Primary Cutaneous Aspergillosis Due to Aspergillus flavus in an Immunocompetent Patient
Summary: Case report of 56-year-old immunocompetent male with chronic facial/right ankle ulcers (2 years) due to primary cutaneous aspergillosis from Aspergillus flavus. Lesions started pruritic, worsened by herbal compresses; diagnosed via culture (green colonies), staining, mNGS. Treated with IV/oral voriconazole + surgical debridement/wound care; healed after 46 days. Rare in immunocompetent; highlights risks in chronic wounds/trauma with contamination (e.g., diabetes/vulnerable populations prone to progression).
Key Highlights:
- Presentation: Pruritic erythema → ulcers with crust/pus; herbal aggravation.
- Diagnosis: A. flavus confirmed; no bacterial co-infection.
- Treatment/Outcome: Antifungal + debridement → gradual healing.
- Relevance: Fungal risks in persistent wounds; early intervention key to avoid systemic spread.
Keywords: cutaneous aspergillosis, Aspergillus flavus, chronic ulcer infection, voriconazole