Precision-Based Approach to Bioactive Skin Allograft Application in Nonhealing Wounds
Summary: This case series from the *Wounds* program describes a precision-targeted strategy for using bioactive skin allografts in nonhealing wounds. By applying grafts based on individualized assessments of wound biology and patient risk factors, clinicians report improved integration, reduced failures, and better overall healing potential.
Key Highlights:
- Tailored grafting: Allografts were applied selectively based on wound biomarkers, clinical progression, and assessment of “healing potential.”
- Clinical outcomes: Several cases showed enhanced graft take, reduced exudate, and progressive closure where standard care alone had stalled.
- Failure reduction: The precision approach helped avoid graft failure in unfavorable wound beds by delaying or altering timing and adjunctive measures.
- Practical guidance: The authors offer a decision-tree algorithm to guide clinicians on when and how to apply bioactive grafts for best effect.
Read the full case series on HMP Global Learning Network
Keywords:
bioactive skin allograft,
precision-based approach,
nonhealing wounds,
graft integration,
healing potential assessment