Efficacy and safety of polyhexanide compared with other wound dressings in patients with various wound types: a systematic review and meta-analysis
Summary: This systematic review and meta-analysis evaluates polyhexanide-containing dressings against alternative options across multiple wound types, synthesizing data on healing, infection control, and adverse events to guide formulary and bedside choices.
Key Highlights:
- Compares clinical endpoints: time-to-closure, infection indicators, pain, odor, and quality of life.
- Assesses safety profile and tolerance across etiologies (e.g., VLUs, DFUs, pressure injuries).
- Discusses antimicrobial stewardship considerations for antiseptic dressings.
- Notes heterogeneity in study designs and recommends standardized outcome reporting.
Keywords:
polyhexanide,
systematic review,
meta-analysis,
antiseptic dressings