Negative-Pressure Therapy No Better for Open Fractures

Negative-pressure therapy does not improve 12 month outcomes compared with standard wound dressings in adults with severe open fractures of the lower limb, according to a study published online June 12 in JAMA.


The study is the largest randomized controlled trial (RCT) to compare negative-pressure therapy to standard wound care in this setting.


“The findings do not support this treatment for severe open fractures,” write Matthew Costa, PhD, from the University of Warwick, Coventry, United Kingdom, and colleagues with the UK Wound management of Open Lower Limb Fractures (WOLLF) Collaboration … read more