Biofabrication of ZnO/Malachite nanocomposite and its coating with chitosan to heal infectious wounds

Zahra Rajabloo, Mohammad Reza Farahpour, Parvaneh Saffarian & Saeed Jafarirad

 

Skin wounds cause damage to healthcare systems and loss economic. Wounds are classified as acute and chronic based on the pathogenesis and consequences. Acute wounds induce molecular processes to obtain structural integrity. Immune cells and factors play pivotal roles in acute wound healing3. The faulted regulation of the immune response results in the formation of chronic wounds. Infectious wounds are a form of acute wounds characterized by the presence of bacteria in viable tissue and damage to tissues. The infections start with bacteria colonization and can cause systemic infection. Staphylococcus aureus and Pseudomonas aeruginosa are the most common bacteria in infected wounds. In infected wounds, the wound healing process is delayed. Infected wounds also cause overproduction of reactive oxygen species and induce faults in antioxidant systems … read more