Cost-Effectiveness and Budget Impact of Topical Antimicrobial Polyhexamethylene Biguanide with a Surfactant


Cost-Effectiveness and Budget Impact of Topical Antimicrobial Polyhexamethylene Biguanide with a Surfactant (Betaine) on Wound Bed Preparation in Venous Leg Ulcers: An Analysis in Australia from a Community Perspective

Summary: This Australian study evaluated the cost-effectiveness and budget impact of using polyhexamethylene biguanide (PHMB) combined with a surfactant (betaine) for wound bed preparation in venous leg ulcers. From a community healthcare perspective, the intervention was found to be cost-effective, improving healing rates while reducing overall treatment costs through faster wound bed preparation and fewer complications.

Key Highlights:

  • PHMB + betaine improves wound bed preparation in VLUs
  • Cost-effective with positive budget impact in community settings
  • Reduces healing time and resource utilisation
  • Supports broader adoption in Australian wound care pathways

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Keywords: PHMB betaine, venous leg ulcer cost, wound bed preparation