Mechanosensor Plays Critical Key Role in Skin Wound Healing

PIEZO1, an ion channel mechanosensor found within cells, has been revealed to play a key role in regulating the speed of skin wound healing by researchers at the University of California, Irvine (UCI).

Published today in eLife, the study (“Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing”) found that in mice lacking the ion channel protein PIEZO1 in keratinocytes, skin wounds heal faster than in mice with increased PIEZO1 function in keratinocytes … read more

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