Use of Hypothermically Stored Amniotic Membrane on Diabetic Foot Ulcers



Use of Hypothermically Stored Amniotic Membrane on Diabetic Foot Ulcers: A Multicentre Retrospective Case Series

Summary: This multicentre retrospective study assessed hypothermically stored amniotic membrane (HSAM) in real-world treatment of diabetic foot ulcers. The advanced tissue product supported consistent healing across multiple centres, demonstrating good integration, reduced healing time, and low complication rates. Results reinforce HSAM as a reliable option for hard-to-heal DFUs.

Key Highlights:

  • Strong healing outcomes in a multicentre real-world setting
  • Effective for chronic, non-healing DFUs
  • Favourable safety and integration profile
  • Practical adjunct for advanced wound care teams

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Keywords: hypothermically stored amniotic membrane, HSAM DFU, amniotic membrane wound