Time in Range as a Predictor of Diabetic Foot Ulcer Healing

Time in Range as a Predictor of Diabetic Foot Ulcer Healing

A prospective study reported on June 16, 2025, in DiabeticFootOnline.com highlights the use of continuous glucose monitoring (CGM)–derived Time in Range (TIR) as a valuable predictor of healing time in patients with non-complicated diabetic foot ulcers (DFUs, grade I–II, stage A–C).

Key Highlights:

  • Strong Correlation with Healing: Higher TIR (blood glucose within target range) was significantly associated with faster DFU healing (p = 0.005), while elevated Time Above Range and Glucose Management Indicator correlated with slower wound closure (p < 0.05). :contentReference[oaicite:1]{index=1}
  • Real-world Application: Patients wore CGM devices from baseline until complete wound closure under standard outpatient care, demonstrating TIR’s practical value in routine clinical settings. :contentReference[oaicite:2]{index=2}
  • Glycemic Control Matters: Findings support the concept that maintaining optimal glycemic stability via CGM can directly influence wound healing outcomes in DFUs. :contentReference[oaicite:3]{index=3}

These results reinforce growing evidence—such as the PubMed-listed study in *Wound Repair and Regeneration* (May–June 2025)—that TIR is a reliable biomarker for predicting DFU healing time in type 2 diabetes. :contentReference[oaicite:4]{index=4}

Read the full article on DiabeticFootOnline.com.

Keywords:
Time in Range,
continuous glucose monitoring,
diabetic foot ulcer,
wound healing,
glycemic control