits: Clinicians highlighted that Tarumase® simplifies debridement protocols, enabling more efficient treatment cycles and better integration into multidisciplinary wound care routines.

This video provides a promising look at Tarumase® as an enzyme-based debridement tool that could complement or reduce dependence on sharp or mechanical methods in venous leg ulcer management.

Watch the full video on the HMP Global Learning Network.

Keywords:
Tarumase®,
venous leg ulcer,
enzymatic debridement,
outpatient care,
patient tolerance

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🔬 Spotlight: Tarumase® – Enzymatic Precision for Wound Debridement

Tarumase® is an advanced enzymatic debriding agent formulated to selectively break down necrotic tissue in chronic wounds—particularly venous leg ulcers—while preserving healthy granulating tissue. This topical therapy offers a gentle, effective alternative to mechanical or sharp debridement, making it suitable for both inpatient and outpatient wound care settings.

Early clinical evaluations highlight Tarumase’s ability to:

• Visibly reduce devitalized tissue within 24–48 hours
• Minimize pain and trauma during dressing changes
• Streamline wound bed preparation without requiring surgical expertise

Its targeted enzymatic action and user-friendly application have positioned Tarumase® as a valuable tool in modern wound healing protocols, especially for patients with comorbidities or limited surgical access.

Jingfang Granules Accelerate Diabetic Wound Healing via Multi‑Target Pathways

A recent manuscript in *Drug Design, Development and Therapy* reveals that Jingfang Granules (JFG), a traditional Chinese medicine blend of 11 herbs, significantly promotes healing of diabetic wounds in preclinical models. The study, using network pharmacology, molecular docking, and animal experiments, explores the mechanisms behind its efficacy.

Key Highlights:

• Multi-Mechanism Action: JFG alleviates oxidative stress, suppresses inflammation, promotes angiogenesis, and normalizes glucose and lipid metabolism—key processes impaired in diabetic wound healing.
• Strong Preclinical Results: In STZ-induced diabetic rats, JFG (1–2 g/kg) enhanced wound closure: day 8 closure improved from ~62% (untreated) to ~70–73%, and by day 14 reached ~95–96% vs 88% in controls.
• Phytochemical Targets Identified: Serum analysis found 56 active compounds. Network mapping highlighted six core protein targets—AKT1, EGFR, MAPK3, MAPK1, IL6, TNF—suggesting modulation of PI3K‑AKT and MAPK pathways.
• In Vitro Validation: JFG serum preparations protected endothelial (H₂O₂/glucose damage) and keratinocyte cultures; it reduced inflammatory cytokines and enhanced angiogenic behaviors.

By integrating computational and experimental data, this study provides compelling preclinical evidence that Jingfang Granules can effectively support diabetic wound healing through multi-dimensional molecular mechanisms.

Read the full study in Drug Design, Development and Therapy.

Keywords:
Jingfang Granules,
network pharmacology,
PI3K‑AKT pathway,
MAPK pathway,
diabetic wound healing

Multistep Heel Reconstruction After Marjolin Ulcer Resection

A case series in *Wounds* (June 17, 2025) details four patients undergoing multistep reconstruction of the heel following resection of Marjolin ulcers—aggressive skin cancers arising in chronic wounds. Researchers used a biosynthetic extracellular matrix (BECM) combined with negative pressure wound therapy (NPWT) to achieve durable closure without traditional flap surgery.

Key Highlights:

• Patient Population: Four adults with posttraumatic chronic leg ulcers, including a 58-year-old male with diabetes, venous insufficiency, obesity, smoking, and a Marjolin ulcer on the heel. :contentReference[oaicite:1]{index=1}
• Multistep Protocol:
  1. Wide surgical excision of tumor + placement of BECM with 28 days of NPWT
  2. Application of split-thickness skin graft and 7 additional days of NPWT

  :contentReference[oaicite:2]{index=2}

• Outcomes: All four patients achieved stable wound closure by day 38, with good scar quality and high patient satisfaction. No tumor recurrence or complications occurred during 12 months of follow‑up. :contentReference[oaicite:3]{index=3}
• Clinical Advantages: The BECM + NPWT approach avoids flap surgery, reduces donor-site issues, offers shorter operative time and hospital stay, and delivers a robust tissue fill that restores heel contour and function. :contentReference[oaicite:4]{index=4}
• First in the Literature: This is the first reported use of combined biosynthetic matrix and NPWT for heel reconstruction following Marjolin ulcer resection. :contentReference[oaicite:5]{index=5}

A multistep reconstruction strategy using biosynthetic scaffold plus NPWT offers a practical, less invasive solution for complex heel defects—achieving functional and aesthetic outcomes without flaps or extensive surgery.

Read the full case series in Wounds (HMP Global Learning Network).

Keywords:
Marjolin ulcer,
biosynthetic extracellular matrix,
NPWT,
heel reconstruction,
case series

Multistep Heel Reconstruction After Marjolin Ulcer Resection

A case series in *Wounds* (June 17, 2025) details four patients undergoing multistep reconstruction of the heel following resection of Marjolin ulcers—aggressive skin cancers arising in chronic wounds. Researchers used a biosynthetic extracellular matrix (BECM) combined with negative pressure wound therapy (NPWT) to achieve durable closure without traditional flap surgery.

Key Highlights:

• Patient Population: Four adults with posttraumatic chronic leg ulcers, including a 58-year-old male with diabetes, venous insufficiency, obesity, smoking, and a Marjolin ulcer on the heel. :contentReference[oaicite:1]{index=1}
• Multistep Protocol:
  1. Wide surgical excision of tumor + placement of BECM with 28 days of NPWT
  2. Application of split-thickness skin graft and 7 additional days of NPWT

  :contentReference[oaicite:2]{index=2}

• Outcomes: All four patients achieved stable wound closure by day 38, with good scar quality and high patient satisfaction. No tumor recurrence or complications occurred during 12 months of follow‑up. :contentReference[oaicite:3]{index=3}
• Clinical Advantages: The BECM + NPWT approach avoids flap surgery, reduces donor-site issues, offers shorter operative time and hospital stay, and delivers a robust tissue fill that restores heel contour and function. :contentReference[oaicite:4]{index=4}
• First in the Literature: This is the first reported use of combined biosynthetic matrix and NPWT for heel reconstruction following Marjolin ulcer resection. :contentReference[oaicite:5]{index=5}

A multistep reconstruction strategy using biosynthetic scaffold plus NPWT offers a practical, less invasive solution for complex heel defects—achieving functional and aesthetic outcomes without flaps or extensive surgery.

Read the full case series in Wounds (HMP Global Learning Network).

Keywords:
Marjolin ulcer,
biosynthetic extracellular matrix,
NPWT,
heel reconstruction,
case series

Managing Wound Risks in Patients on TKIs

Tyrosine kinase inhibitors (TKIs), widely used in cancer therapy, can impair wound healing by inhibiting pathways critical for tissue repair—such as VEGFR, EGFR, FGFR, and PDGFR. A recent review highlights the need for tailored perioperative planning and interdisciplinary collaboration to mitigate these risks.

Key Highlights:

• Mechanism of Impaired Healing: By blocking angiogenesis, fibroblast activity, and keratinocyte function, TKIs increase risk for delayed healing, dehiscence, ulceration, and fistula development. Common agents include sunitinib, cabozantinib, lenvatinib, and sorafenib. :contentReference[oaicite:1]{index=1}
• Clinical Evidence: Of the 24 TKIs reviewed, many are cited in phase II trials and case reports showing significant wound complications—e.g., cabozantinib associated with grade 3–5 healing problems in ~24% of patients. :contentReference[oaicite:2]{index=2}
• Perioperative Strategies: Since TKIs’ half-lives vary (e.g., sunitinib ~51 hours), therapy cessation 1–2 weeks before surgery is advised, with resumption only after confirmed healing. :contentReference[oaicite:3]{index=3}
• Interdisciplinary Coordination: Optimal care relies on collaboration among dermatologists, surgeons, and oncologists—especially for patients undergoing skin surgery like Mohs, grafting, or chronic wound management. :contentReference[oaicite:4]{index=4}

This review underscores the importance of awareness among dermatology and surgical teams when treating patients on TKIs, ensuring appropriate timing of interventions to support wound integrity.

Read the full article on the Dermatology Times website.

Keywords:
TKI wound healing,
tyrosine kinase inhibitors,
perioperative management,
angiogenesis,
dermatology-oncology collaboration

Hyperbaric Oxygen Accelerates Healing Assessed by Thermal Imaging & Planimetry

A 2019 clinical study from Poland evaluated 142 patients with chronic leg ulcers—caused by venous insufficiency or diabetic foot syndrome—undergoing 30 sessions of hyperbaric oxygen therapy (HBOT). Healing progress was monitored using both computerized planimetry and thermal imaging. :contentReference[oaicite:1]{index=1}

Key Highlights:

• Digital Measurements: Computerized planimetry showed significant reductions in wound surface area and perimeter following HBOT across both ulcer types. :contentReference[oaicite:2]{index=2}
• Thermal Imaging Insights: Thermographic scans detected inflammation-related temperature differences, which narrowed significantly after treatment (ΔT between ulcer center and periwound dropped from 0.9 °C to 0.3 °C). :contentReference[oaicite:3]{index=3}
• Correlated Monitoring: Thermal and planimetric data were strongly correlated, though they measured different aspects—metabolic activity versus structural size. :contentReference[oaicite:4]{index=4}
• Clinical Value: Combining thermal imaging and planimetry offers a non-invasive, objective way to track both physical and physiological healing responses to HBOT.

These findings support HBOT’s effectiveness in chronic wound care and highlight the potential of combined imaging methods to enhance diagnostic accuracy and treatment monitoring.

Read the full study on PubMed Central.

Keywords:
hyperbaric oxygen therapy,
thermal imaging,
planimetry,
chronic leg ulcer,
venous insufficiency

Global Preventive Foot Care Delivers Promising Reductions in Amputations

Featured in *Limb Preservation Journal* (Vol 6 No 1, Wounds Canada), this initiative outlines a comprehensive training program—Train the Foot Healthcare Professional (TtFHCP)—implemented across six WHO regions from 2023 to 2025. The goal: empower local providers to effectively screen, assess, and manage diabetic foot complications with minimal resource dependence. Download the full PDF.

Key Highlights:

• Program Reach: Delivered in six WHO regions, TtFHCP enhances the skills of clinicians and allied professionals in foot screening, offloading, callus care, and ulcer recognition. :contentReference[oaicite:1]{index=1}
• Improved Outcomes: Early results indicate reductions in ulcer incidence and need for amputation in trained communities, reinforcing the value of proactive foot care. :contentReference[oaicite:2]{index=2}
• Resource-Level Strategies: Emphasis on practical interventions—callus removal, offloading, patient education—designed for implementation in settings with limited access to specialized wound services. :contentReference[oaicite:3]{index=3}
• Introducing STIMULAN®: In locations where foot infections occurred despite preventive care, localized antibiotic therapy using **Stimulan®** calcium sulfate beads was trialed. This infection-focused strategy aims to reduce progression to diabetic foot osteomyelitis, supported by emerging clinical and in vitro evidence. :contentReference[oaicite:4]{index=4}

This program exemplifies how scalable, education-driven preventive foot care—augmented with available adjunct therapies like local antibiotic-loaded beads—can significantly reduce diabetic foot complications on a global scale.

Read the full report and download the PDF from Wounds Canada via the link above.

Keywords:
preventive foot care,
diabetic foot complications,
amputation prevention,
Stimulan® beads,
local antibiotic therapy

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🔬 Product Spotlight: Stimulan® in Global Wound Care

As part of adjunctive care in settings with recurrent or hard-to-control infections, **Stimulan®** calcium sulfate beads are gaining traction. These absorbable beads can be loaded with antibiotics like vancomycin or gentamicin and placed directly into the wound site—providing high local antibiotic concentrations while minimizing systemic exposure. In early-stage wound infections identified through the TtFHCP model, Stimulan® offers a promising tool to halt bacterial spread and support tissue preservation, even in low-resource environments.

Its role in limb salvage continues to grow as more programs integrate localized antimicrobial delivery into diabetic foot protocols. Clinicians using Stimulan® report reduced recurrence rates and improved wound bed preparation prior to definitive closure or offloading.

Treating Blistered and Callused Diabetic Feet in Barbados: A Limb Preservation Case

A clinical case report from the 2025 issue of *Limb Preservation Journal* (Vol 6 No 1, Wounds Canada) presents the successful management of a diabetic foot featuring both callus and blistering. The protocol integrates callus debridement, patient education, offloading, and innovative local antibiotic therapy to prevent ulceration and preserve limb function.

Key Highlights:

• Clinical Presentation: A diabetic patient in Barbados developed a painful blister within a callused area of the foot—an early warning sign of potential ulceration and infection.
• Intervention Strategy:
  • Expert debridement of both callus and blister to remove vulnerable tissue and reduce bacterial burden.
  • Implementation of offloading footwear and reinforced patient education on daily foot inspection.
  • Critical use of antibiotic-loaded **Stimulan®** calcium sulfate beads placed into debrided tissue to target local contamination—an approach backed by clinical evidence in diabetic foot osteomyelitis :contentReference[oaicite:1]{index=1}.
• Outcome: The blister healed fully without progression to ulceration or infection. Limb integrity and function were preserved.
• Community Context: Demonstrates that effective limb preservation is achievable in resource-limited outpatient clinics through proactive, multidisciplinary care and use of localized antibiotic strategies.

This case underscores the value of early debridement, patient education, offloading, and strategic use of localized antibiotic therapy (such as Stimulan® beads) in preventing diabetic foot ulcers and possible amputations.

Read the full case report in *Limb Preservation Journal* via Wounds Canada (PDF available): Download the PDF.

Keywords:
diabetic foot callus,
blister,
limb preservation,
debridement,
Stimulan® beads

IPAWS & Tissue Repair Summit 2025: Two-Day Deep Dive into Wound Care Innovation

The International Post-Acute Wound Care Society (IPAWS) & Tissue Repair Summit will take place November 13–14, 2025 (welcome event on November 12), at The Ritz-Carlton, New Orleans. The two-day summit features three concurrent educational tracks and is designed to give attendees a flexible, interdisciplinary learning experience.

Key Highlights:

• Three Tailored Learning Tracks:
  • Track 1 – Tissue Repair Evidence: Focus on cutting-edge research, cellular and acellular therapies, and recent clinical trials.
  • Track 2 – Post‑Acute & Mobile Care: Practical strategies for mobile wound care models and post-acute management.
  • Track 3 – Plenary Sessions: Cross-disciplinary content including payer policy updates, real-world evidence publication, intelligent therapy selection, and collaboration strategies.
• Poster Reception & Networking: The popular “Wine & Wounds” reception on Nov 13 invites attendees to engage with poster presenters and peers in a relaxed environment.
• Collaboration & Flexibility: Attendees can move freely between sessions across tracks to tailor their experience to their professional needs.
• CME & Journal Access: Earn up to 12 CME credits and receive complimentary access to the newly launched *International Journal of Tissue Repair* (IJTR).
• Venue & Registration: Held at The Ritz-Carlton New Orleans (group rate $299/night until Aug 22). The first 50 registrants attend free (excluding travel/lodging); early bird pricing follows.

Learn more and register via the IPAWS Summit website.

Keywords:
IPAWS 2025,
tissue repair,
post‑acute care,
mobile wound care,
continuing education

Time in Range Predicts Healing Time in Diabetic Foot Ulcers

A pilot prospective study conducted at Vall d’Hebron Hospital Campus (Barcelona) evaluated whether continuous glucose monitoring (CGM) metrics—specifically Time in Range (TIR), Time Above Range (TAR), and Glucose Management Indicator (GMI)—correlate with healing duration in outpatients with uncomplicated diabetic foot ulcers (DFUs, University of Texas Grades I–II Stage A–C).

Key Highlights:

• CGM Metrics Matter: Higher TIR was strongly associated with faster ulcer closure (p = 0.005), while prolonged TAR and elevated GMI were linked to slower healing (p < 0.05).
• Practical Outpatient Use: CGM devices were worn until wound closure, offering real-time glycemic data in a typical outpatient setting, enhancing its clinical relevance.
• Impact on Wound Care: These findings suggest that optimizing TIR can actively influence DFU healing timelines, moving beyond HbA1c as the sole indicator of glycemic control.

This study strengthens the growing evidence that CGM-derived TIR is a valuable biomarker for predicting and potentially improving healing outcomes in diabetic foot ulcers.

Read the full article in Wound Repair & Regeneration.

Keywords:
Time in Range,
continuous glucose monitoring,
diabetic foot ulcer,
wound healing,
glycaemic control

Redefining Wound Healing: Point‑of‑Care Near‑Infrared Spectroscopy

A feasibility study by Andersen et al., published in *Advances in Skin & Wound Care* (May 2024), evaluated a portable, non-contact Near‑Infrared (NIR) imaging device (Snapshot NIR) to objectively assess wound healing progress. :contentReference[oaicite:1]{index=1}

Key Highlights:

• Objective Healing Metric: The device measures tissue oxygen saturation (StO₂) up to 2–3 mm beneath the wound surface, offering physiological data beyond visual inspection. :contentReference[oaicite:2]{index=2}
• Healing Delays Uncovered: In a cohort of 15 patients with lower extremity wounds, complete StO₂ normalization occurred an average of 13.5 days (median 12, range 0–35) after visual re-epithelialization. :contentReference[oaicite:3]{index=3}
• Guiding Clinical Decisions: By identifying continued physiological healing beneath intact epithelium, Clinicians can better determine safe timing for removing protective dressings and advising gradual return to full activity. :contentReference[oaicite:4]{index=4}
• Feasibility for Practice: The point‑of‑care, non-contact NIR tool enables repeatable, objective monitoring and may reduce wound recurrence risk by informing return-to-activity timelines. :contentReference[oaicite:5]{index=5}

This NIRS-based imaging approach redefines “healed” wounds by adding depth‑resolved physiological insight, helping clinicians tailor dressing changes and promote safer patient recovery.

Read the full study in Advances in Skin & Wound Care.

Keywords:
near-infrared spectroscopy,
Snapshot NIR,
tissue oxygenation,
wound assessment,
wound recurrence

SmartMat Delivers Preventative TelePodiatry Care for Veterans

The VA’s Remote Temperature Monitoring (RTM) program, using the Podimetrics SmartMat, enables daily foot temperature readings for veterans with diabetes, automatically transmitted to their VA care teams. This early detection tool helps identify hotspots—often up to five weeks before a diabetic foot ulcer appears—and allows proactive intervention. :contentReference[oaicite:1]{index=1}

Key Highlights:

• Early Warning Signs: A temperature increase of ≥2.2 °C at the same location over two days triggers alerts to veterans and their VA podiatry teams, prompting closer inspection. :contentReference[oaicite:2]{index=2}
• High Adoption & Reach: Over 8,100 veterans across 158 VA sites are enrolled; participation surged from ~20 to 247 at one center during COVID‑19. :contentReference[oaicite:3]{index=3}
• Outcome Improvements: Studies show using the SmartMat reduces hospital admissions, foot ulcer development, and amputations—evidenced by a 91% relative risk reduction in one cohort. :contentReference[oaicite:4]{index=4}
• Veteran Impact: Users report reduced clinic visits and greater confidence in managing their diabetes, allowing more time with family. :contentReference[oaicite:5]{index=5}
• Expanding Innovation: The VA is piloting other technologies—like smart insoles and socks—for continuous foot surveillance. :contentReference[oaicite:6]{index=6}

By detecting ulcer precursors up to five weeks earlier than traditional methods, the SmartMat program offers a scalable, preventive approach to reducing diabetic foot complications and improving quality of life among veterans.

Read more on the VA News website.

Keywords:
SmartMat,
remote temperature monitoring,
diabetic foot ulcer,
telepodiatry,
early intervention

Classifying Obesity as a Chronic Disease: Insights from Dr. W. Timothy Garvey

In a recent HCPLive interview, Dr. Garvey discusses the Lancet Commission’s updated obesity framework, highlighting the shift toward defining obesity as a chronic, adiposity-based disease. This approach recognizes both “preclinical” and “clinical” stages of obesity and acknowledges its wide-ranging health complications.

Key Highlights:

• Adiposity-Based Chronic Disease (ABCD): Dr. Garvey emphasizes replacing “BMI-defined obesity” with the term “adiposity-based chronic disease,” reflecting true pathophysiology and treatment focus.
• Preclinical vs Clinical Obesity: “Preclinical obesity” refers to excess body fat without complications, while “clinical obesity” includes adiposity linked to metabolic or physiologic issues.
• Chronic Disease Status: Obesity is a lifelong condition with measurable morbidity and mortality risks, comparable to diabetes or hypertension.
• Guideline Adoption: Major organizations like ACE and the European Association for the Study of Obesity now support this classification, aligning treatment standards globally.

Dr. Garvey’s insights call for recognition of obesity as a biologically driven chronic disease that extends beyond simple weight metrics, urging clinicians to apply comprehensive, pathology-centered strategies in assessment and management.

Watch the full interview on the HCPLive website.

Keywords:
adiposity-based chronic disease,
obesity classification,
preclinical obesity,
chronic disease,
Dr. Garvey

Pemphigus Vulgaris: Clinical Aspects and Evidence‑Based Management

This June 2025 review in *Advances in Skin & Wound Care* by Geng & Sibbald examines pemphigus vulgaris (PV)—a rare, potentially life-threatening autoimmune blistering disorder—covering its presentation, diagnostic methods, and therapeutic strategies. :contentReference[oaicite:1]{index=1}

Key Highlights:

• Clinical Presentation: PV typically begins with painful oral mucosal erosions, followed by fragile flaccid skin blisters that rupture to form erosions. Disease onset is most common between ages 40–60. :contentReference[oaicite:2]{index=2}
• Diagnostic Approach: Confirmatory testing includes direct immunofluorescence demonstrating IgG and C3 deposits, and serologic detection of anti–desmoglein 1/3 antibodies. :contentReference[oaicite:3]{index=3}
• Risk & Prognosis: Untreated mortality rates range from 5–30%. Historically fatal, outcomes have dramatically improved with current immunosuppressive regimens. :contentReference[oaicite:4]{index=4}
• Therapeutic Strategies: Systemic corticosteroids remain foundational, often combined with steroid-sparing agents. Biologics like rituximab are becoming frontline options. :contentReference[oaicite:5]{index=5}
• Wound Care Considerations: Management involves careful use of non-adherent dressings, infection prevention, and interdisciplinary coordination akin to burn strategies. :contentReference[oaicite:6]{index=6}

This review offers wound care clinicians a concise yet comprehensive guide to identifying, diagnosing, and managing PV with up-to-date, evidence-based recommendations.

Read the full article in Adv Skin Wound Care.

Keywords:
pemphigus vulgaris,
autoimmune blistering,
immunofluorescence,
rituximab,
wound care dressings

Best Practices in Debridement: Techniques, Tools & Teamwork

Vascular surgeon Dr. John Lantis and wound care specialist Dot Weir walk through a hands‑on demonstration from SAWC Spring 2025, covering sharp debridement best practices across inpatient, outpatient, and bedside settings.

Highlights:

• Fundamental Preparation: Emphasis on cleansing both wound and peri‑wound areas (4–6 cm beyond edges) with low‑cytotoxic antiseptics—saline alone isn’t sufficient.
• Sterile Setup & Patient Comfort: Use of barrier drapes (e.g., opened instrument packaging), proper positioning, informed consent, and pain control (topical or infiltrative lidocaine).
• Instrument Technique: Sharp tools like #10 and #15 scalpel blades, curettes, scissors, and forceps are used at a 45° bevel that promotes healthy punctate bleeding without damaging tissue.
• Hemostasis & Dressing: Techniques to manage bleeding—pressure, hemostatic agents—and post-debridement cleanse to prepare for dressing application.
• Peri‑wound Awareness: Attention to skin beyond the wound itself, ensuring clean margins to prevent contamination and promote optimal healing.

This demonstration provides clear, actionable guidance to enhance debridement safety, efficacy, and patient comfort across care settings.

Watch the full video above or on the HMP Global Learning Network.

Keywords: debridement, sharp debridement, peri‑wound care, aseptic technique, pain management

Bioengineered Autologous Skin Doubles Healing Speed in Preclinical Burn Model

Researchers from Tel Aviv University and Sheba Medical Center have developed a novel bioengineered skin graft using a patient’s own cells grown on a nanofiber scaffold. In preclinical full-thickness burn models, this graft enabled wound closure in just four days—half the time compared with standard treatments.

Key Highlights:

• Autologous Construction: Skin cells (fibroblasts and keratinocytes) were grown on a biodegradable PCL nanofiber scaffold enhanced with a bioactive peptide to support natural cell organization and adhesion.
• Structural Resilience: Unlike cultured epidermal autografts (CEAs), which can shrink over 50% and tear easily, this graft is flexible, durable, and easy to handle.
• Rapid Burn Healing: In animal models, 50% wound closure occurred within 4 days—compared to 8 days using standard care—while early regrowth of skin appendages like hair follicles was observed.
• Clinical Translation Potential: Made entirely from a patient’s own cells, using FDA-approved materials, and produced at scale via electrospinning, positioning it well for future human trials.
• Next Steps: The team plans additional preclinical testing, regulatory pathways, and eventual clinical trials to bring this technology closer to bedside application.

Read the full article on the MedicalXpress website.

Keywords:
bioengineered skin,
autologous graft,
nanofiber scaffold,
burn healing,
preclinical study

Time in Range as a Predictor of Diabetic Foot Ulcer Healing

A prospective study reported on June 16, 2025, in DiabeticFootOnline.com highlights the use of continuous glucose monitoring (CGM)–derived Time in Range (TIR) as a valuable predictor of healing time in patients with non-complicated diabetic foot ulcers (DFUs, grade I–II, stage A–C).

Key Highlights:

• Strong Correlation with Healing: Higher TIR (blood glucose within target range) was significantly associated with faster DFU healing (p = 0.005), while elevated Time Above Range and Glucose Management Indicator correlated with slower wound closure (p < 0.05). :contentReference[oaicite:1]{index=1}
• Real-world Application: Patients wore CGM devices from baseline until complete wound closure under standard outpatient care, demonstrating TIR’s practical value in routine clinical settings. :contentReference[oaicite:2]{index=2}
• Glycemic Control Matters: Findings support the concept that maintaining optimal glycemic stability via CGM can directly influence wound healing outcomes in DFUs. :contentReference[oaicite:3]{index=3}

These results reinforce growing evidence—such as the PubMed-listed study in *Wound Repair and Regeneration* (May–June 2025)—that TIR is a reliable biomarker for predicting DFU healing time in type 2 diabetes. :contentReference[oaicite:4]{index=4}

Read the full article on DiabeticFootOnline.com.

Keywords:
Time in Range,
continuous glucose monitoring,
diabetic foot ulcer,
wound healing,
glycemic control

Healthcare‑Acquired Wound Infections & Antimicrobial Resistance: Embracing a Multidisciplinary Team Approach

Presented on June 19, 2025, this free, on‑demand webinar by WoundSource addresses the growing risks of hospital‑acquired wound infections and the escalating problem of antimicrobial resistance (AMR). Featuring insights for clinicians on integrating multidisciplinary strategies for prevention, management, and stewardship.

Key Highlights:

• Rising Infection Risks: Covers the prevalence and serious complications associated with healthcare‑acquired wound infections, including surgical site infections, device‑related wounds, and pressure injuries. :contentReference[oaicite:1]{index=1}
• Antimicrobial Resistance Challenge: Discusses how multidrug-resistant organisms complicate treatment, leading to increased morbidity, mortality, and healthcare costs. :contentReference[oaicite:2]{index=2}
• Multidisciplinary Protocols: Emphasizes collaborative best practices involving infection control experts, microbiologists, pharmacists, nursing staff, and wound specialists to optimize prevention and management.
• Stewardship Strategies: Promotes antimicrobial stewardship programs, including robust surveillance, appropriate antibiotic selection, targeted therapy, and review of antibiotic duration to minimize resistance pressure.
• Clinical Practice Adaptations: Highlights the use of evidence‑based dressings, modality selection, debridement protocols, and early identification to reduce colonization and infection rates.

Watch the full webinar on the WoundSource website.

Keywords:
healthcare-acquired infections,
antimicrobial resistance,
multidisciplinary team,
antimicrobial stewardship,
wound infection prevention

Expediting Acute Wound Healing via Multimodal Therapy: A Case Series

A prospective case series published in *Wound Management & Prevention* (Dec 2024) by Gallagher et al. reports outcomes from 124 patients with complex acute surgical or traumatic wounds treated using a combination-therapy approach at Christiana Care’s Acute Surgical Wound Service.

Key Highlights:

• Patient & Wound Spectrum: 124 adult patients with diverse acute wounds (up to 1120 cm³) treated from admission through healing.
• Timely Specialist Involvement: Median time to wound specialist consult was just 2 days post-injury. :contentReference[oaicite:1]{index=1}
• Integrated Treatment Protocol: All patients received hypochlorous acid–based cleanser paired with negative pressure wound therapy, collagen, silver, manuka honey, and/or advanced foam dressings. :contentReference[oaicite:2]{index=2}
• Strong Healing Response: The median healing time was 19 days across 366 wounds, indicating rapid recovery. :contentReference[oaicite:3]{index=3}
• Barriers Identified: Smoking, immunocompromise, and limited access to supplies were linked to delayed healing. :contentReference[oaicite:4]{index=4}

This mixed-modality strategy—with prompt wound specialist intervention and targeted therapeutics—substantially decreased healing time, reduced healthcare visits, and improved resource use, suggesting a scalable model for acute wound services.

Read the full case series in the archived issue of Wound Management & Prevention.

Keywords:
multimodal wound therapy,
hypochlorous acid cleanser,
negative pressure wound therapy,
complex acute wounds,
Christiana Care

Thermal Imaging and Planimetry to Monitor Chronic Wound Healing Progress

A clinical study evaluated the use of thermal imaging combined with planimetry (area measurement) to assess healing in venous leg ulcers undergoing treatment, including compression and topical therapy.

Key Highlights:

• Thermal Patterns Reflect Healing: Wounds showed characteristic temperature changes: inflamed, non-healing wounds displayed elevated thermal readings, whereas temperature profiles normalized as healing progressed.
• Planimetry Correlates with Temperature: Measurement of wound area via digital planimetry revealed that reductions in wound size aligned with improvements in thermal imaging data.
• Non-Invasive Monitoring Tool: Method offers a painless, repeatable, and objective means of tracking wound progress—especially useful in settings where visual assessment is limited.
• Clinical Implications: Integrating thermal imaging with area measurement can guide treatment effectiveness, enable earlier intervention for non-healing wounds, and potentially forecast complications.

This study supports the role of thermal imaging and planimetry as valuable adjuncts in wound care, enabling data-driven monitoring that may improve outcomes for patients with chronic wounds.

Read the full article on PubMed Central.

Keywords:
thermal imaging,
planimetry,
venous leg ulcer,
non-invasive monitoring,
wound healing tracking

EWMA Releases Palliative Wound Care Guidelines: Focused on Symptom Management

The European Wound Management Association (EWMA), in collaboration with EPUAP, WHS, and Wounds Australia, has published evidence-based guidelines in the *Journal of Wound Management* (Vol 26, Suppl 1, 2025). These recommendations address the care of non-healing and palliative wounds by focusing on symptom relief rather than healing alone.

Key Highlights:

• Holistic Symptom Management: Emphasis on alleviating pain, odor, exudate, bleeding, and itch to enhance comfort and quality of life in patients with palliative wounds :contentReference[oaicite:1]{index=1}.
• Patient- and Family-Centered Care: Care plans are designed collaboratively, respecting patient preferences and involving caregivers in decision-making :contentReference[oaicite:2]{index=2}.
• Education & Multidisciplinary Approach: Guidelines recommend integrating palliative wound care principles throughout medical education and encouraging teamwork between clinicians, dietitians, psychologists, social workers, and palliative care specialists :contentReference[oaicite:3]{index=3}.
• Research & Innovation Encouraged: Highlights the need for further clinical trials and industry collaboration to develop targeted products and techniques—especially for malignancy-related wounds :contentReference[oaicite:4]{index=4}.
• Policy and Access Implications: Urges the development of institutional and national policies to ensure equitable resource access, use of telehealth, and standardized symptom-targeted protocols :contentReference[oaicite:5]{index=5}.

These guidelines reflect EWMA’s commitment to improving outcomes for patients with palliative wounds through a compassionate, evidence-based, and multidisciplinary approach, tailored to the needs of those at all stages of wound progression.

Read the full guidelines supplement in the EWMA News section and download it for free.

Keywords:
palliative wound care,
symptom management,
quality of life,
multidisciplinary care,
telehealth

Empathy in Wound Care: Mapping Its Role, Impact & Barriers

The June 2025 issue of *Wounds Practice and Research* features a scoping review protocol by Menon et al., aimed at evaluating the role of empathy in wound care practice. This study will systematically map literature on how empathy affects patient engagement, wellbeing, treatment adherence, and healing outcomes, as well as identifying barriers to its use.

Key Highlights:

• Scope & Methodology: Uses Joanna Briggs Institute and PRISMA-ScR guidelines to review studies from multiple databases (MEDLINE, CINAHL, Embase, Scopus, PsycINFO).
• Main Themes Explored: The review will consider empathy’s influence on clinician–patient rapport, pain management, psychosocial wellbeing, treatment adherence, and clinical outcomes.
• Barriers to Care: Will identify systemic and individual barriers—such as time constraints, limited training, and resource shortages—that hinder empathetic wound care.
• Anticipated Impact: Aiming to guide future education, policy, and practice by highlighting where empathy can be effectively integrated into wound care strategies.

This protocol represents an important step toward recognizing empathy as a measurable factor in wound healing and patient-centered care.

Read the full protocol in Wounds Practice and Research.

Keywords:
empathy,
scoping review,
PRISMA-ScR,
patient-centred care,
wound care

Impact of Compression Therapy on Quality of Life in Venous Leg Ulcer Patients

A randomized trial evaluated the effects of high-compression bandages and Unna’s boots on health-related quality of life (HRQoL) in patients undergoing treatment for venous leg ulcers.

Key Highlights:

• Comparative Approaches: Patients received either high-compression multilayer bandages or Unna’s boot therapy to promote ulcer healing.
• HRQoL Improvements: Both treatment groups experienced better overall quality of life, particularly with reduced pain, improved mobility, and enhanced emotional well-being. :contentReference[oaicite:1]{index=1}
• Holistic Benefits of Compression: Beyond healing, maintaining sustained compression contributed to improved daily functioning and patient comfort.
• No Major Differences Noted: Both compression methods yielded comparable results in patient-reported quality-of-life outcomes.

These outcomes underscore that effective compression therapy—whether via Unna’s boots or multilayer bandaging—benefits not only wound healing but also the broader well-being of patients living with venous leg ulcers.

Read the full article on the Wounds Practice and Research website.

Keywords:
venous leg ulcer,
compression therapy,
Unna’s boot,
quality of life,
HRQoL

The Age of Wisdom and the Age of Foolishness: A Tale of Two Wounds

In her June 11, 2025 editorial on her blog, Dr. Caroline Fife reflects on the current challenges and crossroads facing the wound care profession. She warns against complacency and urges practitioners to embrace both evidence-based wisdom and ethical courage in patient care.

Key Highlights:

• Dual Narratives: Dr. Fife contrasts moments of insightful, patient-centered innovation with instances where bureaucratic complexities and regulatory missteps undermine quality care.
• Call to Action: Emphasizes the need for clinicians to champion transparency in outcomes reporting, resist wasteful practices, and remain vigilant against policies that may compromise patient care.
• Advocacy & Leadership: Encourages wound care professionals to take active roles in shaping policies—whether in reimbursement reform, regulatory guidance, or healthcare delivery models.
• Patient-First Ethos: Underlines that true expertise lies not only in clinical knowledge but also in maintaining humility and prioritizing the patient’s voice in the face of system challenges.

Dr. Fife concludes by reminding the field that it stands at a pivotal moment—one that demands a balance of thoughtful innovation and principled action to truly honor patients and elevate professional standards.

Read the full editorial on Dr. Fife’s blog, “CarolineFifeMD.com.”

Keywords:
Caroline Fife,
professional ethics,
transparency,
patient-centered care,
wound care leadership

Optimising Ostomy Care: Matching Clinical Assessment to Convexity Characteristics

Part of the Global Innovation Summit Series and accredited for CE, this webinar (June 11, 2025) focuses on practical implementation of convexity in clinical ostomy care. Featuring evidence-based insights, case studies, and hands-on demonstrations from a landmark international evaluation, the session is designed to enhance clinicians’ ability to effectively select convex appliances.

Key Highlights:

• Evidence-Based Foundation: Insights from a multisite international prospective product evaluation involving over 1,600 patient assessments across three countries—comparing convex characteristics among 33 soft convex products.
• Clinical Assessment Skills: Learn to assess stoma features, peristomal skin integrity, and abdominal contours, identifying candidates for convex appliances and avoiding contraindications.
• Case-Based Learning: Interactive scenarios from international ostomy specialists demonstrate real-world application—highlighting fitting strategies, troubleshooting leaks, and optimizing patient comfort.
• Hands-On Product Exploration: Demonstrations of soft convex products highlighting depth, gradient, shape, and flexibility, plus guidance on common fitting issues and documentation.
• Outcome Improvement & Education: Strategies for patient-centered education, monitoring cache leakage and MASD, integrating convexity into care protocols, and aligning with quality-improvement objectives.

Watch the full free, accredited webinar on the BigMarker platform.

Keywords:
ostomy care,
convexity,
peristomal skin,
stoma assessment,
case studies

Research Roundup: Advanced Therapies for Chronic Wounds

The February 2025 issue of *Wound Care Professional* highlights three significant studies evaluating advanced biological and scaffold therapies for non-healing wounds.

Key Highlights:

• Hypothermically Stored Amniotic Membrane (HSAM) for DFUs: A multicenter retrospective series (50 patients, mean age 66.7) treated diabetic foot ulcers with HSAM and observed >60% wound area reduction in 96%, and 78% complete closure by 12 weeks (median time: 55 days).
• Dehydrated Human Amnion/Chorion Membrane (DHACM) in Venous Leg Ulcers: A cost-effectiveness analysis demonstrated that DHACM is both effective and economical for treating VLUs in Medicare populations.
• 3D Acellular Collagen Matrix in Deep/Tunnelling DFUs: Retrospective case series showed promising tissue fill and wound contraction results using collagen scaffold in complex diabetic foot ulcers.

These findings reinforce the potential of amniotic and collagen-derived biological scaffolds to enhance healing in persistent chronic wounds, while also addressing cost considerations in clinical practice.

Access the full *Research Roundup* in the Wound Care Professional (Vol 4 Issue 1, Feb 2025).

Keywords:
hypothermic amniotic membrane,
dehydrated amnion/chorion membrane,
3D collagen matrix,
diabetic foot ulcer,
venous leg ulcer

Topical Pentoxifylline 10% Gel Accelerates Healing in Pressure Ulcers

A randomized controlled trial, published online June 3, 2025 in *International Journal of Low Extremity Wounds*, evaluated the effectiveness of a 10% pentoxifylline (PTX) topical gel versus standard care in 70 patients with stage 2–3 pressure ulcers.

Key Highlights:

• Study Design: 35 patients received PTX gel once daily plus standard care; 35 in control group received standard care with an alternative novel dressing.
• Wound Size Reduction: The PTX group showed a significantly greater decrease in ulcer area at both week 1 and week 2 (p < 0.05).
• Complete Healing: By week 2, 46% of the PTX group achieved complete wound closure compared to 26% in the control group (45.7% vs 25.7%; p = 0.081), just missing statistical significance.
• Conclusion: Topical PTX 10% gel appears to safely and effectively enhance early healing in pressure ulcers, offering a promising local treatment strategy.

Read the full article in Int J Low Extrem Wounds.

Keywords:
pentoxifylline,
topical gel,
pressure ulcer,
randomized controlled trial,
wound healing

Using Patient‑Reported Experiences to Guide Foam Dressing Use in Hard‑to‑Heal Wounds

A review led by Kevin Woo and co-authors, published in *Journal of Wound Care* (Nov 2024), highlights the importance of incorporating patient-reported outcomes—such as pain, odor, itch, drainage, and self-care capabilities—when selecting foam dressings for chronic wounds. The expert panel calls for greater collaboration across clinical, research, and industry sectors to address these needs.

Key Highlights:

• Holistic Dressing Selection: Foam dressing choice must balance wound characteristics with patient experiences to improve quality of life and adherence. :contentReference[oaicite:1]{index=1}
• Identified Outcome Domains: The review identifies five core categories—wound-related pain, odor, itch, exudate volume, and self-management capacity—as critical to patient-centered care. :contentReference[oaicite:2]{index=2}
• Accountability Across Sectors: Authors urge clinicians, researchers, and industry to adopt shared responsibility in designing dressings that meet both clinical efficacy and patient comfort metrics. :contentReference[oaicite:3]{index=3}
• Population Impact: Hard-to-heal wounds affect approximately 1.67 per 1000 people globally and impose significant health and economic burdens. :contentReference[oaicite:4]{index=4}

By centering patient-reported experiences in product evaluation and development, this review promotes more person-focused wound care strategies and improved outcomes.

Read the full article in the Journal of Wound Care (via Wound Central).

Keywords:
patient-reported experience,
foam dressings,
hard‑to‑heal wounds,
wound‑related pain,
self‑management

Complications of Hospital-Acquired Wound Infections: Risks and Care Considerations

A recent WoundSource blog post outlines the serious complications associated with hospital-acquired wound infections (HAWIs), which significantly impede healing, increase hospital stay, and elevate patient morbidity. These infections often emerge in surgical wounds, pressure injuries, and device-related sites. :contentReference[oaicite:turn0search0]{index=0}

Key Highlights:

• Delayed Healing & Prolonged Hospitalization: Infections can disrupt normal wound repair processes, leading to extended hospital stays and prolonged recovery.
• Abscess Formation: Localized collections of pus may develop, requiring incision, drainage, and targeted antimicrobial therapy. :contentReference[oaicite:turn0search0]{index=0}
• Surgical Wound Dehiscence: Infection can cause wound edges to separate prematurely, necessitating additional surgical or mechanical closure interventions. :contentReference[oaicite:turn0search2]{index=0}
• Antimicrobial Resistance & Sepsis Risk: Hospital-acquired pathogens often exhibit multidrug resistance, complicating treatment and raising the risk of systemic infection and sepsis.

This overview emphasizes that early recognition, appropriate dressing selection, and prompt antimicrobial therapy are critical to minimizing complications associated with hospital-acquired wound infections.

Read the full article on the WoundSource website.

Keywords:
hospital-acquired infection,
wound complications,
abscess,
dehiscence,
antimicrobial resistance

Outcome Measures of Quality of Life for People With Chronic Wounds: A Scoping Review

A scoping review published in *JWOCN* (May–June 2025) by Dantas et al. mapped validated patient-reported outcome measures (PROMs) used to assess health-related quality of life (HRQoL) in individuals with chronic wounds. :contentReference[oaicite:turn0search0]{index=0}

Key Highlights:

• Review Scope: Surveyed literature from 1990 to April 2024 across MEDLINE, CINAHL, PubMed, Web of Science, and Scopus, identifying 30 studies evaluating HRQoL in chronic wound patients. :contentReference[oaicite:turn0search0]{index=0}
• Instruments Identified: Twelve validated tools were used—six generic (e.g., SF-36 in 19%, EQ-5D-5L in 9%) and six wound-specific. Notably, the Cardiff Wound Impact Schedule and Wound‑QoL each appeared in 16% of studies. :contentReference[oaicite:turn0search0]{index=0}
• Instrument Benefits: Generic measures allow comparisons with other chronic conditions and populations, but may underrepresent wound-specific QoL changes. Wound-specific instruments capture the multidimensional impacts on patients’ lives more sensitively. :contentReference[oaicite:turn0search0]{index=0}
• Research Gaps: The review highlights limited use of PROMs in chronic wound studies, calling for more longitudinal and interventional research to validate their clinical utility. :contentReference[oaicite:turn0search0]{index=0}

Understanding which PROMs reliably capture HRQoL among patients with chronic wounds is essential for patient-centered care, enabling better assessment of therapeutic impact and guiding future investigations.

Read the full abstract in the Journal of Wound Ostomy & Continence Nursing.

Keywords:
PROMs,
HRQoL,
SF-36,
EQ-5D-5L,
Wound‑QoL

Top‑Ten Tips for Preventing and Treating Skin Tears

Skin tears are common in older adults due to thinning skin and loss of elasticity. Wounds International outlines ten practical strategies aimed at prevention, early recognition, and effective management. :contentReference[oaicite:turn0search0]{index=0}

Key Highlights:

• 1. Prioritize Prevention: Understand that aged skin is fragile—fragile skin is more prone to tearing. Early, proactive strategies are essential. :contentReference[oaicite:turn0search0]{index=0}
• 2. Maintain Skin Hydration: Regular use of fragrance‑free, hypoallergenic moisturizers preserves skin elasticity, reducing tear risk. :contentReference[oaicite:turn0search0]{index=0}
• 3. Choose Cost‑Effective Silicone Dressings: Silicone contact layers or foam dressings are preferred—they support healing, protect during removal, and minimize trauma. :contentReference[oaicite:turn0search4]{index=0}
• 4. Use ISTAP Best Practices: Re‑approximate skin flaps gently, avoid stretching, cleanse properly, balance moisture, and limit infection. These are foundational principles. :contentReference[oaicite:turn0search4]{index=0}
• 5. Educate Staff and Patients: Training to identify, classify, and manage skin tears fosters consistent, evidence‑based care. :contentReference[oaicite:turn0search4]{index=0}
• 6. Document and Classify Tears: Use the ISTAP type I/II/III system (no flap loss, partial flap loss, total flap loss) and implement decision algorithms promptly. :contentReference[oaicite:turn0search9]{index=0}
• 7. Preserve Skin Flaps: Whenever possible, reposition viable skin back into place to encourage natural healing. :contentReference[oaicite:turn0search9]{index=0}
• 8. Secure Flaps Without Adhesives: Use silicone dressings or gentle bandaging methods to anchor skin without trauma. :contentReference[oaicite:turn0search4]{index=0}
• 9. Monitor Exudate and Contamination: Control fluid balance and look out for signs of infection or deteriorating wound edges. :contentReference[oaicite:turn0search4]{index=0}
• 10. Incorporate Flap‑Friendly Dressings in Protocols: Avoid adhesives, hydrocolloids, and gauze; prefer silicone-based products to support healing and reduce trauma. :contentReference[oaicite:turn0search4]{index=0}

Integrating these tenets into education and care pathways—alongside tools like the ISTAP Decision‑Classification guide—can significantly reduce incidence, distress, and treatment costs associated with skin tears. :contentReference[oaicite:turn0search5]{index=0}

Read the full article on the Wounds International website.

Keywords:
skin tears,
ISTAP,
silicone dressings,
moisturizers,
skin tear prevention

Foot Ulceration Following Unintentional Xylazine Injection

A case report by Eric Kaplan, DPM, and Jacob Kaplan highlights a foot ulcer resulting from inadvertent xylazine exposure during illicit drug use. Xylazine, an alpha-2 agonist increasingly found in unregulated opioid supplies, causes local vasoconstriction leading to tissue necrosis and ulceration. :contentReference[oaicite:turn0search0]{index=0}

Key Highlights:

• Initial Presentation: A patient developed redness, warmth, and edema near injection sites, progressing to a heterogeneous lesion measuring approximately 3.3 cm² on ultrasound, along with tenosynovitis on MRI. Intravenous antibiotics (vancomycin, piperacillin/tazobactam, then cefazolin) were administered. :contentReference[oaicite:turn0search0]{index=0}
• Ulcer Formation: Five days post-discharge, the patient returned with a foul‑smelling, necrotic, draining ulcer (~3 cm²) reaching to the mid-calf, necessitating hospital readmission and broad‑spectrum IV antibiotics. :contentReference[oaicite:turn0search0]{index=0}
• Xylazine Detection: Drug testing revealed that the patient’s supply of heroin/cocaine contained xylazine (“Tranq”), confirming the cause of the ulcer based on vasoconstrictive skin effects. :contentReference[oaicite:turn0search0]{index=0}
• Treatment Course: Management included sharp debridement down to the tibialis anterior tendon, xeroform dressing, and a transition to oral antibiotics (amoxicillin/clavulanate plus trimethoprim-sulfamethoxazole) post‑hospitalization. :contentReference[oaicite:turn0search0]{index=0}
• Clinical Conclusion: Xylazine-induced necrosis presents unique challenges due to unknown drug interactions and requires aggressive antimicrobial therapy paired with surgical debridement. The authors call for further research to understand underlying mechanisms and refine treatment protocols. :contentReference[oaicite:turn0search0]{index=0}

This case underscores the emerging threat of xylazine in unregulated drug supplies and emphasizes the need for awareness among clinicians managing foot ulcerations in this population.

Read the full case report on the HMP Global Learning Network (Podiatry Today).

Keywords:
xylazine ulceration,
alpha‑2 agonist,
drug injection ulcer,
sharp debridement,
necrotic ulceration

47th Annual Seattle Summer Seminar on Foot & Ankle Care

The International Foot & Ankle Foundation (IFAF) is hosting its 47th Annual Seattle Summer Seminar from June 26–28, 2025, at Swedish Medical Center – Cherry Hill Campus, Seattle, WA. This premier event offers up to 20 continuing education credit hours (CECH), including radiology credits, and combines expert lectures with hands‑on workshops focused on lower extremity musculoskeletal conditions and skin problems in foot and ankle practice.

Key Highlights:

• Date & Location: June 26–28, 2025 at Swedish Medical Center – Cherry Hill Campus, Seattle, WA :contentReference[oaicite:1]{index=1}
• Education Credits: Up to 20 CECH available, including radiology-specific credit :contentReference[oaicite:2]{index=2}.
• Lecture & Workshop Topics: Forefoot reconstruction, lower‑extremity musculoskeletal conditions, common skin issues in foot surgery, and management of postoperative complications :contentReference[oaicite:3]{index=3}.
• Format: A combination of in-depth lectures and practical skills workshops, with a Friday evening hands‑on session for interactive learning :contentReference[oaicite:4]{index=4}.
• Audience: Designed for podiatrists, surgeons, and allied health professionals seeking the latest clinical knowledge and hands‑on skill development.

Learn more and register on the International Foot & Ankle Foundation website.

Keywords:
Seattle Summer Seminar,
continuing education,
forefoot reconstruction,
lower extremity musculoskeletal,
foot surgery complications

An Opportunity to Learn More About Lymphoedema and Related Conditions

In an editorial for Wound Care Today, Christine Moffatt and Melanie Thomas (MBE) highlight lymphoedema as a chronic, progressive condition affecting patients both physically and psychologically. Despite being incurable, effective management is essential to prevent deterioration and preserve quality of life. :contentReference[oaicite:turn0search0]{index=0}

Key Highlights:

• International Lymphoedema Framework (ILF): A charity advancing evidence-based care globally through 17 national frameworks, combining clinical, scientific, and technical expertise.
• Ethical Independence: ILF’s charitable structure ensures resource use remains transparent and focused on patient benefit.
• “Stronger Together” Conference: The 11th ILF conference (June 13–15, 2025, Nottingham) will unite global experts to share research, skills, and innovations in lymphoedema and related disorders.
• Patient Engagement: Includes a dedicated patient day on June 15, providing education on cellulitis management, living well with lymphoedema, and expert Q&A sessions.
• Holistic Goals: Conference aims to empower professionals to deliver efficient, evidence-based, and non-wasteful care, while raising lymphoedema’s profile within healthcare systems.

The editorial underscores the importance of collaborative global efforts to elevate lymphoedema care, supporting both clinicians and patients through shared learning and advocacy. :contentReference[oaicite:turn0search0]{index=0}

Read the full editorial on the Wound Care Today website.

Keywords:
lymphoedema,
International Lymphoedema Framework,
patient education,
professional conference,
non‑wasteful care

Dehydrated Human Amnion Membrane Plus Standard Care in Non‑Healing Diabetic Foot Ulcers

A multicenter randomized controlled trial (AXOCAMP; NCT06550596), led by Axolotl Biologix and launched on September 23, 2024, is recruiting adults with non‑healing Wagner grade 1 or 2 diabetic foot ulcers (1–5 cm²) persisting for ≥4 weeks to evaluate whether adding a dehydrated human amnion membrane (dhAM; Axolotl DualGraft) to standard of care (SOC) accelerates healing compared to SOC alone. :contentReference[oaicite:0]{index=0}

Key Highlights:

• Population & Design: Up to 100 participants (age ≥18, Type 1 or 2 diabetes) with adequate limb perfusion (ABI 0.7–1.3, TBI ≥0.6, or TCOM ≥40 mmHg) and ulcer duration 4–52 weeks. Randomized parallel groups. :contentReference[oaicite:0]{index=0}
• Interventions: Experimental arm receives weekly Axolotl DualGraft (dhAM) applications plus SOC (offloading, debridement, moisture balance); control arm receives SOC alone. :contentReference[oaicite:0]{index=0}
• Endpoints & Monitoring: Primary endpoint is wound closure; assessments occur weekly. Eligibility excludes infected, osteomyelitic ulcers, immunosuppressed individuals, malnourished, pregnant, or severely comorbid patients. :contentReference[oaicite:0]{index=0}
• Timeline: Recruiting as of January 28, 2025; Target completion date: October 31, 2025. :contentReference[oaicite:0]{index=0}

Read the full trial registration on ClinicalTrials.gov.

Keywords:
dehydrated human amnion membrane,
diabetic foot ulcer,
standard of care,
Axolotl DualGraft,
clinical trial

Dr. Jay Shah Launches “Let Doctors Be Doctors” Podcast as TMA President

Dr. Jay Shah, a distinguished wound care specialist, has been appointed President of the Texas Medical Association (TMA). In his new role, he has initiated the podcast “Let Doctors Be Doctors”, aiming to delve into the personal and professional journeys of Texas physicians. The podcast addresses challenges in the medical field, including physician burnout and moral injury, fostering a platform for open dialogue and shared experiences. Read the full article.

Key Highlights:

• Leadership in Medicine: Dr. Shah’s presidency at TMA marks a significant milestone, bringing a wound care practitioner’s perspective to a prominent leadership position.
• Podcast Objectives: “Let Doctors Be Doctors” seeks to humanize the medical profession by sharing physicians’ stories, challenges, and coping mechanisms, particularly focusing on issues like moral injury and burnout.
• Community Engagement: The podcast serves as a conduit for community building among medical professionals, encouraging conversations that can lead to systemic improvements in healthcare.

Dr. Caroline Fife, a renowned wound care physician, expressed her enthusiasm for Dr. Shah’s new venture, highlighting the importance of such initiatives in promoting physician well-being and patient care excellence.

Read the full article on the Caroline Fife, M.D. website.

Keywords:
Jay Shah,
Texas Medical Association,
physician burnout,
moral injury,
medical leadership

Continuous Topical Oxygen Therapy Enhances Healing in Chronic Wounds: A Colombian Study

A recent study published in the Journal of Wound Care evaluates the efficacy of continuous topical oxygen therapy (cTOT) in managing hard-to-heal or chronic wounds in Colombia. The research indicates that cTOT may offer significant advantages over traditional treatments in promoting wound healing and reducing associated pain. Read the full article.

Key Highlights:

• Objective: To assess the effectiveness of cTOT in accelerating the healing process of chronic wounds and alleviating pain in patients.
• Findings: The study suggests that patients receiving cTOT experienced improved wound healing rates and reduced pain levels compared to those undergoing traditional treatment methods.
• Clinical Implications: These results support the integration of cTOT into standard wound care practices, particularly for patients with chronic wounds that are resistant to conventional therapies.

This study underscores the potential of cTOT as a valuable tool in the management of chronic wounds, offering benefits in both healing efficacy and patient comfort.

Read the full article on the Journal of Wound Care website.

Keywords:
continuous topical oxygen therapy,
chronic wounds,
wound healing,
pain management,
Colombia wound care

Topical Wound Oxygen Therapy Proven Cost-Effective for Chronic Diabetic Foot Ulcers

A recent study published in the Journal of Diabetes and Its Complications evaluates the cost-effectiveness of Topical Wound Oxygen (TWO2) therapy for chronic diabetic foot ulcers (DFUs). Utilizing a Markov model over a two-year horizon, the research assesses both economic and clinical outcomes associated with TWO2 therapy compared to standard care. Read the full article.

Key Highlights:

• Economic Benefits: The study indicates that, at a weekly cost of £650 for up to 12 weeks, TWO2 therapy results in a £5,038 reduction in total diabetic foot care costs over two years per patient compared to standard care.
• Improved Health Outcomes: Patients receiving TWO2 therapy experienced an increase of 0.07 quality-adjusted life years (QALYs) over the two-year period.
• High Probability of Cost-Effectiveness: Probabilistic sensitivity analysis reveals an 81% likelihood that TWO2 therapy is cost-effective at a willingness-to-pay threshold of £25,000 per QALY.
• Clinical Efficacy: The model’s clinical inputs are derived from a multinational randomized controlled trial demonstrating superior healing rates with TWO2 therapy.
• Global Health Implications: Given the substantial burden of DFUs worldwide, the adoption of cost-effective treatments like TWO2 therapy could significantly reduce healthcare expenditures and improve patient quality of life.

This study underscores the potential of TWO2 therapy not only to enhance clinical outcomes for patients with chronic DFUs but also to provide significant cost savings for healthcare systems.

Read the full article on the Advanced Oxygen Therapy Inc. website.

Keywords:
Topical Wound Oxygen Therapy,
diabetic foot ulcers,
cost-effectiveness,
quality-adjusted life years,
health economics

ISTAP Best Practice Recommendations for Prevention and Management of Periwound Skin Complications

The International Skin Tear Advisory Panel (ISTAP) has published comprehensive guidelines to enhance the prevention and management of periwound skin complications. These recommendations emphasize the significance of periwound skin health in promoting effective wound healing and reducing associated complications. Read the full document.

Key Highlights:

• Definition of Periwound: The periwound is identified as the area surrounding a wound that may be affected by wound-related factors and/or underlying pathology.
• Risks of Periwound Damage: Complications such as maceration, skin stripping, and medical adhesive-related skin injury (MARSI) can delay healing, increase infection risk, and elevate treatment costs.
• Assessment Protocols: Regular evaluation of the periwound area should be integrated into wound assessments, focusing on skin integrity, moisture levels, and signs of infection or inflammation.
• Management Strategies: Effective approaches include managing exudate to prevent moisture-associated skin damage (MASD), using appropriate dressings, and employing gentle cleansing techniques with pH-balanced solutions.
• Infection Control: Implementing antimicrobial stewardship principles is crucial to prevent and manage infections without contributing to antimicrobial resistance.
• Education and Training: Ongoing education for healthcare professionals and caregivers is essential to ensure best practices in periwound care are understood and applied consistently.

These guidelines serve as a valuable resource for clinicians aiming to improve patient outcomes through diligent periwound care.

Read the full document on the Wounds International website.

Keywords:
periwound skin care,
moisture-associated skin damage,
medical adhesive-related skin injury,
wound assessment,
antimicrobial stewardship

Comprehensive Strategies for Managing Periwound Dermatitis in Chronic Wounds

Periwound dermatitis, an inflammatory condition affecting the skin surrounding chronic wounds, poses significant challenges to effective wound healing. Characterized by symptoms such as redness, itching, and discomfort, this condition often arises from factors like excessive wound exudate and irritants from dressings. Read the full article.

Key Highlights:

• Understanding Periwound Dermatitis: This condition is commonly a form of contact dermatitis, either allergic or irritant, frequently resulting from exposure to wound exudate or components of wound dressings. It is often classified under moisture-associated skin damage (MASD).
• Risk Factors: Factors contributing to periwound dermatitis include advanced age, comorbidities like venous insufficiency, nutritional deficiencies, and a history of skin disorders. These elements can compromise skin integrity, making it more susceptible to inflammation and damage.
• Clinical Assessment: Regular evaluation of the periwound area is crucial. Clinicians should look for signs such as erythema, increased skin temperature, and patient-reported symptoms like itching or burning sensations. It’s important to note that skin changes may present differently across various skin tones.
• Management Strategies: Effective management involves:
  • Removal of Irritants: Identifying and eliminating the causative agents, such as switching to hypoallergenic dressings or using normal saline instead of potential irritant cleansers.
  • Skin Protection: Applying barrier creams like zinc paste or petrolatum to shield the skin from further irritation.
  • Exudate Management: Utilizing appropriate absorbent dressings to control excessive wound exudate, thereby reducing moisture-related skin damage.
  • Pharmacological Interventions: In cases of significant inflammation, topical corticosteroids or antihistamines may be prescribed to alleviate symptoms.
• Patient Education: Educating patients on proper wound care practices, including gentle cleansing techniques and the importance of adhering to treatment plans, is vital for preventing recurrence and promoting healing.

Addressing periwound dermatitis requires a multifaceted approach that combines careful assessment, targeted interventions, and patient involvement to enhance healing outcomes and improve quality of life.

Read the full article on the The Wound Pros website.

Keywords:
periwound dermatitis,
moisture-associated skin damage,
contact dermatitis,
wound exudate management,
skin barrier protection

Periwound Skin: Understanding and Managing the Skin Surrounding Wounds

Proper care of the periwound skin—the area extending approximately 1.5 inches from the wound edge—is essential for effective wound healing. This delicate skin is susceptible to damage from moisture, adhesives, and infection, which can impede the healing process. Read the full article.

Key Highlights:

• Moisture-Associated Skin Damage (MASD): Excessive wound exudate can lead to maceration, causing redness, irritation, and pain in the periwound area. Managing moisture levels is crucial to prevent skin breakdown.
• Medical Adhesive-Related Skin Injury (MARSI): Improper application or removal of wound dressings can strip the skin, leading to MARSI. Over 25% of post-surgical patients experience MARSI in the periwound region.
• Signs of Periwound Complications: Indicators include induration (hardening), erythema (redness), swelling, bruising, red streaks emanating from the wound, fever, or general malaise.
• Prevention Strategies:
  • Gently clean the periwound area during each dressing change.
  • Use barrier creams like petroleum jelly to protect against moisture.
  • Minimize dressing changes to those recommended by healthcare providers.
  • Carefully remove adhesives by pressing down on the skin beneath to reduce trauma.
  • Regularly assess the periwound area for any changes or signs of damage.
• Treatment Approaches: Addressing periwound skin damage involves preventing further injury and promoting healing. This may include repositioning bandages, using barrier creams, and consulting healthcare providers for tailored care plans.

Maintaining the integrity of the periwound skin is vital for optimal wound healing. Incorporating periwound care into the overall wound management plan can enhance patient outcomes and reduce complications.

Read the full article on the Verywell Health website.

Keywords:
periwound skin,
moisture-associated skin damage,
medical adhesive-related skin injury,
wound healing,
barrier creams

Autofluorescence Imaging Enhances Detection of Bacterial Burden in Wounds

A recent study published in Advances in Wound Care investigates the clinical utility of autofluorescence imaging for identifying significant bacterial loads in chronic wounds. The research demonstrates that fluorescence-guided wound care can improve the detection of bacterial burden, leading to more targeted and effective treatment strategies. Read the full article.

Key Highlights:

• Enhanced Bacterial Detection: Autofluorescence imaging enables clinicians to visualize bacterial presence in wounds by emitting fluorescence signals, allowing for more accurate identification of infection-prone areas.
• Improved Treatment Outcomes: Utilizing fluorescence-guided assessments can lead to more precise debridement and antimicrobial interventions, potentially accelerating wound healing and reducing complications.
• Non-Invasive Technique: This imaging method offers a non-invasive approach to assess bacterial burden, minimizing patient discomfort and the need for invasive sampling procedures.
• Clinical Implications: Incorporating autofluorescence imaging into routine wound assessments may enhance clinical decision-making, optimize treatment plans, and improve overall patient outcomes.

This study underscores the potential of autofluorescence imaging as a valuable tool in the management of chronic wounds, offering a more accurate and patient-friendly method for detecting bacterial infections.

Read the full article on the PubMed Central website.

Keywords:
autofluorescence imaging,
bacterial burden,
chronic wounds,
fluorescence-guided wound care,
non-invasive diagnostics

Enzymatic Debridement Outperforms Autolytic Methods in Treating Severe Wounds

A recent systematic review published in Dermatology Times highlights the superior efficacy of enzymatic debridement over autolytic methods for managing severe chronic wounds. The analysis encompassed five studies involving 236 patients with conditions such as diabetic foot ulcers, pressure ulcers, venous leg ulcers, and post-traumatic burn wounds. Read the full article.

Key Highlights:

• Accelerated Wound Healing: Enzymatic debridement achieved a 65% reduction in wound size, compared to 50% with autolytic methods, indicating a statistically significant improvement in healing rates.
• Enhanced Tissue Regeneration: Patients treated with enzymatic agents exhibited higher rates of granulation tissue formation and epithelialization, leading to quicker wound closure.
• Higher Complete Healing Rates: Approximately 65% of patients undergoing enzymatic debridement experienced complete healing, versus 50% in the autolytic group.
• Safety Profile: Both methods were well tolerated, with mild irritation being the most common adverse effect reported in the enzymatic debridement group.
• Clinical Recommendations: While autolytic debridement remains suitable for non-severe wounds due to its non-invasive nature, enzymatic debridement is recommended for severe wounds requiring faster and more effective tissue removal.

This review underscores the importance of selecting appropriate debridement techniques based on wound severity to optimize healing outcomes and patient care.

Read the full article on the Dermatology Times website.

Keywords:
enzymatic debridement,
autolytic debridement,
chronic wounds,
wound healing,
collagenase

Alliance Advocates for Deregulation to Enhance Wound Care Access and Efficiency

On May 12, 2025, the Alliance of Wound Care Stakeholders submitted comprehensive comments to the Office of Management and Budget (OMB), responding to a federal request for feedback on opportunities for deregulation. The Alliance’s recommendations aim to streamline regulatory processes, reduce administrative burdens, and improve patient access to essential wound care treatments. Read the full article.

Key Highlights:

• Opposition to FDA Reclassification: The Alliance urges the withdrawal of the FDA’s proposed rule to reclassify certain antimicrobial wound dressings, citing concerns over reduced product availability and potential negative impacts on patient care.
• Prior Authorization Reforms: Recommendations include simplifying prior authorization processes to alleviate delays and administrative burdens for both providers and patients.
• Medicare Therapeutic Shoe Program Adjustments: The Alliance suggests reducing complexities within this program to enhance access for diabetic patients requiring therapeutic footwear.
• Payment Provision Corrections: Calls for rectifying problematic payment structures for Cellular and/or Tissue-based Products (CTPs) within the Hospital Outpatient Prospective Payment System to ensure fair reimbursement.
• Emphasis on Real-World Evidence (RWE): Advocates for the expanded adoption of RWE in coverage determinations and updates to the Coverage with Evidence Development framework.
• Administrative Simplification: Proposes reforms to the National Correct Coding Initiative, audit procedures, and data reporting processes to eliminate duplicative or overly complex requirements.

These targeted recommendations reflect the Alliance’s commitment to fostering a regulatory environment that supports efficient, patient-centered wound care practices.

Read the full article on the Alliance of Wound Care Stakeholders website.

Keywords:
wound care regulation,
prior authorization,
therapeutic shoe program,
real-world evidence,
Medicare payment policy

Editorial Insight: Exploring the Motivations Behind Medical Publishing

In the May 2025 editorial of Wounds, Editor-in-Chief Dr. John C. Lantis II delves into the multifaceted reasons why clinicians and researchers choose to publish their work. While the altruistic aim of sharing knowledge to benefit patient care is often cited, Dr. Lantis acknowledges that various other motivations drive the publication process. Read the full article.

Key Highlights:

• Product Support: A prevalent reason for publication is to endorse the use of specific products in treating common diseases, a trend amplified by recent governmental regulations. This has led to increased literature on managing pressure injuries, atypical wounds, and post-surgical complications.
• Academic Advancement: The “publish or perish” culture in academia motivates individuals at all career stages to contribute to scientific literature. Notably, even high school students have been recognized for their research contributions, highlighting the broad spectrum of academic involvement.
• Clinical Protocol Development: Publishing can stem from the desire to share effective care algorithms developed through clinical experience, offering valuable insights into successful treatment protocols.
• Understanding Negative Outcomes: Documenting studies with unfavorable results is crucial, as they provide insights into disease progression and inform future research directions, especially in areas like critical limb ischemia and venous leg disease.
• Industry Collaboration: Collaborations between clinicians and industry partners can yield comprehensive consensus documents, combining practical experience with in-depth knowledge of therapeutic mechanisms.

Dr. Lantis emphasizes the importance of transparency regarding one’s motivations for publishing. Recognizing and understanding these drivers can enhance the integrity and impact of scientific contributions.

Read the full editorial on the HMP Global Learning Network website.

Keywords:
medical publishing,
academic advancement,
clinical research,
product support,
industry collaboration

Today’s Wound Clinic Evolves into Wound Care Business Navigator

After 18 years of serving the wound care community, Today’s Wound Clinic (TWC) is transitioning into the Wound Care Business Navigator (WCBN), a dynamic digital platform designed to meet the evolving needs of modern wound care professionals. This change reflects the growing demand for comprehensive, real-time resources that address the complexities of reimbursement, compliance, and operational efficiency in wound care practice. Read the full article.

Key Highlights:

• Purpose-Driven Transition: WCBN is designed to provide clinicians with immediate access to expert insights, regulatory updates, and practical tools to navigate the complexities of wound care business operations.
• Interactive and Adaptive Platform: Unlike traditional publications, WCBN offers a continuously updated, interactive experience that evolves alongside industry changes, ensuring users have the most current information at their fingertips.
• Comprehensive Resource Hub: The platform aims to centralize critical information, addressing common challenges such as fragmented knowledge, revenue leakage, compliance risks, and operational inefficiencies.
• Expert Leadership: Dr. Caroline E. Fife, who has been instrumental in TWC’s success, continues to contribute her expertise, ensuring that WCBN maintains the high standards and relevance that readers have come to expect.

This strategic evolution signifies a commitment to empowering wound care professionals with the resources needed to optimize patient care and practice management in a rapidly changing healthcare landscape.

Read the full article on the HMP Global Learning Network website.

Keywords:
Wound Care Business Navigator,
Today’s Wound Clinic,
wound care reimbursement,
practice management,
regulatory compliance

Understanding Transparent Film Dressings: Applications and Best Practices

Transparent film dressings are thin, adhesive-coated polyurethane sheets designed to provide a moist healing environment, promote autolytic debridement, and protect wounds from mechanical trauma and bacterial invasion. Their flexibility allows them to conform to various body contours, making them suitable for wounds in challenging locations like elbows and heels. The transparency of these dressings enables easy visualization of the wound bed without removal, facilitating ongoing assessment. Read the full article.

Key Highlights:

• Moist Healing Environment: These dressings maintain a moist environment conducive to wound healing and support autolytic debridement by allowing the body’s own enzymes to break down necrotic tissue.
• Barrier Protection: They are waterproof and impermeable to bacteria and contaminants, yet permeable to moisture vapor and gases, facilitating gas exchange while protecting the wound.
• Versatile Applications: Ideal for partial-thickness wounds with minimal drainage, protection of intact skin (e.g., over bony prominences), securing IV catheters, and as secondary dressings over other wound care products.
• Application Considerations: Proper application involves ensuring the skin is clean and dry, applying a moisture barrier to the periwound area, and avoiding stretching the dressing during placement to prevent tension that could lead to skin damage.
• Precautions: Not recommended for wounds with moderate to heavy exudate, third-degree burns, suspected or active infections, or in patients with fragile skin, as removal may cause skin stripping or tears.

Transparent film dressings are a valuable tool in wound care management, offering protection and promoting healing in suitable wound types. Proper selection and application are crucial to maximize their benefits and minimize potential complications.

Read the full article on the Wound Care Advisor website.

Keywords:
transparent film dressings,
autolytic debridement,
wound healing,
moist wound environment,
periwound skin protection

Jingfang Granules Show Promise in Accelerating Diabetic Wound Healing

A recent study published in Drug Design, Development and Therapy investigates the therapeutic potential of Jingfang Granules (JFG), a traditional Chinese medicine formulation, in promoting diabetic wound healing. Utilizing a combination of network pharmacology and experimental validation, the research aims to elucidate the mechanisms by which JFG may enhance wound repair in diabetic conditions. Read the full article.

Key Highlights:

• Multi-Component Analysis: Network pharmacology identified multiple active compounds within JFG that target key proteins involved in wound healing processes, including inflammation modulation and tissue regeneration.
• Pathway Enrichment: The analysis revealed that JFG influences several critical signaling pathways, such as the PI3K-Akt and MAPK pathways, which are integral to cell proliferation and angiogenesis.
• Experimental Validation: In vivo experiments demonstrated that JFG treatment significantly accelerated wound closure in diabetic rat models, corroborating the computational predictions.
• Anti-Inflammatory Effects: JFG administration resulted in reduced expression of pro-inflammatory cytokines, suggesting its role in mitigating chronic inflammation associated with diabetic wounds.

This integrative study underscores the potential of Jingfang Granules as a complementary therapeutic approach for enhancing diabetic wound healing, warranting further clinical investigations.

Read the full article on the Dove Medical Press website.

Keywords:
Jingfang Granules,
diabetic wound healing,
network pharmacology,
traditional Chinese medicine,
PI3K-Akt pathway

Innovative Silicone-Acrylic Drape Enhances NPWT Outcomes in Patients with Periwound Skin Breakdown

A recent case series published in Wounds journal explores the use of a novel silicone-acrylic hybrid drape (HA-drape) in conjunction with negative pressure wound therapy (NPWT) to address periwound skin breakdown. The study involved four patients who developed mild to moderate periwound skin irritation during standard NPWT. Transitioning to the HA-drape aimed to minimize skin damage while maintaining effective wound sealing. Read the full article.

Key Highlights:

• Enhanced Patient Comfort: All patients reported decreased pain during dressing removal after switching to the HA-drape, attributed to its gentler adhesion properties.
• Improved Periwound Skin Integrity: Significant improvement in periwound skin condition was observed after the first dressing change using the HA-drape.
• Effective Seal Maintenance: The HA-drape maintained a reliable negative pressure seal throughout treatment, comparable to traditional drapes.
• Repositionable Design: The hybrid drape allowed for repositioning during application, facilitating better fit and reducing the need for ancillary sealing products.

This study suggests that the silicone-acrylic hybrid drape may offer a beneficial alternative for patients experiencing periwound skin complications during NPWT, enhancing comfort and potentially improving healing outcomes.

Read the full article on the HMP Global Learning Network website.

Keywords:
negative pressure wound therapy,
silicone-acrylic drape,
periwound skin breakdown,
wound healing,
medical adhesive-related skin injury

Electrospun Polymer Mats for Controlled Drug Delivery in Wound Care

Researchers at the Henryk Niewodniczański Institute of Nuclear Physics of the Polish Academy of Sciences (IFJ PAN) have developed electrospun polymer mats embedded with the antibacterial agent metronidazole, aiming to enhance wound healing through localized and controlled drug release. :contentReference[oaicite:2]{index=2}:contentReference[oaicite:3]{index=3}

Key Highlights:

• Electrospinning Technique: Utilizing electrospinning, a method that creates fine polymer fibers through an electrostatic field, the team produced mats capable of delivering drugs directly to wound sites.
• Controlled Drug Release: The mats are designed to release metronidazole gradually over several hours, ensuring sustained antibacterial action while minimizing systemic exposure.
• Structural Design: Two types of fiber structures were developed: homogeneous fibers and core-shell fibers, the latter using a coaxial needle to encapsulate the drug within a protective polymer shell.
• Optimal Fiber Dimensions: Studies determined that fiber diameters between 0.7 and 1.3 micrometers provide an adequate surface area for effective drug absorption and release.
• Storage Considerations: The mats can be stored for up to one month before application, after which the metronidazole may begin to crystallize, potentially affecting efficacy.

This innovative approach to wound care highlights the potential of electrospun polymer mats in delivering targeted therapy, reducing the risk of systemic side effects, and improving patient outcomes. The researchers suggest that this method could be adapted to carry other therapeutic agents, broadening its applicability in medical treatments. :contentReference[oaicite:18]{index=18}:contentReference[oaicite:19]{index=19}

Read the full article on the EurekAlert! website.

Keywords:
electrospinning,
polymer mats,
metronidazole,
wound healing,
controlled drug release

Sole Purpose 61: Embracing the Pain—Lessons in Resilience from Stoicism, Residency, and Running

In the latest installment of the Sole Purpose series, Dr. Santiago delves into the intertwined themes of physical and mental endurance, drawing parallels between the rigors of medical residency, the discipline of long-distance running, and the philosophical tenets of Stoicism. :contentReference[oaicite:2]{index=2}:contentReference[oaicite:3]{index=3}

Key Highlights:

• Stoic Philosophy in Medicine: Dr. Santiago explores how Stoic principles—such as embracing discomfort, focusing on what can be controlled, and maintaining equanimity—can serve as valuable tools for medical professionals facing the challenges of residency and clinical practice.
• Running as a Metaphor: The article draws comparisons between the perseverance required in long-distance running and the resilience needed in the medical field, emphasizing the importance of mental fortitude and consistent effort.
• Personal Narratives: Through candid reflections, Dr. Santiago shares personal experiences of navigating the physical and emotional demands of medical training, highlighting the growth that emerges from confronting and embracing pain.

This piece offers a compelling perspective on the cultivation of resilience, suggesting that the challenges faced in both medicine and athletics can be opportunities for personal development when approached with a Stoic mindset.:contentReference[oaicite:12]{index=12}

Read the full article on the PRESENT Podiatry website.

Keywords:
Stoicism,
medical residency,
running,
resilience,
Dr. Santiago

Preventive Care for Individuals with Deep Pressure Ulcers in Sweden: A Mobile Team Approach

A recent study published in Health Science Reports details the implementation and outcomes of a mobile pressure ulcer (PU) team in Sweden, aimed at enhancing preventive care for individuals with deep pressure ulcers. :contentReference[oaicite:2]{index=2} This initiative represents a shift towards more proactive and patient-centered wound care management.:contentReference[oaicite:5]{index=5}

Key Highlights:

• Mobile PU Team Establishment: The Swedish healthcare system introduced a mobile PU team to deliver and monitor preventive interventions and advanced wound care treatments both at patients’ homes and outpatient clinics.
• Comprehensive Care Delivery: The team focused on individualized care plans, incorporating risk assessment, patient education, and tailored treatment strategies to address the specific needs of each patient.
• Improved Patient Outcomes: The mobile team’s approach led to enhanced healing rates, reduced incidence of new pressure ulcers, and increased patient satisfaction due to the convenience and personalized nature of the care provided.

This study underscores the effectiveness of mobile healthcare teams in managing complex wound care needs, particularly for patients with limited mobility or access to traditional healthcare facilities. By bringing specialized care directly to patients, the Swedish model demonstrates a promising strategy for improving outcomes in pressure ulcer prevention and treatment.:contentReference[oaicite:16]{index=16}

Read the full article on the Health Science Reports website.

Keywords:
pressure ulcers,
mobile healthcare teams,
wound care management,
preventive care,
Sweden healthcare

ACFAP 2025 Pediatric Foot & Ankle Seminar: Advancing Clinical Excellence

The American College of Foot & Ankle Pediatrics (ACFAP) is hosting its 2025 Pediatric Foot & Ankle Seminar from September 18–20, 2025, at the Holiday Inn in Estes Park, Colorado, adjacent to the scenic Rocky Mountain National Park. This Continuing Medical Education (CME) event will feature leading authorities on pediatric foot and ankle conditions, covering topics such as pediatric history and physical examination, flatfoot, equinus, sports medicine, surgery, and rotational conditions. :contentReference[oaicite:4]{index=4}:contentReference[oaicite:5]{index=5}

Key Highlights:

• Comprehensive Curriculum: Attendees will engage in sessions that delve into developing effective protocols for treating pediatric patients, evaluating surgical versus non-surgical options for common pediatric foot and ankle pathologies, and improving patient outcomes for conditions like flatfeet, juvenile hallux valgus (HAV), and equinus.
• Networking Opportunities: The seminar will commence with an outing to Rocky Mountain National Park on Thursday, September 18, providing a unique opportunity for attendees to connect with peers in a relaxed setting.
• Accreditation: This CME activity is designed to enhance the knowledge and skills of healthcare professionals specializing in pediatric foot and ankle care.

Registration Details:

• Non-Members: $674
• 2025 ACFAP Members: $424
• Residents: $275
• Students: $250

No commercial interest has provided financial support for this continuing education activity. :contentReference[oaicite:22]{index=22}:contentReference[oaicite:23]{index=23}

For more information and to register, visit the ACFAP Events page.

Keywords:
ACFAP,
pediatric foot and ankle,
continuing medical education,
flatfoot,
equinus,
juvenile hallux valgus

The Human Body Is Designed to Walk: Insights from Linda Rusiecki, DPT

In her article, “The Human Body Is Designed to Walk: It Thrives When It Walks”, Linda Rusiecki, DPT, Inpatient Rehabilitation Educator at Corewell Health, emphasizes the fundamental role of walking in human health and the importance of mobility aids in supporting this function. She underscores that walking is not only essential for physical well-being but also for psychological and emotional health.

Key Highlights:

• Evolutionary Perspective: Rusiecki discusses how the human body has evolved to walk upright, making walking a natural and necessary activity for maintaining health.
• Health Benefits: Regular walking contributes to improved cardiovascular health, enhanced mood, better balance, and increased independence, especially in older adults.
• Role of Mobility Aids: For individuals facing mobility challenges, appropriate aids such as walkers, canes, or prosthetics can facilitate walking, thereby promoting autonomy and quality of life.
• Rehabilitation Focus: In rehabilitation settings, encouraging walking with or without aids is a primary goal to restore function and prevent complications associated with immobility.

Rusiecki’s insights highlight the intrinsic link between walking and overall health, advocating for the use of mobility aids as tools to enhance movement and independence. Her perspective serves as a reminder of the importance of maintaining mobility throughout all stages of life.

Read the full article on the Medical Tech Outlook website.

Keywords:
walking,
mobility aids,
rehabilitation,
Linda Rusiecki,
Corewell Health

Overview of Diabetic Foot Ulcers: Causes, Diagnosis, and Management

This detailed summary, adapted from a comprehensive article on Medscape, outlines the essential aspects of diabetic foot ulcers (DFUs), including risk factors, clinical presentation, diagnostic workup, and treatment approaches. Diabetic foot ulcers are a major complication of diabetes and contribute significantly to patient morbidity and healthcare costs.

Key Highlights:

• Causes and Risk Factors: DFUs are commonly caused by peripheral neuropathy (loss of protective sensation), peripheral arterial disease (reduced blood flow), and structural foot deformities. These factors together increase the likelihood of ulcer formation and delay healing.
• Clinical Presentation: DFUs typically present as open sores, especially on weight-bearing areas of the foot. Redness, swelling, discharge, and odor may indicate infection. Notably, pain is often absent due to neuropathy.
• Diagnosis: Evaluation includes physical and neurological exams, vascular assessments (e.g., ABI), imaging (X-ray or MRI), and lab tests to detect infection or bone involvement.
• Treatment: Effective care involves offloading pressure, regular wound debridement, appropriate dressings, infection management, tight glycemic control, and in some cases, surgery or revascularization. Multidisciplinary care is often required.
• Prognosis: Up to 20% of DFUs may lead to lower-limb amputation. Recurrence is common, so prevention through foot care education and ongoing monitoring is critical.

With early detection and a coordinated treatment plan, many diabetic foot ulcers can be healed and serious complications avoided. Healthcare providers should remain vigilant for early signs in diabetic patients and implement evidence-based strategies to improve outcomes.

Read the full article on the Medscape website.

Keywords:
diabetic foot ulcers,
wound care,
debridement,
peripheral neuropathy,
offloading

Columbia VA Podiatrist Recognized for Research on Emotional Impact of Diabetic Amputations

Dr. Brandon Brooks, a podiatrist at the Columbia VA Health Care System, received first place honors at the 10th Annual Conference of the American Society of Podiatric Surgeons for his innovative research on the psychological burden of diabetes-related amputations. His study introduces the concept of DREADD—Diabetes-Related Extremity Amputation Depression & Distress—to better understand the emotional trauma experienced by patients undergoing even minor amputations.

Key Highlights:

• DREADD Framework: Dr. Brooks coined the acronym to emphasize that minor, non-traumatic amputations—such as toe removal—can lead to serious emotional consequences, including depression, anxiety, and treatment noncompliance.
• Impact on Patient Behavior: The study found that approximately 90% of patients reported increased emotional distress after minor amputations, which contributed to poorer disease management, such as missed appointments and medication lapses.
• Call for Integrated Care: Dr. Brooks advocates for integrating behavioral health into limb preservation teams and utilizing tools like the PHQ-9 to screen for depressive symptoms during podiatric care.

This research adds an important dimension to limb preservation, stressing that successful outcomes require attention not only to physical recovery but also to emotional well-being. Dr. Brooks collaborated on the study with his brother, Dr. Bradley Brooks, a board-certified psychiatrist, highlighting the value of interdisciplinary teamwork in advancing diabetic foot care.

Read the full article on the VA News website.

Keywords:
diabetes-related amputations,
psychological distress,
limb preservation,
Brandon Brooks,
Bradley Brooks

Upcoming Event: Paediatric Skin Health and Wound Healing Study Day

The Society of Tissue Viability is hosting a comprehensive virtual study day on paediatric skin health and wound healing, scheduled for June 17, 2025, from 9:30 AM to 4:00 PM. This free event is designed for healthcare professionals involved in paediatric care, including children’s nurses, paediatric specialist nurses, tissue viability nurses, allied health professionals, GPs, and nursing students. :contentReference[oaicite:3]{index=3}:contentReference[oaicite:4]{index=4}

Key Highlights:

• Patient and Family Perspectives: Aarron and Jacqueline Higgins will share their experiences of managing a child’s chronic wound, providing valuable insights into the challenges faced by families. :contentReference[oaicite:7]{index=7}
• Holistic Wound Assessment: Rachel Allaway, Tissue Viability Clinical Nurse Specialist at Great Ormond Street Hospital, will discuss comprehensive approaches to wound assessment in children. :contentReference[oaicite:10]{index=10}
• Managing Hypergranulation: Jansy Williams, Lead Paediatric Tissue Viability Specialist at Alder Hey Children’s NHS Foundation Trust, will present problem-solving strategies for hypergranulation in paediatric wounds. :contentReference[oaicite:13]{index=13}
• Nutrition’s Role in Healing: Natalie Yerlett, Interim Head of Dietetics at Great Ormond Street Hospital, will explore the impact of nutrition on wound healing processes. :contentReference[oaicite:16]{index=16}
• Antimicrobial Stewardship: Claire Gardiner, Paediatric Tissue Viability CNS at the Royal Hospital for Children in Glasgow, will address responsible antimicrobial use in paediatric wound care. :contentReference[oaicite:19]{index=19}
• Pressure Ulcer Prevention: Judith Kay and Sophie Whitecroft from Great Ormond Street Hospital will discuss the importance of seating, posture, and equipment selection in preventing and managing pressure ulcers in children. :contentReference[oaicite:22]{index=22}

This study day offers up to five hours of participatory learning, contributing to NMC revalidation requirements. Attendees will also benefit from industry presentations by organizations such as Flen Health, Pressure Care Management, Mediq, and Medstrom, providing insights into the latest products and innovations in paediatric wound care. :contentReference[oaicite:25]{index=25}:contentReference[oaicite:26]{index=26}

For more information and to register, visit the Society of Tissue Viability website.

Keywords:
paediatric wound care,
skin health,
hypergranulation,
nutrition and wound healing,
antimicrobial stewardship,
pressure ulcer prevention