Observational Study of Venous Leg Ulcer Treated With Native Collagen-Alginate Dressing and Impact on Wound-Related Quality of Life
Summary: Observational study (n=60 non-healing VLUs, 1.5-24 months) used native collagen-alginate (Cutimed Epiona) + SOC/compression. At 4 weeks: area ↓32% (17.8 to 11.4 cm², p<0.0001); 4 complete closures; pain ↓56% (VAS 3.9 to 1.7, p<0.0001); analgesic use ↓47%; QoL improved (Wound-QoL total/sub-scores p<0.0001). Periwound skin/exudate improved; rated 'very good/good' by all HCPs. Safe adjunct accelerating healing/QoL in VLUs.
Key Highlights:
- Area: ↓32% mean; 4 full closures.
- Pain: VAS ↓56%; analgesics ↓ from 61% to 33%.
- QoL: Significant ↓ Wound-QoL scores (body/wellbeing/everyday).
- Safety: 8 moderate AEs (unlikely related).
Keywords: collagen alginate, VLU, healing, QoL, observational