DAE Launches India’s First Nitric-Oxide Wound Dressing for Diabetic Foot Ulcers



DAE Launches India’s First Nitric-Oxide Wound Dressing for Diabetic Foot Ulcers

Summary: The Department of Atomic Energy (DAE) launched ColoNoX, India’s first nitric-oxide (NO)-releasing wound dressing for diabetic foot ulcers (DFUs), developed by Bhabha Atomic Research Centre (BARC) and validated in Phase II/III trials. The DCGI-approved product enhances angiogenesis and antimicrobial action, accelerating healing in 70% of cases and reducing amputation risks by 40% in resource-limited settings. Affordable and locally produced, it addresses India’s 77M diabetics, with rollout via public-private partnerships for nationwide access.

Key Highlights:

  • ColoNoX: NO from chitosan matrix promotes vascularization and kills bacteria without resistance.
  • Trials: Phase II/III show 70% faster granulation; 40% amputation reduction vs standard dressings.
  • Impact: Targets 15% DFU incidence; cost-effective for rural care.
  • Launch: DAE/BARC initiative; partnerships for distribution.
  • Quote: DAE Secretary: “Breakthrough for diabetic complications in India.”

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Keywords: nitric oxide dressing, diabetic foot ulcers, ColoNoX, BARC, amputation reduction