Impact of Using Zinc Oxide Versus Moist Exposed Wound Ointment (MEBO) in Treatment of Second Stage Pressure Ulcer

Impact of Using Zinc Oxide Versus Moist Exposed Wound Ointment (MEBO) in Treatment of Second Stage Pressure Ulcer

Summary: This randomized controlled trial is comparing the effectiveness of zinc oxide with Moist Exposed Wound Ointment (MEBO) for treating stage II pressure ulcers. Conducted at King Abdullah Medical City in Saudi Arabia, the study aims to determine whether zinc oxide accelerates wound healing compared to MEBO. Participants receive either zinc oxide or MEBO applied twice daily, and progress is measured using the Bates-Jensen Wound Assessment Tool (BWAT) for up to 30 days.

Key Highlights:

  • Design: Open-label, randomized controlled trial.
  • Participants: Adults with newly diagnosed stage II pressure ulcers.
  • Interventions: Zinc oxide ointment vs MEBO ointment, both applied every 12 hours.
  • Primary outcome: Healing progress measured daily using BWAT scores for up to 30 days.
  • Secondary outcome: Time to complete ulcer recovery (days).
  • Status: Currently recruiting.
  • Sample size: 76 participants planned.

View the full trial details on ClinicalTrials.gov

Keywords:
zinc oxide,
MEBO ointment,
pressure ulcer stage II,
BWAT,
Ebtisam Abdellatif Ebrahim