Clinical Outcomes and Safety of Stem Cell Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis
Summary: This systematic review and meta-analysis assesses the clinical outcomes and safety profile of stem cell therapy (including mesenchymal stem cells, bone marrow-derived cells, and others) as an adjunctive treatment for diabetic foot ulcers. Results indicate improved wound healing rates, increased complete closure, and enhanced angiogenesis with a generally favorable safety profile.
Key Highlights:
- Significant improvement in complete wound closure rates
- Enhanced angiogenesis and tissue regeneration
- Acceptable safety profile across multiple stem cell types
- Promising adjunctive therapy for hard-to-heal DFUs
Keywords: stem cell therapy DFU, mesenchymal stem cells wound, regenerative therapy diabetic foot