Development of a banana stem fiber-reinforced chitosan–xanthan gum wound healing patch loaded with Tridax procumbens extract for biomedical applications
Summary: January 27, 2026 study develops bio-composite wound patch via interpenetrating polymeric network (IPN) of banana pseudo-stem fiber-reinforced chitosan-xanthan gum hydrogel loaded with Tridax procumbens extract (traditional healer). Addresses single-polymer limits (weakness, poor absorption/drug loading) through synergy. Characterized: SEM (rough morphology, uniform fiber dispersion), XRD (78.43% crystallinity), FTIR (bioactive integration). Biologically: 60% antioxidant (IC50 ~7.67 µg/ml), 78% L929 fibroblast scratch closure in 24h at 25 µg/ml extract, 75% viability at 5 µg/ml (MTT). Positions as eco-friendly, bioactive dressing for protection, exudate management, healing promotion in biomedical applications.
Key Highlights:
- Properties: Rough surface, high crystallinity, antioxidant/bioactive.
- In vitro: Strong closure/viability in fibroblasts.
- Implications: Natural/sustainable alternative for chronic wounds.
- Relevance: Aligns with plant-derived/synthetic hybrid innovations.
Keywords: banana stem fiber, chitosan xanthan, Tridax procumbens, bio-composite patch