Incidence, Hospitalization and Mortality and Their Changes Over Time in People with a First Ever Diabetic Foot Ulcer
Summary: Analysis of UK CPRD GOLD database (2007-2017, n=129,624 diabetes patients) shows declining trends in first DFU outcomes for type 2 diabetes: incidence rate ratio per year 0.97, hospitalization OR 0.89, 1-year mortality OR 0.94. No significant changes for type 1. Mean first DFU incidence 2.5/1000 person-years (type 2) vs 1.6 (type 1). Improvements attributed to better primary care prevention/management of initial ulcers.
Key Highlights:
- Incidence: Type 2 ↓ (IRR 0.97/year); type 1 stable.
- Hospitalization: Type 2 average 8.2% ↓ (OR 0.89).
- Mortality: Type 2 11.7% 1-year risk ↓ (OR 0.94).
- Population: UK primary care; insulin/non-insulin prescriptions.
- Implications: Positive shift in type 2 DFU prevention/outcomes.
Keywords: DFU incidence, UK trends, hospitalization, mortality, primary care