Psychological Stress Impairs Wound Healing and Collagen Production, New Review Confirms
Summary: This comprehensive review synthesises evidence showing that psychological stress negatively affects all phases of wound healing. Mechanisms include elevated cortisol, altered immune responses, reduced angiogenesis, and impaired collagen synthesis. The authors highlight the need for integrated stress-management strategies as part of holistic wound care to improve healing outcomes.
Key Highlights:
- Stress impairs inflammation resolution and delays healing
- Significant reduction in collagen deposition documented
- Multiple neuroendocrine and immune pathways involved
- Supports routine incorporation of stress reduction in wound care plans
Keywords: psychological stress wound healing, stress collagen production