Expediting Acute Wound Healing by Integrating Multiple Therapeutic Strategies

Expediting Acute Wound Healing by Integrating Multiple Therapeutic Strategies: A Case Series

Summary: This case series describes how combining multiple advanced wound therapies early in acute wounds can accelerate healing. The authors analyzed 124 patients treated with a multimodal regimen and found a median healing time of 19 days, with lower utilization of healthcare resources compared to traditional approaches.

Key Highlights:

  • Early specialist consultation (median 2 days) was part of the protocol and may contribute to improved outcomes.
  • Therapeutic combinations included hypochlorous acid cleansing, negative pressure wound therapy (NPWT) with instillation, collagen/oxidized regenerated cellulose, silver, manuka honey, and foam dressings.
  • Median healing time across 124 patients was 19 days; notable delays were linked to smoking, immunocompromise, and lack of access to wound supplies.
  • Multimodal treatment reduced the number of dressing changes, follow-up visits, and home care needs compared to historical standards.
  • Compliance with the T.I.M.E. + S (tissue, inflammation/infection, moisture balance, edge/periwound, size/social) assessment framework guided interventions dynamically throughout care.

Read the full case series on HMP Global Learning Network

Keywords:
Kathy E. Gallagher,
Emily C. Alberto,
John Getchell,
Jessie Powell,
Luis Cardenas,
acute wounds,
multimodal therapy,
NPWT instillation,
wound healing acceleration