Electrochemical Modulation of Host-Microbe Dynamics in Wound Healing
Summary: This comprehensive review examines the emerging field of bioelectric and electrochemical therapies in wound care. Electrical stimulation and electrochemical modulation can influence host-microbe interactions, reduce pathogenic biofilms, promote beneficial microbial communities, and enhance tissue repair. The authors discuss mechanisms, current devices, and future directions for translating these technologies into practical wound care strategies for chronic ulcers, including diabetic foot ulcers.
Key Highlights:
- Electrical fields can directly affect bacterial behavior and host immune response
- Potential to disrupt biofilms and promote healing in stalled chronic wounds
- Bridges microbiology, bioengineering, and clinical wound care
- Promising adjunct for difficult-to-treat infections and non-healing ulcers
Keywords: electrochemical wound healing, bioelectric wound care, wound microbiome