Tag: MRSA

Micreos secures €32 million for its endolysin-based platform as sustainable alternative to antibiotics

THE HAGUE, The Netherlands, Sept. 30, 2021 /PRNewswire/ — Dutch biotechnology company Micreos announced it has secured another €32 million in funding to further develop its endolysin platform technology, based on targeted killing of only unwanted bacteria. This funding round will help Micreos accelerate its clinical development programs for atopic dermatitis, diabetic (MRSA) wounds and bloodstream infections, based on its pharmaceutical lead compounds, XZ.700 and SP.800.

Endolysins as precision anti-bacterials

In its search for solutions, Micreos’ researchers, in close collaboration with the Swiss Federal Technology Institute ETH Zurich, turned to nature’s own precision anti-bacterials, named endolysins. Unlike antibiotics, these highly specific enzymes have the ability to target only unwanted bacteria, while preserving the microbiome, comprising billions of ‘good’ bacteria, essential for our health. Endolysins are safe and environmentally friendly. Because of their working mechanism, development of resistance is not expected.

Addressing unmet medical needs

XZ.700 targets Staphylococcus aureus (S. aureus), including the antibiotic-resistant MRSA, while preserving Staphylococcus epidermidis, considered to be beneficial on the skin and conducive to wound healing. SP.800 targets all staphylococcal species … read more

Researchers explore promising treatment for MRSA ‘superbug’

A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.

Treating wounds with the secretion of a type of stem cell effectively reduced the viability of methicillin-resistant Staphylococcus aureus – better known as MRSA – according to a new study from researchers at the Baker Institute for Animal Health, part of the College of Veterinary Medicine (CVM). Moreover, the secretion stimulated the surrounding skin cells to build up a defense against the bacterial invader, the researchers found … read more

Antibacterial Effect and Promoting of Skin Wound Healing After Infected with Methicillin-Resistant Staphylococcus aureus for the Novel Polyvinyl Nanoparticles

Wounds represent a serious, and often overlooked, health problem in the global world. Importantly, if left untreated, several complications arise including infection, amputation, and long-term morbidity. The wound treatment has placed a massive financial burden on the health-care system, with serious and disturbing consequences for the affected patients. The development of new treatments that enhance the wound healing process and prevent, or limit, scarring is needed. Impaired wound healing is characterized by a loss of synchronization of the molecular interactions required for skin tissue repair.4 Six million patients a year are affected by wounds, costing the health-care system an estimated $25 billion dollars. Wound infection is the most common impediment to wound healing, leading to increase the morbidity and mortality among patients … read more

Sustainable fabric made from tree bark could cut MRSA infection rates

A traditional Ugandan cloth that uses tree bark to make sustainable textiles could be used to treat skin wounds after new research shows it has antimicrobial properties to fight against tough infections such as MRSA … MRSA—Methicillin-resistant Staphylococcus aureus—is an infection caused by bacteria that is resistant to many different antibiotics … continue