Diabetic foot ulcers are a major health and economic global burden, but ultimately, at least in theory, they’re preventable. The re-ulceration rate is as high as 65% within 5 years, and among persons who initially present with a diabetic foot ulcer, up to 25% may require amputation … One of the most important risk factors for diabetic foot ulceration is diabetic peripheral neuropathy. This involves loss of sensory perception, haptic feedback, and pain perception, so patients can’t self-regulate their foot pressures. It’s thought that these high foot pressures over time cumulatively contribute to the development of diabetic foot ulcers … read more