Electrochemical Modulation of Host-Microbe Dynamics in Wound Healing
Summary: This review examines the growing field of bioelectric and electrochemical therapies in wound care. Electrical fields and electrochemical modulation can directly influence bacterial behavior, disrupt biofilms, promote beneficial microbial communities, and enhance host immune responses. The authors discuss current devices, mechanisms of action, and potential applications for chronic wounds, including diabetic foot ulcers. This approach represents a promising adjunct to traditional wound care by targeting the complex host-microbe interface.
Key Highlights:
- Electrical stimulation affects both host cells and wound pathogens
- Potential to reduce biofilms and pathogenic load
- Supports angiogenesis and tissue regeneration
- Emerging as a complementary strategy in advanced wound management
Keywords: electrochemical wound healing, bioelectric therapy, wound microbiome