Chlorhexidine Delays Wound Healing in Human Skin

Angela Gibson, MD, PhD, FACS, Aiping Liu, PhD, Collin L Tran, BS, Sameeha E Hassan, BS

 

Chlorhexidine (CHG) is ubiquitous in surgical perioperative care. In vivo studies of CHG cytotoxicity on human skin are lacking. Given the use of CHG for daily wound cares and as a presurgical scrub, including donor site preparation, we sought to identify if CHG cytotoxicity would persist in a clinically relevant in vivo human skin xenograft model … read more