Category: Articles

Seattle Lower Extremity Surgical Symposium (SLESS)

March 16-19, 2022
Cedarbrook Lodge
St. Anne’s Hospital
Up to 18 CECH– Lectures (3/17-18)
Up to 8 CECH—Labs (3/19)
The 5th Annual Seattle Lower Extremity Surgery Symposium—SLESS offers continuing medical education on surgical techniques for lower extremity trauma and reconstruction. SLESS is a 3-day course, featuring two days of didactic lectures held at the Cedarbrook Lodge, 5 minutes from Seatac airport and one day of cadaveric skills sessions held at nearby St Anne’s Hospital 5 minutes’ drive from the hotel . Learn from a faculty of leading (MD and DPM) lower extremity surgeons … read more


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A new district nursing model improves venous leg ulcer healing rates

The predominant aetiology of lower leg ulcers (VLU) are caused by venous insufficiency. In 2016 a new district nursing model was introduced using nurses specialising in leg ulcer assessment and management. The specialist nurses provided district nurse education on leg ulcers and conducted vascular assessments to identify venous ulcer aetiology, enabling early compression therapy to increase healing rates and prevent wound chronicity … read more
This article requires membership of Wounds Australia


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Pressure area care module

Education for pressure ulcer assessment and prevention is essential to ensure that patients receive safe, effective, harm-free care. Aligning an effective care bundle with the best possible evidence-based practice helps to safeguard patients by reducing the risk of this classic avoidable harm.
Pressure area care … read more


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Socioeconomic deprivation tied to amputation risk in people with diabetic foot ulcers

People with diabetic foot ulcers (DFUs) who live in areas with a high level of deprivation may be more likely to require major amputation than those living in less deprived areas, suggest findings from a French cohort study … Jean-Baptiste Bonnet (Hôpital Lapeyronie, Montpellier) used the French National Health Data System to evaluate amputation data from 15,507 individuals in the Languedoc-Roussillon administrative area with any type of diabetes who experienced a first DFU between 2015 and 2017. These people were aged an average of 70 years, 55% were men, and 20% required hospitalization … read more

When and how to culture a chronic wound

Chronic wound infections are a significant healthcare burden, contributing to increased morbidity and mortality, prolonged hospitalization, limb loss, and higher medical costs. What’s more, they pose a potential sepsis risk for patients. For wound care providers, the goal is to eliminate the infection before these consequences arise … Most chronic wounds are colonized by polymicrobial aerobic-anaerobic microflora. However, practitioners continue to debate whether wound cultures are relevant. Typically, chronic wounds aren’t cultured unless the patient has signs and symptoms of infection, which vary depending on whether the wound is acute or chronic … read more

Is Your Wound Bioburdened? Case 3

A 77-year-old, non-smoking female with diabetes came into the clinic for a postoperative assessment … The patient presented with a non-healing surgical wound resulting from a great toe amputation 3 weeks prior … She had poor vascularity, normal blood sugar levels, and there were no signs or symptoms of infection (no malodor, purulent drainage, or cellulitis) … read more

PRESENT 5-Minute Podiatry Clinical Challenge – Drug-Induced Neuropathy

This week’s 5MinClinChallenge contributed by Robert G Smith, DPM, MSc, RPh, CPRS, focuses on a drug-induced neuropathy. This is an entity that you will see rarely, but when you do, you’ll want to be ready. See if you agree with Dr Smith’s approach … An 84-year-old female who resides in a temporary shelter presents with a complaint of new onset paresthesia in a stocking-glove distribution. She states that the numbness developed over the last month … read more

Hematoma of the Lower Extremity: Operative Interventions in the Wound Clinic Setting

Hematoma in the soft tissue, a swelling in the tissue caused by bleeding, is not an uncommon occurrence following trauma or operative procedures. Hematomas of the extremities can be seen in as many as 33 per 10 000 individuals annually. Most hematomas are considered to be minor problems following the initial injury; however, accumulation of blood in the tissues can result in necrosis of the overlying skin due to increased tissue pressure which occludes the subdermal and dermal capillaries. Even in the absence of increased tissue pressure, multiple cellular and biochemical changes that can result in tissue ischemia and necrosis have been identified. Platelets and white blood cells in the wound can release inflammatory cytokines, proteolytic enzymes, and toxic reactive oxygen species causing significant tissue damage … read more

N-Acetyl-Cysteine Increases Activity of Peanut-Shaped Gold Nanoparticles Against Biofilms

Formed by Clinical Strains of Pseudomonas aeruginosa Isolated from Sputum of Cystic Fibrosis Patients
Despite the clinical introduction of a spectrum of therapeutics with anti-bacterial and/or anti-inflammatory activities along with agents facilitating clearance of airways from thick and dehydrated sputum, the mortality rate of patients suffering from cystic fibrosis (CF) is still alarmingly high.1 Chronic inflammation and persistent Pseudomonas aeruginosa colonization are recognized as the major causes of lung tissue damage, lung transplantation, and mortality in CF subjects.2 Regardless of the intravenous or inhaled antibiotic therapies, the efficient treatment of pulmonary infections is considerably hampered mostly by the intrinsic or acquired resistance of P. aeruginosa to a variety of antibiotics,3 which is reinforced by its ability to produce drug-resistant biofilms. The latter is defined as three-dimensional communities of bacteria enclosed and protected by a self-produced extracellular polymeric substance (EPS) matrix, composed of polysaccharides (alginate), lysed cell debris proteins, lipids, extracellular DNA (eDNA), and bacteria-specific factors.4 Importantly, bacteria growth within biofilm in CF lungs is associated with their adaptation to antibiotics used frequently in the therapy of reoccurring pneumonia in CF patients. In this condition, an increased number of mutations associated with antibiotic resistance is generated. Such decreased susceptibility to the applied treatment followed by a lower metabolic rate of biofilm-embedded bacteria and their persistence makes the eradication of biofilms a challenging task.4 An approach to treat lung infections in patients with CF has evolved beyond antibiotic therapy, with the implementation of various airway clearance techniques (ACTs), in particular mucus thinners, to eliminate excess sputum … read more

Apps You and Your Patients With Diabetes Should Know

The trend toward real-time digitization of primary disease management continues to increase. Major reasons for this trend are that digitization can enable increased awareness of current patient health status, adherence to a treatment plan, and closer patient follow-up. Nowhere has this trend been more embraced than in the management of diabetes. Mobile applications (apps) have evolved to play a meaningful role in chronic disease management. Moreover, as diabetes-focused foot care is essential to helping people with diabetes avoid common and preventable complications such as wounds and lower extremity amputations (LEAs), a growing number of foot health-specific apps can aid in the management of this population … read more

Larva therapy makes a comeback

David Armstrong faced a predicament. He had a patient with an open wound that he needed to clean to remove dead tissue that could prevent proper healing, or worse. Infection could lead to severe pain and require limb amputation. But he didn’t have access to an operating room. Left with few other choices, he turned to an unexpected surgical assistant: maggots … While this scene might seem like one that unfolded on the front lines of the US Civil War or in a remote field hospital, Armstrong is actually a present-day surgeon at the University of Southern California. He is one of many clinicians turning to medical maggots as a tool for treating challenging wounds … read more

Odour management for chronic wounds – video

Sylvie Hampton describes the impact a malodorous wound may have on a patient’s quality of life and the mode of action of an activated charcoal dressing, which can be used as part of symptom management … watch

Could Custom Footwear Improve Adherence In An Ulcer Remission Program?

The authors took a closer look at adherence to footwear usage when patients with diabetes at high-risk for ulceration had custom-made shoes.1 Researchers assessed the percentage of overall steps during which subjects wore their custom-made shoes indoors and outdoors at baseline, 1-, and 12-months post-shoe dispensing. They created two cohorts based on indoor baseline adherence to shoe gear, less than 80% (primary group, n = 23) and greater or equal to 80% (secondary group n = 8). The authors also looked at peak plantar pressures of custom vs. non-custom indoor footwear, patient-related usability of the custom shoes, and ulcer recurrence at 12 months … read more

Exufiber® and Exufiber® Ag+: A review of the scientific and clinical evidence

Wound dressings have been created to manage a number of clinical conditions, including cavity wounds and wounds where exudate levels may vary from low levels in a relatively dry wound to highly exuding wounds where there is a genuine risk of damage to the surrounding skin. The evidence included in this supplement highlights some of the key pre-clinical and clinical studies conducted to evaluate the performance of Exufiber and Exufiber Ag+ gelling fibre dressings … read more

Diabetic foot ulceration Module

It is estimated that one in four people with diabetes will have a diabetic foot ulcer during their lives, as a result of a combination of diabetes-related complications. Development of infection in a diabetic foot ulcer may be limb- or life-threatening. However, with good diabetes management and regular assessment this can be prevented … read more

Can probiotics improve healing of diabetic foot ulcers? Results from a randomized controlled trial

Patients with a diabetic foot ulcer who received probiotic supplementation for 12 weeks experienced faster wound healing coupled with an improved glycemic and lipid profile compared with patients assigned placebo, according to findings from a randomized controlled trial … Sima Mohseni, of the infectious diseases and tropical medicine research center at Babol University of Medical Sciences in Iran, and colleagues analyzed data from 60 adults aged 40 years to 85 years with grade 3 diabetic foot ulcer, who randomly received either probiotic supplementation (n = 30) or placebo (n = 30) daily for 12 weeks between March and June 2016. Probiotic capsules contained lactobacillus acidophilus, lactobacillus casei, lactobacillus fermentum and Bifidobacterium bifidum. All participants also underwent standard treatment for wound care. Participants provided blood samples at baseline and 12 weeks and 3-day dietary records at baseline. Wound healing and glucose parameters served as the primary outcome … read more

Reconstructing the Holey Temple: A Composite Approach

Surgical defects involving multiple facial cosmetic subunits can be challenging to reconstruct. We report on a patient with a complex temporal defect following Mohs micrographic surgery (MMS) for a basal cell carcinoma (BCC). The extension of the defect across the left temple, cheek, and forehead hindered the utilization of linear closures or flaps. Healing by secondary intention was considered but was determined to be a suboptimal approach given the involvement of the convex cheek. A modified full-thickness skin graft (FTSG) with linear closures of the distal poles of the wound was ultimately utilized, with excellent cosmetic results at three-month follow-up. Herein, the authors summarize this case and the indications for FTSG and secondary intention healing (SIH) for surgical defects involving the face… read more

Treating Burns with Hypnosis

Patients can learn how to better react to acute and chronic pain.
Burn injuries lead to 1200 people (including 300 children) seeking emergency care every day in the United States. Burns cause physical pain, short and long-term psychological distress, and can also lead to long-term physical impairment because of scarring … The pain associated with burns can be caused by the injury, but sometimes there is even greater pain caused by the repeated cleansing and dressing of the wound … The circumstances that lead to the development of burns and related to wound care are sometimes so overwhelming that they lead patients to develop major mental illness including anxiety disorder … read more

The analysis for time of referral to a medical center among patients with diabetic foot infection

Diabetic foot infection (DFI) is a limb- and life-threatening complication for diabetic patients needing immediate and comprehensive treatment. Early referral of DFI patients to a diabetic foot center is recommended but there appears limited validated evidence, with the association between referral time and clinical outcomes of limb- preservation or in-hospital mortality still lacking … This retrospective research studied consecutive type 2 diabetic patients with DFI treated at the major diabetic foot center in Taiwan from 2014 to 2017. Six hundred and sixty-eight patients presented with limb-threatening DFI. After stratifying their referral days into quartiles, the demographic information and clinical outcomes were analyzed … read more

American Limb Preservation Society (ALPS) Names New CEO Georgia Krehbiel

The American Limb Preservation Society (ALPS) board of directors has named Georgia Krehbiel its new CEO. With more than 25 years of experience in both national and international organizations, Krehbiel has a proven track record of leading strategic initiatives to drive revenue and expand programs and services for those in need … “We are thrilled to welcome Georgia as the founding CEO,” noted David G. Armstrong, a Professor of Surgery at the Keck School of Medicine of the University of Southern California (USC) and the founding President of ALPS. “She has that rare combination of strategic vision, drive and innate humanity that is going to benefit not only ALPS, but the clinicians and patients we serve.” … read more

TELA Bio Announces U.S. Commercial Launch of SiteGuard™ No Rinse Antimicrobial Solution

Company expands product portfolio with focus on addressing surgical site infections in plastic reconstructive surgery

 

MALVERN, Pa., March 03, 2022 (GLOBE NEWSWIRE) — TELA Bio, Inc. (NASDAQ: TELA), a commercial-stage medical technology company focused on providing innovative soft-tissue reconstruction solutions that optimize clinical outcomes by prioritizing the preservation and restoration of the patient’s own anatomy, today announced the commercial launch of its SiteGuard No Rinse Antimicrobial Solution for use in plastic reconstructive surgery.
 
SiteGuard utilizes Next Science’s proprietary XBIO® Technology that supports surgical site and post-operative infection control by addressing the biofilms that make bacteria more resistant to traditional antimicrobial agents, disinfectants, and host immune defenses. XBIO Technology deconstructs biofilm, destroys the bacteria enveloped in the solution, and defends against bacterial recolonization. There is no known bacterial resistance to XBIO Technology, and the no-rinse delivery allows the solution to provide over five hours of ongoing protection against bacterial biofilms with exceptional rates of pathogen removal.
 
“SiteGuard is a complementary technology that we believe enhances our mission to deliver a portfolio of next-generation soft-tissue solutions that are both clinically effective and economically impactful,” said Antony Koblish, President and CEO of TELA Bio. “Early test market experience with SiteGuard has been encouraging, and we look forward to broadening awareness and usage of the technology nationwide.” … read more

Frailty Is a Risk Factor for Poor Diabetic Foot Ulcer Healing and Re-hospitalisation

The prevalence of frailty was higher in patients hospitalised with diabetic foot ulcers (DFUs) and was associated with poor wound healing and re-hospitalisation events … A better understanding of frailty may help guide individualised care planning for patients with DFUs … A prospective cohort study included 76 patients with DFUs (type 1 diabetes, n = 8; type 2 diabetes, n = 68) admitted to St Thomas’ Hospital, London … read more

Is Comedy a Prerequisite to a Successful Medical Career?

Milton Packer explores the innumerable reasons why laughter is essential to medicine
Like everyone else, I have been reading the distressing headlines about the Ukraine. The most important figure in the current conflict may be Vladimir Putin. But the most fascinating person is Volodymyr Zelenskyy (anglicized Zelensky) … A long-standing advocate of Ukrainian-Russia harmony, Zelenskyy was elected in a landslide as the President of the Ukraine in 2019. Although he initially underestimated the extent of Putin’s ambitions, Zelenskyy has become the central symbol for the Ukrainian resistance. Most people expected Zelenskyy would abdicate, fleeing the country to save his own life … read more

BOVINE DERMAL SCAFFOLDS – JWC Masterclass

Diabetic foot ulcers can be extremely challenging to treat and are associated with a high
morbidity and mortality … A recent large randomised controlled trial (RCT), found that a single application of a fetal bovine acellular dermal matrix in combination with standard of care (SOC) is a faster and more effective treatment for these ulcers than SOC alone* … In this masterclass, the RCT investigators will discuss the evidence, and explore the implications for practice with other clinicians who have used the dermal scaffold. The debate will focus on how to optimise the use of this technology on this wound type … read more

Swift Medical Launches the World’s First All-in-One Hyperspectral Imaging Device

to Make Healthcare More Accessible
Swift Medical, the global leader in digital wound care technology, unveiled the Swift Ray 1, a groundbreaking hardware device that wirelessly attaches to a smartphone camera and captures comprehensive clinical data to better support assessment, treatment and monitoring of skin and wound conditions. The Swift Ray 1 fits in the palm of a clinician or patient’s hand, making powerful medical imaging accessible anywhere, from the hospital to the home. Further, this advanced imaging enables the capture of accurate clinical data for every patient, regardless of skin tone, making wound care more equitable for everyone … “The future of wound care goes beyond what the naked eye can perceive and beyond the walls of the clinic, which is why our dream has always been to equalize and improve healthcare access for humanity through intelligent diagnostics,” said Carlo Perez, co-founder and CEO of Swift Medical. “The Swift Ray 1 gets us one step closer by helping clinicians and patients see below the surface of the skin, to heal wounds faster or prevent them from ever even developing.” … read more
Swift Medical Website

Obesity crisis is fuelling a rise in amputations linked to diabetes and gangrene

So many people with type 2 diabetes are losing limbs that it is now seen as normal – and we desperately need to take action

During the years I practised as a hospital doctor I saw only one amputee. He’d had his lower leg amputated for bad circulation worsened by smoking . He wouldn’t give up his Woodbines, though, not even if his other leg was in jeopardy … It’s a totally different picture today. Amputation is becoming commonplace – as a complication of diabetes. And no one seems worried … That’s because so many people are obese and it’s accepted as normal. Fat people develop Type 2 diabetes, and that, in turn, has become ‘normal’ … read more

A Comparison of the Biomechanical Performance of 3 Negative Pressure Wound Therapy Foams

Negative pressure wound therapy (NPWT) is a popular treatment option for a variety of chronic wounds, surgical incisions, and related conditions such as enterocutaneous or enteroatmospheric fistulae.1–8 The primary principle underlying NPWT, application of suction to a wound to promote healing, traces its roots to antiquity.1 The technology has evolved beyond the use of dedicated people who would use their mouths to suck on open skin wounds to the use of bell jars and hand pumps, which would mitigate the unsanitary practice of wound sucking. Modern technology now employs systems that range from simple manually actuated pumps (“mechanical” NPWT) or electrically powered and control system-regulated pumps … read more

Nurse creates app to help home health workers care for wounds virtually

Bri-Anna Guillory has worked in home health care for several of her 10 years as a licensed vocational nurse. Since the start of the pandemic, she’s noticed a major uptick in nurses leaving hospitals and joining her field … young nurses often don’t know the best ways to treat pressure sores, ulcers and post-surgical wounds. So Guillory started Divine Healthcare Consultants, which specializes in virtual wound care consulting … read more

Swift Medical Unveils Next-Generation Technology to Make Healthcare More Accessible for Everyone

Swift Medical, the global leader in digital wound care technology, is launching an innovative product that will revolutionize the future of healthcare … Today at 2pm EST / 11am PST, Swift Medical’s co-founder and CEO Carlo Perez will host a live broadcast from the TIFF Bell Lightbox in Toronto. At this event, Swift Medical will unveil a first-of-its-kind technology that will allow patients to access hospital quality care from anywhere and empower clinicians to prevent wounds before they even happen … Chronic wounds are one of the largest public health crises worldwide, with more than 8.2 million patients suffering from chronic wounds in North America alone. As rates of obesity, diabetes and other chronic conditions skyrocket, the number of patients at risk of developing chronic wounds will continue to rise … read more

How Does Jack Reacher Heal So Fast?

If you’re one of many who have binged Reacher recently ― or read the bestselling books by Lee Child ― you’ve enjoyed lethal weapon Army veteran Jack Reacher delivering his share of wish-fulfillment vengeance in satisfying ways. Even though the character is 6’5″ and essentially a slab of muscle (convincingly played by real-life slab of muscle Alan Ritchson), Reacher does indeed bleed … read more

Reshaping wound care: Evaluation of an artificial intelligence app to improve wound assessment

and management amid the COVID-19 pandemic
Individuals with wounds can be found across all age groups and all health care specialties. Some causes of wounds include trauma, burns, skin cancers, infections or underlying medical conditions such as diabetes.1 Wound care is generally considered a comorbid disease, for example, diabetic foot ulcers, venous leg ulcers, pressure injuries, but despite this, patients are treated in the silo of their medical specialty.1 The impact is that the approaches to wound care may differ between specialties, and currently there is no specialist patient-centred wound care approach … read more

Dried human cultured epidermis accelerates wound healing in diabetic mouse skin defect wounds

The shortage of donor sites for skin grafts is a significant problem for the treatment of severe burn injuries. In such cases, cultured epidermal autograft (CEA), which is a cultured keratinocyte sheet prepared from the patient’s skin, is a promising treatment option1. However, the clinical use of CEA is limited owing to its lower take rate, especially on an infected bed, mechanical fragility, and frequent spontaneous blistering, particularly in the early stages2. In addition, a delay of 3 to 4 weeks, required for the preparation of a CEA, creates a fundamental clinical problem, as it occurs during the life-threatening phase in patients with severe burns … read more

The time is now for stewardship in diabetic foot infections

Diabetes, first described in ancient Egypt, remains at the forefront of health care in modern times. Roughly 537 million adults aged 20 to 79 years are living with diabetes worldwide, a number expected to rise over the next decades … Diabetic complications are vast. Diabetic foot infection (DFI) is a chronic, more severe complication that affects roughly 15% of people with diabetes. DFIs have been associated with decreased quality of life, frequent and prolonged hospitalizations and greater risk for lower extremity amputation … read more

The Role of Early Revascularization and Biomarkers in the Management of Diabetic Foot Ulcers

A Single Center Experience

Diabetic neuropathy and Peripheral Arterial Disease (PAD) are the main etiological factors in foot ulceration. Herein, we report our experience of diabetic foot ulceration (DFU) management, with an analysis of the relationship between the rate of lower extremity amputation, in persons with infected DFU, after revascularization procedures performed to prevent major amputation. This study highlights the role of different biomarkers, showing their usefulness and potentiality in diabetic foot ulcer management, especially for the early diagnosis and therapy effectiveness monitoring. A retrospective analysis, from September 2016 to January 2021, of diabetic patients presenting diabetic foot with DFU, was performed. All patients were treated with at least one vascular procedure (endovascular, open, hybrid procedures) targeting PAD lesions … read more

Debridement – Module from Wound Care Today

Debridement is a key component of wound bed preparation for acute and chronic wounds because it helps to improve conditions at the wound bed to encourage healing. This, in turn, helps to reduce the risk of infection and improve patient quality of life.
Debridement … read more

Top 5 Tips for Marketing Your Practice to Diabetic Patients

When doctors ask how they can expand their practice without adding additional nail care patients, most of them cringe when I say to focus their marketing efforts on diabetic patients. Diabetic patients are the fastest-growing patient population for podiatrists. They are the patients that need you the most and can financially benefit your practice when you prescribe/dispense diabetic shoes, perform ABI/PVR testing, treat diabetic wounds, and dispense wound care supplies. If you are ready to get started but not sure of the next steps, here are my top five tips for marketing your podiatric practice to diabetic patients … read more
From AMERX Health Care

MolecuLight Featured in Unprecedented 32 Presentations and Posters at World Union of …

Wound Healing Societies (WUWHS) 2022 Conference
NEWS PROVIDED BY

MolecuLight
Mar 01, 2022, 06:13 ET

 

Wide-Spread Clinical Evidence using the MolecuLight i:X Platform Reveals its Significant Global Adoption and Proven Utility in Wound Care

 

TORONTO and ABU DHABI, United Arab Emirates, March 1, 2022 /PRNewswire/ – MolecuLight Inc., the leader in point-of-care fluorescence imaging for real-time detection of wounds containing elevated bacterial loads, announces that its MolecuLight wound imaging platform is featured in an unprecedented 32 presentations and posters at at the World Union of Wound Healing Societies (WUWHS) 2022 Annual Conference, being hosted from March 1 – 5, 2022 in Abu Dhabi, United Arab Emirates. Held every 4 years, WUWHS is the largest global wound care conference with over 6,500 wound care professionals expected to attend in-person as well as virtually this week.

 

“We are humbled by the number of clinicians globally that have made our MolecuLight point-of-care device an invaluable tool in their wound care practices,” says Anil Amlani, MolecuLight’s CEO. “The impressive collection of 32 talks and posters from so many facilities across 6 countries shows how the MolecuLight imaging device is becoming a new standard-of-care in wound care. This clinical evidence is echoed in the 55+ peer-reviewed publications that include data collected from over 1,400 patients, showing the significant benefit of the MolecuLight i:X® and DX™ to clinical wound assessment and practice.”

 

“The evidence is definitive. The MolecuLight imaging platform is a “must have” device for wound care clinics. The abundance of published clinical evidence showing improvements in bioburden detection, better clinical decision making, and improved outcomes is clear validation for its medical necessity,” says Dr. Thomas Serena, the Founder and Medical Director of The SerenaGroup® and author and presenter of 15+ talks and posters featuring MolecuLight at WUWHS 2022. “There is real clinical benefit for using the MolecuLight alongside a broad range of wound care procedures, in all wound care settings. Evidence now proves that clinical signs and symptoms under perform and contribute to haphazard prescribing of antimicrobials and antibiotics. Used concurrently, information from MolecuLight images is flagging at risk wounds earlier. This leads to improved wound management, reduced antibiotic overprescribing, fewer infection complications, and faster healing.”

 

The collection of 16 presentations and 16 posters featuring the MolecuLight imaging devices show how the devices inform clinical decision-making through the real-time detection of elevated bacterial burden in wounds. They span the wound care continuum, including detection of bacteria within biofilm, wound cleansing and hygiene, antimicrobial stewardship, and impact on detecting surgical site infections. They also include health economic benefits and wound healing results accelerated by RCT-accelerated findings. The results being presented illustrate the significant clinical improvements to wound care outcomes provided by the MolecuLight platform.

 

A selection of the clinical posters and presentation featuring the MolecuLight i:X from World Union of Wound Healing Societies (WUWHS) 2022 Annual Conference 2022 are as follows:

(a)  Select Clinical Posters citing the MolecuLight point-of-care device include:

  • Uncovering the high prevalence of bacterial burden in surgical site wounds with point-of-care fluorescence imaging
    Kylie Sandy-Hodgetts et al., School of Biomedical Sciences, Pathology and Laboratory Science, University of Western AustraliaPerth, Australia
    Download poster

  • The use of an advanced fluorescence imaging system to target wound debridement, decrease bioburden, improve healing rates, and provide positive revenues in an outpatient wound care setting
    Windy Cole, DPM et al., Kent State University College of Podiatric Medicine. Kent OH
    Download poster

  • RCT Evaluating Impact of Routine Fluorescence Imaging of Bacteria on DFU Healing Rates
    Alisha Oropallo, MD et al., Northwell Comprehensive Wound Health Center and Hyperbarics, Lake Success NY
    Download poster

  • Wound Assessment Paradigm Shift: A 350-Patient Multisite Clinical Trial Incorporating Bacterial Fluorescence Imaging into Standard of Care
    Thomas Serena MD FACS MAPWCA FACHM et al., SerenaGroup Research Foundation, Cambridge, Massachusetts, USA
    Download poster

(b) Select Clinical Presentations citing the MolecuLight point-of-care device include:

  • Early detection of wound infection: advances in diagnostics
    Dr. Thomas Serena
    (Tuesday, March 1, 20228:40 AM – 8:50 AM as part of Society Meeting – International Surgical Wound
    Complications Advisory Panel (ISWCAP)), Hall 4 (Part B)

  • Wound hygiene: which cleansing agents and techniques are most effective?
    Session #FC 05B – ID 205/(N)
    Alisha OropalloMD
    (Wednesday, March 2, 202204:00 PM – 06:00 PM) Capital Suite 5

  • Tissue saving approach by guided debridement with fluorescence imaging – or how to treat a sternal surgical site infection with pseudomonas aeruginosa
    FC 78 – ID 275
    Heinrich Rotering, MD
    (Wednesday, March 2, 202202:15 PM – 03:30 PM), Capital Suite 7

  • Optical detection of bacteria: changing the paradigm
    Dr. Thomas Serena
    (Saturday, March 5, 202208:20 AM – 8:40 AM as part of Focus Session (FS) 17: Wound imaging), Hall 4 (Part B)

The complete listing of the 32 presentations & posters is available here.

In additional to the clinical posters and presentations at WUWHS 2022, the MolecuLight i: and DX™ imaging devices will be available for demonstration in the MolecuLight booth #A-06 in the Exhibit Hall at the Abu Dhabi National Exhibition Centre (ADNEC) in Abu Dhabi, UAE.

The MolecuLight i:X® and DX™ imaging systems are the only imaging devices for the real-time detection of elevated bacterial burden in wounds that are FDA cleared and CE and Health Canada Approved. With over 2,000 systems sold, they are commercially available and used by leading wound care facilities globally.

About MolecuLight Inc.
MolecuLight Inc. is a privately-owned medical imaging company that has developed and is commercializing its proprietary fluorescent imaging platform technology in multiple clinical markets. MolecuLight’s suite of commercially released devices, including the MolecuLight i: and DX™ fluorescence imaging systems and their accessories, provide point-of-care handheld imaging devices for the global wound care market for the real-time detection of wounds containing elevated bacterial burden (when used with clinical signs and symptoms) and for digital wound measurement. MolecuLight procedures performed in the United States can benefit from an available reimbursement pathway including two CPT® codes for physician work to perform “fluorescence wound imaging for bacterial presence, location, and load” and facility payment for Hospital Outpatient Department (HOPD) and Ambulatory Surgical Center (ASC) settings through an Ambulatory Payment Classification (APC) assignment. The company is also commercializing its unique fluorescence imaging platform technology for other markets with globally relevant, unmet needs including food safety, consumer cosmetics and other key industrial markets.

www.moleculight.com

Biofilm Module

Biofilm is thought to be present in all chronic wounds. Understanding what biofilm is and how to manage it is important to avoid delayed healing.
Biofilm … read more

Preventing complications at wound dressing changes

This module aims to make clinicians aware of:

  • The importance of skin health and what makes it vulnerable to damage.
  • The damage that can occur when using medical adhesives and improper removal techniques.
  • The impact that MARSIs (medical adhesive-related skin injuries) can have on patients.
  • Ways to reduce the risk of MARSIs by providing appropriate treatment for at-risk patients groups.

read more

Wound Care Service Development Over a Five-Year-Period of National Change

Role of Partnership Working and Education Delivery
This article outlines the development of a community tissue viability service over the same five-year-period in which a number of national issues with wound care were identified through research. These included a lack of evidence-based practice, a changing community workforce and an unwarranted variation in care attributed to a lack of education and training among generalist practitioners. The author describes how a proactive approach was taken to local service development to address these issues, and how partnership working with both colleagues and industry enabled improved wound care education delivery and uptake among a generalist community workforce … read more

Analysis of Bias Criteria Checklist for Wound Care Registries & EHRs

Chronic wounds affect nearly 15% of Medicare patients (8.2 million people) and may cost as much as $96.8 billion per year. The most common are not venous or diabetic, even though they are the most often studied in prospective trials. The most common chronic wounds are surgical incisions that dehisce and the “wounds with no name” due to the patients’ underlying medical conditions. That is because wounds are not a disease – they are a symptom. The US Wound Registry (USWR), a 501 (c)(3) non-profit organization, has been a patient registry since 2005. Since 2014, the USWR has been recognized by the Centers for Medicare and Medicaid Services (CMS) as a Qualified Clinical Data Registry (QCDR) that collects medical and/ or clinical data for the purpose of improving the quality of patient care. While we understand that randomized, controlled trials are needed to demonstrate efficacy in a perfect world, real-world patients have an average of 6 serious co-morbid conditions and take 10 medications. These complicated patients are invariably excluded from clinical research studies, which makes it impossible to know what treatments work best. We believe the way to demonstrate effectiveness in the real world is by using real-world data … read more

Latest Clinical Evidence Presented at APWCA’s Wound Week™ 2022 Illustrates the Significant …

Clinical Utility of the MolecuLight Point-of-Care Imaging Platform
PRESS RELEASE
February 24, 2022

Toronto, ONTARIO and Philadelphia, PENNSYLVANIA – (February 24, 2022) MolecuLight Inc., the leader in point-of-care fluorescence imaging for real-time detection of wounds containing elevated bacterial loads, announces the presentation of 8 Clinical Posters and a Presentations and a Hands-On Workshop at the American Professional Wound Care Association’s (APWCA) Wound Week™, held from February 24 – 27, 2022 in Philadelphia, PA. Wound Week is a leading multidisciplinary meeting of wound care professionals that presents cutting-edge clinical findings and best practices presented by its expert faculty.

“We are thrilled with the significant number of presentations and posters at Wound Week showing the impressive results derived from MolecuLight point-of-care devices,” says Anil Amlani, MolecuLight’s CEO. “The clinical insights that are informed by the MolecuLight platform span the wound care continuum, including wound cleansing and hygiene, antimicrobial stewardship, detection of wound-related cellulitis and surgical site infections. The outcomes presented in these studies illustrate the significant clinical improvements to wound care provided to clinicians by the MolecuLightplatform”.

The 8 clinical posters and the presentation featuring the MolecuLight i:X at Wound Week 2022 are as follows:

Posters by Dr. Alisha Oropallo (Northwell Comprehensive Wound Healing Center and Hyperbarics, Lake Success NY) include:

  • Wound Hygiene: Which Cleansing Agents and Techniques Are Most Effective?
     Download poster
  • 12-week RCT Evaluating Impact of Routine Fluorescence Imaging of Bacteria on DFU Healing Rates
     Download poster

Posters by Dr. Charles Andersen (Vascular/Endovascular/Limb Preservation Surgery Service, Madigan Army Medical Center, Joint Base Lewis-McChord, WA) include:

  • Diagnosis and Treatment of the Invasive Extension of Bacteria (Cellulitis) from Chronic Wounds Utilizing Point-of-Care Fluorescence Imaging
     Download poster
  • Guidelines for point-of-care fluorescence imaging for detection of wound bacterial burden based on Delphi consensus
     Download poster

Posters by Dr. Thomas Serena (SerenaGroup Research Foundation, Cambridge, MA) include:

  • Reliance on Clinical Signs & Symptoms of Bacterial Burden in Chronic Wounds Leads to the Misuse of Antimicrobials: Analysis of the FLAAG Clinical Trial
     Download poster
  • Point-of-care fluorescence imaging enhances detection of high bacterial burden in surgical site wounds
     Download poster
  • Are Semi-Quantitative Clinical Cultures Inadequate? Comparison to Quantitative Analysis of 1053 Bacterial Isolates from 350 Wounds
     Download poster
  • An image is worth 10,000 microbes: How fluorescence imaging augments IWGDF criteria for detection of bacterial burden in diabetic foot ulcers
     Download poster

The Clinical Presentations citing the MolecuLight point-of-care device is:

  • All That Glows is Not Good (Innovative Technologies: What’s in the Pipeline?)  by Dr. Oropallo on Sat., Feb. 26, 2022, 9:00 – 10:00 am in the Commonwealth Room

In addition to the clinical posters and presentations at Wound Week,, the MolecuLight i:X® and DX™ imaging devices will be demonstrated at the Hands-On Workshop on Thursday, February 24th from 1:30 pm – 5:30 pm in the Regency B Ballroom. They will also be available for demonstration in the MolecuLight booth #36 in the Exhibit Hall at the Loews, Philadelphia, PA.

 

About MolecuLight Inc.

MolecuLight Inc. is a privately-owned medical imaging company that has developed and is commercializing its proprietary fluorescent imaging platform technology in multiple clinical markets. MolecuLight’s suite of commercially released devices, including the MolecuLight i:X® and DX fluorescence imaging systems and their accessories, provide point-of-care handheld imaging devices for the global wound care market for the real-time detection of wounds containing elevated bacterial burden (when used with clinical signs and symptoms) and for digital wound measurement.  MolecuLight procedures performed in the United States can benefit from an available reimbursement pathway including two CPT® codes for physician work to perform “fluorescence wound imaging for bacterial presence, location, and load” and facility payment for Hospital Outpatient Department (HOPD) and Ambulatory Surgical Center (ASC) settings through an Ambulatory Payment Classification (APC) assignment. The company is also commercializing its unique fluorescence imaging platform technology for other markets with globally relevant, unmet needs including food safety, consumer cosmetics and other key industrial markets.

 

For more information, contact:

Rob Sandler
Chief Marketing Officer
MolecuLight Inc.
T. +1.647.362.4684
rsandler@moleculight.com
www.moleculight.com

Leg wounds: topical timolol accelerated healing times in elderly patients

Managing a surgical wound on the lower leg can be a challenge. Often, higher wound tension, atrophic skin, edema, and compromised circulation result in higher risks of wound dehiscence and infection, and significantly limit the capacity of wound closure post-surgically. Therefore, healing by secondary intention is a practical option for many lower leg Mohs defects. However, a secondary intention wound on the lower leg is expected to take a longer time to heal. Certain factors such as older age and health conditions of the host may adversely affect healing time … Timolol is a nonselective beta-adrenergic receptor antagonist that has FDA approval for the treatment of glaucoma. In addition to this FDA-approved indication, topical timolol has several off-label uses in dermatology, such as for the treatment of infantile hemangiomas, venous stasis ulcers, and refractory wounds. Although timolol solution has been used in chronic wounds … read more

Custom-made indoor footwear may be beneficial for people with diabetes at risk for ulceration

“Custom-made footwear is an effective intervention to help prevent foot ulceration and is recommended in international guidelines,” but ensuring consistent use is “a challenge,” particularly indoors, explain Sicco Bus and co-authors from Amsterdam University Medical Center in the Netherlands … To address this issue, the researchers carried out a study of 31 people with type 1 (23%) or type 2 (77%) diabetes with moderate-to-high risk for plantar foot ulceration who already possessed custom-made footwear prescribed by a rehabilitation medicine specialist. These people were provided with additional custom-made footwear specifically designed for indoor use, with the same biomechanical offloading capacity as their existing footwear … read more

Fast Five Quiz: Type 2 Diabetes and Peripheral Artery Disease

According to the International Diabetes Federation, 537 million people around the world have diabetes. This number is projected to rise to 700 million by 2045. In 2021, diabetes was responsible for 6.7 million deaths. Type 2 diabetes accounts for around 90% of diabetes cases, making it a global health crisis. Peripheral arterial disease (PAD) is an athero-occlusive disease and a chronic complication of diabetes. It is a risk factor for both foot ulceration and amputation. More than two thirds of patients with diabetic foot ulceration have associated PAD. Estimates suggest that more than 230 million people worldwide have PAD. Early recognition and treatment of patients with diabetes and feet at risk for ulcers and amputations can prevent or delay adverse outcomes … read more

New Updates on the Diabetes Epidemic Within the United States

A recent report from the Centers for Disease Control (CDC) revealed startling new updates to the number of individuals with diabetes and prediabetes in the United States. The data obtained from 2017-2020 showed that one in ten Americans have diabetes, and over one-third have prediabetes. It also mentioned that of the 37.3 million people with diabetes, around 8.5 million are undiagnosed. This was similar in those with prediabetes: of the 96 million adults that have it, approximately 19% are unaware of their prediabetes status. In addition, an even more alarming aspect of the finding was the substantial rise in diabetes and prediabetes in young adults and even children … read more

Helping to prevent pressure ulcers

A quick guide for registered managers of care homes

A healthcare professional should reassess a person’s pressure ulcer risk:

  • after surgery or other investigation
  • if they move to a different care setting
  • if their underlying condition worsens
  • after a change in their mobility.

If the person has several risk factors or a history of pressure ulcers, they should be assessed as being at high risk of developing a pressure ulcer. A trained healthcare professional should complete a skin assessment for anyone assessed as high risk … read more

Wound Cleansing With a Hypochlorous Acid–Preserved Wound Cleanser in Pediatric Patients With Burns

Wound cleansing and wound bed preparation is an important step toward healing of any wound etiology. A hypochlorous acid–preserved wound cleanser (HAPWOC; Vashe, Urgo Medical) is used widely across the continuum of care in the author’s large hospital system, which includes a pediatric burn unit. HAPWOC is used widely in inpatients and outpatients for acute and chronic wounds, including burns. Its use is of particular importance when wound bioburden is a consideration … read more

Why the Current State of Wound Care Research Makes Me Mad ….

and How You Can Help Fix it at the Wound Care Evidence Summit
The Wound Care Evidence Summit will take place May 19-20, 2022 at the Hyatt Regency Bethesda, MD. If you are involved in the field of wound care (e.g., Chief Medical Officers, researchers, Regulatory Affairs staff, Clinical Association representatives, manufacturers, etc.) you need to register now because spots are limited. The meeting will convene commercial and government payer medical directors, the FDA, NIH senior staff, wound care researchers, manufacturers, and policymakers.

Here’s why I care about this so much: In about 1997, I was one of several investigators participating in the prospective clinical trial of Becaplermin (REGRANEX®) Gel for Diabetic foot ulcers (DFUs). That trial enrolled mostly Wagner 1 DFUs and Wagner Grade 2 DFUs (as long as the Wagner 2 DFUs had no exposed tendon, capsule or bone – which means, not really Wagner 2 DFUs). In addition to studying … read more

Microbiological Identification and Resistance Profile of Microorganisms in Pressure Injuries

After the Use of Polyhexamethylene Biguanide: A Series of Fourteen Cases
Introduction. Colonization of a pressure injury with microorganisms can negatively affect wound healing. Thus, it is necessary to evaluate which products best facilitate wound healing. Objective. This case series evaluated the effectiveness of the antimicrobial polyhexamethylene biguanide (PHMB) on microorganisms in pressure injuries. Materials and Methods. Fourteen patients (14 wounds) were treated with PHMB in the hospital setting after collection of a wound swab sample for microbiological analysis and determination of the risk profile using the disk diffusion method. Results. Thirteen lesions (92.9%) were positive for 1 or more bacterial strains, the most prevalent of which were Staphylococcus aureus and Pseudomonas aeruginosa. Two strains of methicillin-resistant S aureus (MRSA) were also identified. Klebsiella pneumoniae demonstrated 100% resistance to the tested antibiotics, with Acinetobacter demonstrating 90% resistance … read more

35 Years of Pressure Injury Science and Knowledge Translation

Our celebratory 35th publication year continues with our fourth annual themed issue on pressure injuries (PIs), an important global concern.

This issue provides recent PI research in print and online from the US and around the world. Some of the international authors’ contributions include the following:

  • Finnish data on PI prevention
  • A study from Turkey on managing PIs in home care
  • Brazilian research on PIs in ICU patients.

read more

Epigenetics and Biochemistry of Stress in Wound Care

Wound care can be a surprisingly emotional field. Some days it can feel like every patient visit contains challenging emotional situations that clinicians must also recover from with resilience not to carry that energy to the next visit. These stressors can be related to the patient’s medical status and critical conversations regarding their health, pain and anxiety, the death of a patient’s close family members, and even access to basic necessities like safe housing and social support. Factors other than the health care they receive are driving outcomes, consistent with what we know about social determinants of health which determine 80% of health outcomes. These life stressors and the stressors that have occurred throughout the patient’s life can contribute to physiologic changes that further delay wound healing … read more

NHG programme for diabetic foot disease reduces major amputations by 40 per cent

An innocuous injury to his left little toe in late 2019 led to an infection that resulted in nine foot-related operations and five lower limb angioplasties in just over a year for Mr Toh Eng Cheng. His gangrenous toe had to be amputated, and another six later, to curb a recurrence of diabetic foot ulcers, but the 52-year-old counts himself lucky. “I could have lost the lower part of my leg or maybe the whole leg,” said the former security supervisor, who has three toes left on his right foot. “Of course, I did not like the idea of amputating my toes at first,” he told The Straits Times. “But if I didn’t accept it, then who knows, I might not be talking to you now,” he said. He added that he is glad he is still able to walk without the need for a walking frame or walking stick … read more

Increased temperature at the healed area detected by thermography predicts recurrent pressure ulcers

Preventing recurrent pressure ulcers is an important challenge in healthcare. One of the reasons for the high rate of recurrent pressure ulcers is the lack of assessment methods for their early detection. Therefore, this study aimed to determine the thermographic characteristics of the healed area and to consider the predictive validity of thermographic images for recurrent pressure ulcers within a 2-week period. This observational study was conducted at a long-term care facility in Japan between July 2017 and February 2019 among patients whose pressure ulcers had healed. Thermographic images of the healed area were recorded once a week until recurrence or until the end of the study. We enrolled 30 participants, among whom 8 developed recurrent pressure ulcers. The generalised estimation equation revealed that the thermographic finding of increased temperature at the healed area compared to that of the surrounding skin was significantly associated with recurrent pressure ulcers … read more

Foundations of Best Practice for Skin and Wound Management – E-book

Foundations of Best Practice for Skin and Wound Management is a comprehensive document intended to help health-care professionals in the prevention and management of wounds … Developed by teams of interprofessional experts with a deep wealth of knowledge and experience, the chapters that make up Foundations have been built using a rigorous process of researching, writing and reviewing. Each chapter provides a best practice approach to the prevention and management of a particular wound type, except the first two, which offer a broad overview of skin physiology and wound healing and the prevention and management of wounds in general … order

Chronic Wounds: Economic Impact & Costs to Medicare

A new study, “An Economic Evaluation of the Impact, Cost, and Medicare Policy Implications of Chronic Nonhealing Wounds,” published in the International Society For Pharmacoeconomics and Outcomes Research’s Value in Health journal (Jan. 2018) demonstrates the economic impact and full burden of chronic nonhealing wounds in the Medicare population. The study analyzed the Medicare 5% Limited Data Set for CY2014 to determine the cost of chronic wound care for Medicare beneficiaries in aggregate, by wound type, and by setting. Topline findings show that chronic wounds impact nearly 15% of Medicare beneficiaries … read more

Called to the Principal’s Office: My Experience With a TPE Audit

One day, as medical director of three wound centers—two with hyperbaric services in a five-hospital system—I was called to the wound care administrator’s office. I heard the three things that I never wish to hear going into a meeting:

1.    “Please come to my office and close the door.”

2.    “I would like to give you a heads-up.”

3.    “You are being audited by Medicare for a targeted probe and educate.”

read more

Iranian firm produces, exports advanced wound dressings

An Iranian knowledge-based company has produced advanced wound dressing products, with structures similar to human skins
Wound dressings are important because wounds and damaged tissues go through a relatively-complicated and time-consuming process to heal. And using low-quality products could lead to infection or scars on the skin after wounds heal.

The products manufactured by Teba Zist Polymer (Treetta) company, after eight years of research and development, use a host of technologies to ensure quick and seamless healing of wounds … read more

Does HBOT promote the healing of diabetic foot ulcers?

Hyperbaric oxygen therapy (HBOT) is a treatment option that involves a person breathing almost pure oxygen in a special room or small chamber. Evidence suggests that HBOT may have a variety of applications, including the promotion of wound healing. Due to this, it may help treat diabetic foot ulcers … During the natural wound healing process, the body uses oxygen to stimulate the healing and growth of new tissue. HBOT helps encourage the formation of new blood vessels around the wound area, and these supply the area with more oxygen. This influx of oxygen and other healing nutrients helps generate new, healthy tissue … read more

Free Triiodothyronine and Free Triiodothyronine to Free Thyroxine Ratio Predict

All-Cause Mortality in Patients with Diabetic Foot Ulcers
Purpose: Free triiodothyronine (FT3) and FT3/free thyroxine (FT4) ratio have been associated with mortality in various diseases. However, no study to date has identified a link between FT3, FT3/FT4 ratio and all-cause mortality in patients with diabetic foot ulcers (DFUs). This study aimed to investigate this relationship.
Methods: This retrospective cohort study included 726 patients diagnosed with DFUs in a public hospital from January 2015 to October 2019. Patients were classified by the optimal cut-off values of the FT3 and FT3/FT4 ratio, respectively. The association of FT3 and FT3/FT4 ratio with all-cause mortality was evaluated in a multivariable cox regression model. Directed acyclic graphs were used to assess the minimally sufficient sets of confounding variables … read more

Peer-Reviewed Study Demonstrates Increased Cost-Effectiveness of MIMEDX

Dehydrated Human Amnion Chorion Membrane (DHACM) in Lower Extremity Diabetic Ulcer (LEDU) Treatment Compared to Standard of Care
Use of MIMEDX PURION® Processed DHACM Provided Improved Clinical Benefits, Shorter Average Length of Treatment and Increased Quality-Adjusted Life Years
MiMedx Group, Inc. (Nasdaq: MDXG) (“MIMEDX” or the “Company”), a transformational placental biologics company, today announced the publication of a peer-reviewed study in the Journal of Wound Care evaluating the cost-effectiveness of the Company’s PURION® processed dehydrated human amnion/chorion membrane (DHACM) allografts (EPIFIX®) compared with standard of care for treating lower extremity diabetic ulcers (LEDUs), including diabetic foot ulcers (DFUs).

The study analyzed a retrospective cohort (2015-2019) of 10.9 million Medicare patients diagnosed with diabetes, 1.2 million of whom had a LEDU, and tracked outcomes such as amputations and healthcare utilization. Findings across propensity-matched cohorts demonstrated that the timely use of DHACM resulted in a significant reduction in long-term healthcare related costs, driven by the associated improved clinical benefits indicated by patients receiving DHACM, compared to those receiving standard of care, or receiving no advanced treatment (NAT) … read more

Outcomes of Telehealth for Wound Care: A Scoping Review

The aim of this scoping review is to synthesize the literature on delivering wound care via telehealth and compare clinical, healthcare utilization, and cost outcomes when wound care is provided via telehealth (telewound) modalities compared to in-person care … read more

SMART researchers discover unique lysin capable of killing deadly multidrug-resistant bacteria

Novel lysin Abp013 has shown promising antimicrobial ability against Acinetobacter baumannii and Klebsiella pneumoniae

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, alongside collaborators at Nanyang Technological University, have identified a novel phage lysin – Abp013 – that could be used as an alternative antimicrobial agent against two of the most deadly bacteria: Acinetobacter baumannii and Klebsiella pneumoniae. The study is supported by the National Research Foundation (NRF) Singapore, under its Intra-CREATE Collaborative Seed Grant … Antimicrobial resistance remains an ever-growing threat to humankind, and an increasing number of people die each year from superbug infections. The development of new bacteria-killing agents is crucial, and lysins have shown great promise in treating deadly chronic wound and lung infections against which no antibiotics are effective … read more

MediWound awarded a U.S. Department of Defense research grant for the development of Nexobrid for the U.S. Army

Research project award is for the development of Nexobrid as a non-surgical solution for field care
YAVNE, Israel, February 17, 2022 — MediWound Ltd. (Nasdaq: MDWD), a fully-integrated biopharmaceutical company focused on next-generation bio therapeutic solutions for tissue repair and regeneration, today announced that the U.S. Department of Defense (DoD), through the Medical Technology Enterprise Consortium (MTEC), has awarded MediWound a $1.7 million research project for the development of NexoBrid® as a non-surgical solution for field-care burn treatment for the U.S. Army (the “MTEC Research Project Award”).

“We are privileged to join forces with the U.S. DoD, supporting its goals of improving treatment outcomes and saving lives of service members who suffer traumatic burn injuries in the battlefield,” said Sharon Malka, Chief Executive Officer of MediWound. “This non-dilutive funding provides important recognition of NexoBrid’s merits as a non-surgical, easy-to-use, effective solution for eschar removal of severe burns and highlights its potential role in treating severe burn injuries in the field as early as the point of injury. We thank the U.S. Army Medical Research and Development Command (USAMRDC) for the award and look forward to working with them to have NexoBrid available for military use by the U.S. Army.”

“The military services require simple and effective non-surgical solutions to treat severe burn patients as close to point of injury as possible. MTEC is excited to support MediWound’s effort to advance an effective non-surgical debriding solution for far forward burn treatment to benefit U.S. service members. This work could result in a transformational change to the current standard of care of burn injuries,” stated Lauren Palestrini, PhD, MTEC Director of Research Programs … read more

Creating a Crash-Proof Retirement for Doctors

Can your portfolio weather fickle market fluctuation?
To the uninitiated, a crash proof retirement can seem like a white whale — impossible to capture. That’s because to most physicians, investing in general seems like such a risky endeavor, best left to financial advisors or financial planners. That is how the financial industry makes a lot of its money. However, once you begin your financial education and learn the simple investing strategies that will lead you to financial freedom … read more

How a Dumpster Inspired a Wound Center Revolution

About 25 years ago I was hired to assist a wound center in Sherman Oaks as it moved away from its management company, Curative. It was one of the first instances of a hospital insourcing their wound center and canceling their management contract. To say that the process was contentious would be a gross understatement. On my first day, two program directors from other local wound centers run by Curative, showed up at the facility to take everything that belonged to the company … read more

Scoop of Practice Episode 1: Designing a Wound Career

During my reflections on my Designing Your Life1 immersion experience I referenced my mother’s great words of wisdom: “if you love your profession then it really isn’t work. If you put your best foot forward and work hard you can achieve miracles.” … Choosing to become a doctor was not a difficult decision at all. Perhaps growing up with a father whose passion in life was to study the inner workings of a car to fix a malfunction underlay my own fascinations with what is going on under the hood. My mother was a medical administrator and because of my parents’ examples as compassionate and dedicated life mentors, I am the person I am today. I also draw upon my work mentors as I travel along my odyssey … read more

Spray with Nitric Oxide Donor Accelerates Wound Healing: Potential Off-the-Shelf Solution for Therapy?

Nitric oxide (NO) is a highly active gaseous signaling molecule that is synthesized by NO synthases and mediates many physiological processes, from vasodilation to signal transmission in neurons. In addition, NO has a bactericidal effect, the ability to activate cellular and humoral immunity, induces the proliferation and synthetic activity of fibroblasts, activates the proliferation of keratinocytes and the antioxidant system. The variety of these effects provides NO comprehensive effect in various stages of wound healing and accelerates regeneration. Currently, there are three distinct ways for increasing the concentration of NO in wound tissues: the application of inductors of NO synthesis, NO-containing gas flows, and donor molecules. Using NO donors is one of the most promising and actively developing areas because of the large variety of donor chemical compounds … read more

Letter to Noridian: Wound and Ulcer Care LCD/LCA

The Alliance submitted a letter requesting that Noridian revise it Wound and Ulcer Care LCD (L38904) and LCA (A58567) to ensure that that CPT and HCPCS code descriptors are correct and to update incorrect/outdated terminology within the policy. The Alliance submitted a detailed list of suggested revisions … read more (available to Alliance members only)

Old and New Pearls for Wound Healing

This old pearl is as pertinent as ever, Kirsner said. While there are many available products on the market for wound healing, dermatologists need to use evidence-based therapies, especially when considering which of the more than 80 cell- and tissue-based products would benefit the individual patient most. Examples of those products with evidence include bi-layered cellular products … read more

Pressure Injuries (Pressure Ulcers) and Wound Care

Although the terms decubitus ulcer, pressure sore, and pressure ulcer have often been used interchangeably, the National Pressure Injury Advisory Panel (NPIAP; formerly the National Pressure Ulcer Advisory Panel [NPUAP]) currently considers pressure injury the best term to use, given that open ulceration does not always occur. [1] According to the NPIAP, a pressure injury is localized damage to the skin and underlying soft tissue, usually over a bony prominence or related to a medical or other device. It can present as intact skin or an open ulcer and may be painful. It occurs as a result of intense or prolonged pressure or pressure in combination with shear … read more

Effects of physical activity as an adjunct treatment on healing outcomes and

recurrence of venous leg ulcers: A scoping review
Healing time is protracted and ulcer recurrence is common in patients with venous leg ulcers. Although compression is the mainstay treatment, many patients do not heal timely. Physical activity may be a clinically effective adjunct treatment to compression to improve healing outcomes. This scoping review provides a broad overview of the effect of physical activity as an adjunct treatment to compression on wound healing and recurrence. We followed the six-step framework developed by Arksey and O’Malley. We searched electronic databases and trial registration websites for relevant studies and ongoing trials. Two authors independently screened and selected articles. Findings were presented in a descriptive statistical narrative summary. We consulted and presented our findings to the wound consumer group to ensure the relevance of our study. Physical activity interventions in 12 out of the 16 eligible studies consisted of only one component, eight studies were resistance exercises … read more

Using Augmented Reality to Improve Patient Outcomes With Negative Pressure Wound Therapy

Digital technology is already immensely integrated within health care, but new innovations in this space could result in unconventional opportunities to improve patient outcomes. Augmented reality (AR), which is the enhancement of reality by virtual content, is one such innovation.1 Augmented reality has many uses in health care, such as education, remote viewing, and hands-free imaging and/or data retrieval.2 The AR device uses a heads-up display, which allows for information to be relayed and displayed in real time to the wearer via an Internet-connected device. The integrated cameras in the device enable the wearer to virtually livestream their point of view. The use of AR to virtually assess wounds has been found to have promising reliability … read more

Antimicrobial Stewardship In Wound Care

Antimicrobial resistance (AMR) is now one of the leading causes of death around the world. The World Health Organization (WHO) has declared that AMR is one of the top 10 global public health threats facing humanity. The inappropriate use of antimicrobial drugs contributes to AMR and adverse events, and improving antimicrobial prescribing practices is a patient safety priority.[5] In 2013, the Centers for Disease Control and Prevention (CDC) estimated that at least 2 million illnesses and 23,000 deaths per year were caused by antibiotic-resistant bacteria in the United States. A more recent study estimated that in 2019, 44,800 deaths were directly caused by AMR and 186,000 deaths were associated with AMR in North America … By default, chronic wounds are contaminated by several types of bacteria. When the host (patient) does not adequately respond to bacterial contamination, this contamination can turn into colonization, which can further turn into infection. Wound infections are often caused by bacteria that are becoming increasingly resistant to common antibiotics due to antibiotics misuse and/or overuse.[2][3] It is thus imperative that antibiotic prescribing practices evolve such that antibiotics are prescribed only when they are essential … read more

Practice Management Education Opportunities February 23, Austin, TX

Take the first few steps to coding and billing by joining us for a comprehensive workshop covering the fundamentals of coding and billing for foot and ankle surgeons. Learn the foundation of the coding and billing process from expert colleagues before taking the ACFAS Coding and Billing for the Foot and Ankle Surgeon course. This course is for residents, fellows, new practitioners, office staff of foot and ankle surgeons or anyone who wants to learn more of the basic coding and billing terminology and process. Plus, if you’re a resident and attending Residents Day in the morning the day of the event, this course is a great next step to learning more about coding and billing for your future practice and can be bundled in your pricing … read more

What Do Medical Records Reveal About the Effectiveness of Care for Diabetic Foot Health?

Medical records are frequently the source of clinical data used in research of the diabetic foot. However, due to variations in the records, problems can result in collecting and using the data for such research … Worldwide, there are vast differences in the type of medical record, the quality of the medical record and how providers and or health systems manage the data it contains. Medical records can range from simple, handwritten notes that often include some short cuts or abbreviations, to sophisticated electronic health records. The issues of who collects the data and how it is documented will ultimately influence how it can be harvested, manipulated, and used in research … read more

The use of medical grade honey to achieve healing in an older patient with chronic wounds and

complex co-morbidities: a case report
Aging is associated with an increased likelihood of co-morbidity and other factors that are known to delay wound healing (Gosain and DiPetro, 2004; Bonifant and Holloway, 2019). Additionally, aging itself is a risk factor for chronicity as a consequence of changes in the epidermis and dermis. The dermo-epidermal junction becomes flattened, and elasticity of the skin reduces due to morphological changes in collagen and elastin, which predispose the tissue to shear and friction forces (Gosain and DiPetro, 2004; Bonifant and Holloway, 2019). Moreover, the microcirculation and lymphatic drainage of the dermis is decreased with age, and this affects its ability to adapt to injury and clear the wound of pathogens thus inhibiting wound contraction (Gosain and DiPetro, 2004). Older patients, frequently described in the literature as aged 65 years or above, often have multiple comorbidities, such as poor circulation, poor nutritional and hydration status, and the presence of diseases such as diabetes that affect general health (Leung et al, 2018; Wilkinson and Hardman, 2020). These comorbidities can negatively influence the wound healing trajectory, making vigilance during wound management … read more

UrgoClean Ag in Real Life

In 2019, the International Diabetes Federation (IDF) reported that over 77 million individuals have diabetes in India, which will increase to over 100 million by 2030 (IDF, 2019). Of these people with diabetes, 25% will develop a diabetic foot ulcer (DFU), equating to 5 million by 2030. Overall, half of ulcers become infected during the healing process, necessitating hospitalisation, while 20% of these patients require amputation. DFUs contribute to approximately 80% of all non-traumatic amputations performed annually in India (Ghosh and Valia, 2017). It is indicated that social epidemiology regarding DFU in India differs from the West due to many factors including socio-economic and cultural factors. This can lead to significant delay in specialist referral, with patients still relying on treatment based on local ethnic methods and not based on scientific data. This results in patients presenting with highly infected ulcers (Rastogi and Bhansali, 2016) … read more

‘No difference’ between endovascular, open vascular surgeries for diabetic foot ulcers

Adults with diabetic foot ulcers and peripheral artery disease who receive revascularization surgery are at no greater risk for amputation or death following endovascular surgery compared with open vascular surgery, according to findings published in the Journal of Diabetes and its Complications … “The present large cohort study showed in a propensity score-adjusted analysis that there was no difference in amputation-free survival in patients with diabetic foot ulcers and peripheral arterial disease regardless of whether endovascular or open vascular surgery was chosen as first-line vascular intervention,” Talha Butt, MD, of the department of cardiothoracic and vascular surgery at Skåne University Hospital in Sweden … read more

Diabetic foot ulcers associated with mortality, hospitalization for chronic conditions

Diabetic foot ulcer episodes were associated with all-cause mortality and all-cause inpatient hospital admissions, according to new results published in Diabetes Research and Clinical Practice … “The impact of diabetic foot ulcers has been historically difficult to quantify, but our study shows that these foot wounds are associated with higher rates of all-cause hospitalization and all-cause mortality,” Brian J. Peterson, co-founder and chief scientist at Podimetrics, told Healio. “In our research, we found that during episodes-of-care for diabetic foot ulcers, individuals are 50% more likely to die and nearly three times more likely to be hospitalized.” … read more

Guard Medical Announces FDA 510k Clearance for Additional Sizes of Its Novel NPseal

the First All-in-One NPWT Surgical Dressing
Privately-held company Guard Medical Inc. today announces FDA 510k clearance for additional sizes (10 and 15cm) of its next generation Negative Pressure Wound Therapy (NPWT) dressing NPsealTM for the treatment of closed surgical incisions. NPsealTM is an easy-to-use and cost-effective NPWT surgical dressing with an integrated pump that establishes and maintains negative pressure with just a few pinches … “We’re excited to expand our NPsealTM portfolio, now with the 5, 10 and 15 cm sizes. NPsealTM can now be used on a large percentage of closed surgical incisions across multiple specialties. Receiving FDA clearance for the larger sizes is another significant milestone towards becoming the NPWT dressing of choice for the treatment of surgical incisions,” stated Machiel van der Leest, CEO of Guard Medical. “NPsealTM ease-of-use and cost effectiveness makes, for the first time, prophylactic use of NPWT for all eligible closed surgical incisions possible.” …
read more

Guidelines Highlight Role of Nutrition in Management of Diabetic Foot Ulcers

New guidelines recommend healthcare providers develop and implement an individualized nutrition care plan for individuals with diabetes with or at risk of a DFU
New guidelines endorsed by the American Limb Preservation Society highlighted the importance of nutrition in wound healing for adults with diabetes, who also experience diabetic foot ulcers (DFU).

The guidelines stated that nutritional interventions were “recommended for all patients who could benefit now or in the future from nutritional care.” As such, healthcare providers should develop and implement an individualized nutrition care plan for individuals with or at risk of a DFU, who are additionally malnourished or at risk of malnutrition … read more

Amnio Technology Launches Two New Dual-Layer Allografts

FDA Recognizes Products as Minimally Manipulated, Homologous Use HCT/Ps
Amnio Technology, a global leader in the development of and distribution of amniotic tissue allografts is announcing the launch of two new PalinGen® membrane products, PalinGen® Dual-Layer Membrane and Dual Layer PalinGen® X-Membrane. The new allografts, like the entire family of PalinGen® membrane products, are minimally manipulated, homologous use and chorion-free. The dual-layered nature of the allografts allow for unidirectional application with two outward facing epithelial sides. The proprietary Advantek® process used to manufacture PalinGen® membranes preserves the extracellular matrix components and regulatory proteins present in amniotic tissues. Preserving the characteristics of the natural tissue aids in wound management.

PalinGen® Dual-Layer Membrane and Dual Layer PalinGen® X-Membrane are indicated for patients suffering from non-healing acute and chronic wounds as well as complex and/or open surgical wounds and burns.

Senior Director of New Product Development, Robert Diller, PhD, shared his insight into the motivation for developing a multilayered amniotic product, “The PalinGen® Dual layer membranes have increased durability and slower resorption, which makes them ideal for use in robotic and other surgical applications” … read more

South Korea approves Cuban medicine

In a rare breakthrough into a developed market, the South Korean pharmaceutical regulatory agency approved a Cuban medicine, Cuba’s Center for Genetic Engineering and Biotechnology (CIGB) announced in a tweet.

No further context was immediately available.

According to the CIGB tweet, South Korea’s Ministry of Food and Drug Safety approved Heberprot-P, a biotech product that treats diabetic foot ulcers, for use with Korean patients.

Recombinant human epidermal growth factor-based Heberprot, which was first approved in Cuba in 2006, has been registered in Vietnam, Malaysia, Turkey, Argentina, Colombia, Kuwait, Ukraine, and Russia, among others. An agreement with a U.S. company in 2016 to bring Heberprot-P to clinical testing in the United States seems to have faded … read more

Diabetic Neuropathy, Avoiding Amputation, and Foodie – Blog

Dr. Tea Nguyen podiatrist specializes in diabetic wound care, why educates against the webMD diagnosis, her honest and forward speech to patients, fat relocation advances for surgical outcomes, and shares her martial and daily staff tips and foodie.

Dr. Tea Nguyen is Fellowship trained in wound care particularly with diabetics.

Big reason why diabetics have the wounds that can require amputation is because of peripheral neuropathy and losing the pain sensitivity. One of the problem is a patient doesn’t know a cut may have happened and can’t see it because of back pain or poor vision and therefore they get systemic symptoms or a bad smell before they know something is wrong … listen more

A tool to promote patient and informal carer involvement for shared wound care

Shared wound care encompasses approaches and interventions that enable patients to participate in care planning and delivery, rather than just being a passive recipient of services provided. A key step in facilitating greater shared care is identifying the individuals (patients and informal carers) who would be good candidates to be involved in shared wound care. An international survey was conducted to help identify the characteristics that may indicate an individual’s suitability to participate in shared wound care. The results of which informed the development of a guide that clinicians can use to direct discussion to better understand patient and informal carer suitability for shared wound care and identify the approaches and interventions that may be suited to the patient and informal carer’s needs … read more

5 Wound Care Myths Still in Practice Today

Since WCA was founded 20 years ago, our industry has made great strides and advancements in both technology and method. Unfortunately these changes aren’t always well-known, allowing for less effective and sometimes even harmful practices to continue.

In this blog we’ll cover 5 common myths we still see in wound care treatment and how you can avoid them … read more

Factors associated with adherence to using removable cast walker treatment among patients with …

diabetes-related foot ulcers
Adherence to using knee-high offloading treatment is critical for healing diabetes-related foot ulcers (DFUs). However, few studies have investigated patients’ adherence to using knee-high offloading treatment. We aimed to investigate the levels and factors associated with adherence to using knee-high removable cast walker (RCW) treatment among patients with DFUs … read more

Comparing the standard surgical dressing with dehydrated amnion and platelet-derived …

growth factor dressings in the healing rate of diabetic foot ulcer: A randomized clinical trial
In patients having diabetic foot ulcers, a better-improved healing results from dehydrated amnion dressing than platelet-derived growth factor dressing and surgical debridement … This is a multi-arm parallel-group randomized trial including 243 patients with a minimum 4-week medical history of diabetic foot ulcers with Wagner’s grades 1 and 2, no infection, and adequate tissue blood flow … They were randomized to one of three 81-person groups: surgical debridement (the standard method), dehydrated amnion dressing, or platelet-derived growth factor dressing; and were followed up for 12 weeks … Regarding the type of ulcer, the area of ulcer, Wagner’s grade, the period, and the ulcer’s size, all three study groups were comparable … read more

Animal experimental models of ischemic wounds – A review of literature

Critical limb ischemia is a serious form of peripheral arterial disease (PAD). The consequences of lower limb ischemia are pain, claudication and chronic non-healing wounds. Patients with diabetes are especially at a high risk for developing non-healing ulcers. The most serious complication is major amputation. For this reason, there is a significant medical requirement to develop new therapies in order to prevent the progression of PAD. For research purposes, it is crucial to find an appropriate model of chronic ischemia to explore the processes of wound healing. According to recently acquired information, rodents are currently the most commonly used animals in these types of studies. The main advantage of using small animals is the low financial cost due … read more

TissueTech Announces Rebranding, Adopts BioTissue Name Across Entire Business

TissueTech, Inc.—a pioneer in the clinical application of cryopreserved human birth tissue products to treat ocular surface disease and disorders, chronic wounds, and musculoskeletal conditions—has unveiled a corporate rebranding, including a name change and a new logo. BioTissue, Inc. and Amniox Medical, Inc. will now both be known under a single commercial, customer facing entity, BioTissue, Inc. … With three decades of continual advancements in regenerative medicine, BioTissue has been a clear leader in the ocular space. By adopting the BioTissue name across the entire organization, the company will also reflect that innovative heritage and promise in its surgical business, which was previously known as Amniox Medical … “For years, health care professionals have known our products—regardless of their specific applications—for providing mother nature’s most natural gift of healing so their patients can get back to the lives they love,” said Ted Davis, president and CEO, BioTissue. “Our new, unified brand supports our entire pipeline of human birth tissue products to aid the treatment of wounds, musculoskeletal conditions, trauma-induced injuries, ocular surface disease, and burns.” … read more

Complex multilevel and multivessel endovascular revascularization through an occluded

femoral-popliteal bypass in a patient with chronic limb threatening ischemia
Chronic limb-threatening ischemia (CLTI) represents the end stage of peripheral artery disease, a problem of growing prevalence and increased health care costs around the globe. CLTI is a highly morbid disease, incurring significant mortality, limb loss, pain, and diminished health-related quality of life. The major cause of non-traumatic lower extremity amputation are related to diabetes and CLTI. Between 2% to 3% of patients with peripheral artery disease present with a severe case of CLTI, a condition that is correlated with multilevel and multivessel arterial disease, calcification, and chronic total occlusions. Multiple technical strategies to successfully cross long occlusions in arterial segments have been described. Recanalization can be performed using endoluminal, subintimal, and retrograde techniques … read more

First Patients Enrolled in Prospective Randomized Multi-Center Comparative Clinical Study Evaluating Restrata®

for the Treatment of Venous Leg Ulcers
Acera Surgical, Inc. (Acera), a leading bioscience company developing and commercializing a portfolio of fully synthetic materials for regenerative medical applications, today announced its first patient enrollment in a multicenter, head-to-head clinical study evaluating Restrata® for the treatment of non-healing venous leg ulcers (VLUs). William Marston, M.D., the George Johnson Jr. Distinguished Professor of Vascular Surgery at the University of North Carolina School of Medicine is the study’s lead investigator. The study will be the first level 1 clinical comparison between Restrata and a biologic skin substitute.

Venous leg ulcers (VLUs) are a chronic ulcer type which affect 3% of the world population, including over 2 million people annually in the US.1,2 VLUs are a major cause of morbidity and poor quality of life resulting from venous insufficiency in the lower limbs. This type of wound presents clinical challenges as VLUs may require many months of treatment before healing is achieved.3 The US economic burden of VLU treatment was close to $15 billion in 2014 … read more

New Diabetic Foot Ulcer Guidelines Highlight Importance Of Nutrition

New guidelines endorsed by the American Limb Preservation Society highlighted the importance of nutrition in wound healing for adults with diabetes, who also experience diabetic foot ulcers (DFU) … The guidelines stated that nutritional interventions were “recommended for all patients who could benefit now or in the future from nutritional care.” As such, healthcare providers should develop and implement an individualized nutrition care plan for individuals with or at risk of a DFU, who are additionally malnourished or at risk of malnutrition … read more

New guidance highlights the importance of nutrition to support people living with diabetes and foot ulcers

A multidisciplinary team of medical professionals developed guidance for healthcare professionals outlining the importance of nutrition therapy to support wound healing for foot ulcers … The guidance provides expert consensus regarding how nutrition from arginine, glutamine, hydroxymethylbutyrate (HMB), and micronutrients can help improve wound-care therapy for people living with diabetes who are more likely to develop foot ulcers … read more

Incision care and dressing selection in surgical incisions wounds

Findings from an international meeting of surgeons from Northern Europe
Post-surgical incision care must be optimised, particularly in terms of reducing the risk of infection and associated complications (Sandy-Hodgetts et al, 2017; 2018; Morgan-Jones et al, 2019). An international consensus meeting was conducted in 2019 to examine post-surgical care and dressing selection for surgical incisions closed with primary intention (Morgan-Jones et al, 2019). A group of surgeons from Germany, Denmark, Finland and Norway convened online to discuss the findings raised in the 2019 international report and how they fit with local practice with the following aims … read more

Latest APMA Health Policy and Advocacy Wins

APMA works tirelessly to advocate for the podiatric medical profession. Over the past year, APMA has been successful in ensuring podiatrists receive equitable reimbursement, and patients have full access to care provided by podiatrists. Recent successes include:

HealthNet Federal Services (HNFS), the TRICARE administrator for the West Region, agreed to APMA’s previous request, and now permits podiatrists to order non-invasive vascular or arterial studies for TRICARE beneficiaries … read more

Evidence-Based Care in Diabetic Foot Ulcers | Video

My name is Alton Johnson. I’m a DPM, (and a) certified wound specialist as well. Currently, a clinical assistant, professor, podiatrist, pediatric surgeon, wound care specialist at the University of Michigan Hospital System – Michigan Medicine, currently working as a podiatrist and wound care specialist.

By the statement, “Not all DFUs are created equally,” (this) simply means that no one wound is ever the same when it comes to diabetic foot ulcerations. That could be applicable to all ulcerations but in general, you don’t know … watch

Practice Alert New ICD-10 Codes for MASD

In response to an initiative spearheaded by the Wound, Ostomy and Continence Nurses Society (WOCN), new diagnosis codes moisture-associated skin damage (MASD) were added to the current version of the International Classification of Disease, Clinical Modification (ICD-10-CM). These codes arc used globally to identify diseases and health conditions of patients in the United States. They are also linked to third-party payment for health care and related supplies … read more

Impact of the COVID-19 pandemic on patients with hidradenitis suppurativa

Compared to prior to the pandemic, fewer patients consulted their primary physician for changing wound dressings and more changed the dressings themselves or were assisted by their family members. 13% of patients avoided doctor visits due to fear of COVID-19 and 26.1% minimised doctor visits … The Dermatology Life Quality Index showed a moderate to very severe impact on patients’ Quality of Life (mean score = 10.06). Only one patient used telemedicine. Due to limited access to primary care and fear of COVID-19, the pandemic had a detectable impact on the hospital management of patients with HS in our facility. Telemedicine still plays a negligible role in primary wound care … read more

Watch this mama chimp treat her son’s open wound by applying insect “poultice”

In November 2019, Alessandra Mascaro was observing a community of chimpanzees in the Loango National Park in Gabon as part of her volunteer service with the Ozouga Chimpanzee Project when she noticed some unusual behavior. A chimp named Suzee was inspecting a wound on the foot of her son, Sia. Suzee suddenly caught an insect from a nearby leaf, put it into her mouth for a moment, and then pressed it to Sia’s wound.

Mascaro caught the unusual interaction on video and forwarded it to two scientists on the project: Tobias Deschner, a primatologist with the Ozouga Chimpanzee Project, and Simone Pika, a cognitive biologist at Osnabrück University. The researchers thought the interaction could be suggestive of prosocial behavior among chimpanzees and the capacity for empathy—a question of heated debate in the field—and they spent the next 15 months looking for other examples of this type of wound-treating behavior … read more

Custom-made footwear designed for indoor use increases short-term and long-term adherence

in people with diabetes at high ulcer risk
To explore changes in footwear adherence following provision of custom-made indoor footwear in people with diabetes at high risk for plantar foot ulceration and in possession of regular custom-made footwear … Adherence indoors and outdoors was assessed objectively as percentage of steps custom-made footwear was worn, at baseline (in regular custom-made footwear), and at 1 and 12 months after providing custom-made indoor footwear (in both indoor and regular footwear). Primary group: participants with low (<80%) baseline indoor adherence; secondary group: participants with high (≥80%) baseline indoor adherence. Peak plantar pressures of the indoor footwear were compared with … read more

A new look For WOCN’s Continuing Education Center (CEC)

We (WOCN) are excited to introduce our new and improved look and feel to the WOCN® Continuing Education Center (CEC). With this new look also comes some exciting additions to the site and resources for users, including:

  • New tutorial videos outlining new features of the site and how to utilize the “My Account” functions once logged into the CEC
  • More user-friendly ways to navigate the CEC:
    • The ability to easily search for content by topics of interest
    • The ability to easily search for content by content “tags”
  • A refreshed, clean look to match WOCN branding

Check out the tutorial videos below to learn more about the new CEC!
read more

Wound Care Specialization for the Advanced Practice Clinician

Nursing is a unique and varied field often described as a union between art and science. Nursing appeals to many individuals as a first or second career, and these people see the profession through different lenses. When questioned about why they want to enter the field, many students respond that they “want to help others,” “give back to society,” or “find meaning in my work.”

Many of us can recall our transition from student to entry-level nurse, whether we started on the specialized unit of our dreams or were “strongly” encouraged to start in a general setting. There comes the day when we realize that we have begun to master a clinical knowledge set we once thought impossible. If you are at this crossroads in your career … read more

CALL FOR WOUND, OSTOMY, AND CONTINENCE-RELATED PHOTOS

It is a goal of the Wound, Ostomy, and Continence Nurses SocietyTM (WOCN®) to continuously improve the educational content of the Wound Treatment Associate (WTA®) and Ostomy Care Associate (OCA®) Programs as well as the resources available to all WOCN members. Additionally, it is a goal of WOCN to work at continuous improvement in the areas of diversity, equity, and inclusion. As such, we’d like to extend an invitation to our WOC nurse colleagues to submit photographs of wounds and ostomies, specifically representing individuals of diverse skin tone. We would also invite you to submit photos related to continence-related issues, also in diverse skin tones. A wide variety of photograph examples serve to improve the education of our members and other healthcare providers by ensuring competency in wound, ostomy, and continence (WOC) assessment for all individuals. In this way, the care of all individuals with wound, ostomy, and continence care needs can be improved … read more

Frank & Lizzie Show: Episode 011, Wound Week 2022

Frank & Lizzie are excited to see you in Philadelphia for The American Professional Wound Care Association’s (APWCA) annual conference, Wound Week 2022 at the Loews Hotel February 24-27, 2022. Frank and Lizzie shared their excitement for this advanced wound care conference with THE experts from all disciplines.

Growing Evidence That Oral Antibiotics are the New IV

A recent systematic review in the American Journal of Medicine aims to challenge the dogma surrounding antibiotic therapy for certain types of infections, including osteomyelitis.1 This constitutes superb work from Wald-Dickler and coworkers, adding to the growing body of evidence that (to coin a phrase from senior author Brad Spellberg, MD) shorter may be better and oral greater than IV … Researchers set out to evaluate if current data supports long-standing tenets regarding the superiority of IV antibiotics for the full treatment course for osteomyelitis, bacteremia and infective endocarditis. Their review included 7 randomized controlled trials regarding osteomyelitis, specifically. None of the 21 total studies among all examined infections demonstrated superiority of IV-only antibiotic treatment … read more

Early Identification of Deep-Tissue Pressure Injury Using Long-Wave Infrared Thermography

A Blinded Prospective Cohort Study
The current clinical standard for diagnosing deep-tissue pressure injury (DTPI) is visual inspection. This method is subjective and only presents to the observer the external “picture;” deeper tissues are disguised from the observer. In contrast, long-wave infrared thermography (LWIT) can capture an image of the area of concern and detect tissue temperature relative to the level of tissue perfusion … To determine the efficacy of a handheld LWIT device and software solution as an adjunct to the current clinical standard of visual skin assessment to detect nonvisual pathophysiologic changes of DTPI … read more

A Case Study of Chronic Wound Management

Mr. King presented with 3 wounds located on the medial and lateral aspects of both ankles. Each wound was present for more than 3 years. In that time, he had been seen by 14 wound care physicians and another 8 podiatric and surgical specialists, in the outpatient setting. His care also included home health nursing visits for over 2 years, most commonly with daily dressing changes ordered by the many physicians trying to treat him … At 77 years old, he has many comorbidities that can impair wound healing such as; PAD, PVD, IDDM II, HDL, CKD II, HTN, Varicose Veins and uncontrolled chronic pitting edema. As a result of his wounds not healing, he was no stranger to receiving poor prognoses on the outcomes and resolution of his wounds. Because of poor choices in treatments and a lack of holistic care, more often, his wounds would get worse not better and in some cases Mr. King was told, “there’s nothing I can do, your wounds are not going to heal,” or “you’re going to lose your legs.” Most of the physicians he saw wanted to do some type of surgery or skin grafts. But Mr. King had known too many people that went in for a surgery on the leg or foot, trying to heal a wound, and ended up with an amputation … read more

Nutrition Interventions in Adults with Diabetic Foot Ulcers

Diabetic foot ulcers (DFU) are chronic wounds in the foot or feet associated with neuropathy and/or peripheral artery disease (PAD) of the lower limb in patients with diabetes mellitus. Reports from the Centers for Disease Control and Prevention show that in the United States there are nearly one in four adults living with diabetes, which indicates that a large number of Americans are at risk of DFU. DFUs will develop in up to 34% of patients with diabetes at some time in in their lives, and of those, approximately 15%–25% will require an amputation. Moderate or severe malnutrition has been identified in over half of patients with DFU, and malnutrition in DFU is correlated with increased lower-extremity amputation. Improvements in wound care therapy, including nutrition interventions, can reduce the financial burden of DFUs and increase life expectancy and quality of life … read more

To Conquer or Be Defeated: The Strategy Behind Winning the Wound Infection Battle | webinar

Wound infection has a significant impact on wound healing potential. When managing a wound, the first step is to determine if you are looking at an acute or chronic wound infection. Acute wound infection can be devastating and is often an underappreciated clinical condition that has been reported to increase the cost of care by up to 70%. Chronic wound infections are microbiologically, immunologically, and clinically distinct from acute wound infections and require a different treatment strategy … register

The significance of surface pH in chronic wounds

Wound healing is a complex, multifaceted process which is influenced by both intrinsic and extrinsic factors. The pH of the wound can affect many factors including oxygen release, angiogenesis, protease activity, and bacterial toxicity. Chronic non-healing wounds have an elevated alkaline environment. Healing occurs more readily in an acid environment. Current wound bed assessment is dependent on subjective evaluation with few diagnostic instruments available or suited to routine practice. Monitoring surface pH may provide a method of ‘measuring’ the condition of the wound bed and ultimately aid in determining the wound’s response to treatment … read more

Automating wound care in hospitals

Chronic wounds are a global medical problem closely linked to diabetes. Every year, two per cent of the US population suffers chronic wounds, many resulting in amputation because they do not heal naturally and are typically infected with antibiotic-resistant bacteria. Consequently, conventional treatment methods such as antibiotics are often not an option. However, start-up VulCur Medtech has now developed an automated laser solution writes the Technical University of Denmark in this press release … While competitors are focusing on surface treatment, VulCur MedTech’s treatment goes deeper, cleaning the wounds from the inside out using an automated laser device that kills bacteria while avoiding human cells … read more

The Wound Care Evidence Summit™

The Summit will provide a critically needed multi-disciplinary meeting for payers, government agency policymakers, prominent researchers, wound care medical specialty societies, patient and clinical associations, wound care clinics and manufacturers to address the shared goals of:

  • Addressing the current state of wound care research and clinical trial design
  • Exploring solutions to address the limitations in the wound care evidence-base
  • Communicating with payer medical directors on the development of coverage policies and the use of clinical practice guidelines in coverage decisionmaking
  • Defining “next steps” to actualize solutions
  • Participating in a uniquely intimate gathering of leading decisionmakers

register

Bio Plaster Produced from the 3D Printer Aboard the International Space Station

The long-term goal of the experiment is to cover skin wounds with bio-ink from a 3D printer like a band-aid … The new technology should help to significantly improve wound care on space missions, but also in daily medical use on Earth … Human cells from the 3D printer, with which skin wounds can be covered like an adhesive plaster – that is the long-term goal of the Bioprint FirstAid experiment. As part of the mission “Cosmic Kiss”, the German ESA astronaut Matthias Maurer has now carried out the test series on the International Space Station. The mobile hand-held device is intended to significantly improve wound care … read more

Obesity, Diabetes and Peripheral Neuropathy in Patients With Class 3 Obesity

In individuals with class 3 obesity, obesity itself may be as strong as prediabetes or type 2 diabetes (T2D) in driving the risk of peripheral neuropathy (PN), a study in the Journal of Clinical Endocrinology and Metabolism suggests.

The study analyzed plasma global metabolomics and targeted lipidomics in participants with obesity who either had PN (n=44) or didn’t have PN (n=44). These participants were matched for glycemic status and compared with a lean, non-neuropathic control participants … read more

U.S. diabetes deaths top 100,000 for second straight year

Jan 31 (Reuters) – More than 100,000 Americans died from diabetes in 2021, marking the second consecutive year for that grim milestone and spurring a call for a federal mobilization similar to the fight against HIV/AIDS.

The new figures come as an expert panel urges Congress to overhaul diabetes care and prevention, including recommendations to move beyond a reliance on medical interventions alone. A report released earlier this month calls for far broader policy changes to stem the diabetes epidemic, such as promoting consumption of healthier foods, ensuring paid maternal leave from the workplace, levying taxes on sugary drinks and expanding access to affordable housing, among other areas … read more

Steps Towards Preventing and Reducing Hypertrophic Scars: One Surgeon’s Experience

Hypertrophic scarring secondary to wound dehiscence remains an ongoing challenge for foot and ankle surgeons, despite advancements in surgical techniques and products development. Unattractive or thick scars on any patient exasperate me, but they are especially tough to endure when the patient is a child. A significant portion of my practice focuses on pediatric patients. A thick, wide, noticeable scar on this patient cohort can discourage the parents, the patient, and the doctor alike … read more

Building knowledge of wound care through competency-based education programs

Throughout Covid-19, the pandemic media has highlighted the burden it puts on healthcare systems and professionals. Providing timely and professional care to people suffering from acute and chronic wounds has been particularly difficult. There are two challenges: access to care and access to professional care. Although medical professionals are aware of the need for advanced education, it can be difficult to obtain advanced wound care education due to the increased workload and limited access to education.

A nurse specializing in wounds, ostomy, and continence in Canada (NSWOCC) works with Canadian clinicians to address the lack of access to professional wound care. NSWOCC owns and operates the WOC (Wound, Ostomy, and Continence) laboratory. The WOC-Institute is a practice and competence base of various standards to help healthcare professionals improve their wound, ostomy, and excretion skills and understanding by taking advantage of both online and direct learning opportunities. We offer the program of. The WOC-Institute’s competency-based education program is a team of knowledgeable and dedicated nurse leaders from the Canadian Association of Nurses (CNA) certified nurses specializing in wounds, osteoporosis, and excretion … read more

Glycemic Control Reduces Risk of Diabetic Foot Ulcers in Type 1 Diabetes

Early intensive glycemic control decreases the long-term risk of diabetic foot ulcers (DFUs) in patients with type 1 diabetes (T1D), according to a study in Diabetes Care … Researchers evaluated the effects of intensive treatment (INT) vs conventional treatment (CON) in patients with T1D from the Diabetes Control and Complications Trial (DCCT) on the subsequent risk of DFU and lower-extremity amputations (LEA) in the follow-up Epidemiology of Diabetes Interventions and Complications (EDIC) study … read more

Using Negative Pressure Wound Therapy With Instillation and Dwell Time to Create a Path …

to Closure for Older Patients With Chronic Wounds: A Retrospective Case Series
BACKGROUND: Chronic podiatric wounds are common causes of morbidity and mortality in older patients. Negative pressure wound therapy with instillation and dwell time (NPWTi-d) has been recommended in wounds with high levels of exudate, contaminated wounds, and wounds in which healing progression has stalled. PURPOSE: This retrospective case series describes the use of NPWTi-d to prepare 4 chronic wounds for closure in older patients with multiple comorbidities. METHODS: Patients (N = 4) ranged in age from 65 to 95 years and had wounds present for at least 90 days. Previous treatments included conventional NPWT and debridement. NPWTi-d consisted of instillation of 10 to 20 mL normal saline, dwell time for 1 minute, followed by 3-hour cycles of -125 mm Hg. Antibiotics were administered as needed. Wounds included a 210-day Wagner grade 3 diabetic foot ulcer (3.2 × 1.8 × 0.3 cm3), a 90-day dehisced wound (9.5 × 2.6 × 0.4 cm3), a 300-day neuropathic ulcer … read more

Diabetes: Know it! Fight it! Webinar

Every wound-care clinician treats diabetic patients regardless of your care point. In this course, Nancy will help you evaluate the wound, identify the best plan of treatment and steer you away from the potential setbacks for better healing rates and overall patient outcomes … register

What is the practice and understanding of podiatrists towards patient-centred consultations regarding diabetic foot care?

Background: Patient education is an integral part of diabetes management, yet research shows that increased knowledge alone does not translate into behaviour change. Behaviour change techniques (BCTs) have the potential to increase foot self-care and reduce the incidence of diabetic foot disease. Aims: The aim of this study was to explore the practice and understanding of podiatrists towards patient-centred support versus prescriptive instruction in consultations regarding diabetic foot care. Methods: The study was a cross-sectional design with a web-based questionnaire distributed to members of the College of Podiatry in the UK. Descriptive statistics, conceptual content analysis and the Pearson product-moment correlation coefficient were used to analyse the data. Results: Most respondents reported using BCTs in their consultations “often” or “very often” and that they “strongly agree” or “agree” that their consultations were patient-led, yet most were categorised as having a partial or poor understanding of these terms. Three themes emerged regarding barriers and facilitators, including ‘Skills and confidence’, ‘Patients do not want to take control … read more

Advertise on WoundCareWeekly.com

We will soon be relaunching the Wound Care Weekly newsletter to our list of 7,000 wound care and podiatry professionals. We are looking for sponsors to keep the lights on for WCW. In addition to the newsletter, sponsor exposure would include prominent website visibility (website gets close to 30,000 page views per month), Facebook header and sticky posts (FB page has 1,600 likes and followers) and LinkedIn posts (about 1,200 connections). I expect dramatic growth for web traffic from the newsletter based on activity from when it was previously active. Our latest media kit is below, let me know if you have any questions.
WCW-media_kit_2022.pdf
-Andy Durban

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The white coat: Symbol of respect, or a liability?

A doctor’s white coat is not only a staple of healthcare attire, but it’s also a symbol of professionalism, authority, kindness, and trust. While medical students know that trust is earned through practice, donning the white coat marks an important milestone in their journey to doctorhood … But the glory of this esteemed garment may dwindle when one considers the harm it could cause. Not only do white coats serve as vehicles for pathogens, but they also shine a light on patients’ perceptions of gender and professionalism, revealing gender bias in some cases … read more

Comments at HCPCS Public Meeting

The Alliance spoke at the Dec. 1-2, 2021 HCPCS Public Meeting in support of the CMS HCPCS Workgroup’s preliminary coding decision to establish three new Level II HCPCS codes for non-pneumatic compression devices. “Including disparate devices into the same HCPCS code would severely limit the ability of CMS and other interested parties to collect data and assess the utilization, cost, efficacy and clinical outcomes of these new devices. Therefore, we are in agreement with the creation of three new K codes since it will allow CMS to establish appropriate product segmentation thereby avoiding issues related to data collection and analysis,” the Alliance told the Workgroup … read more

Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 improves diabetic wound healing

Impaired keratinocyte functions are major factors that are responsible for delayed diabetic wound healing. In addition to its antimicrobial activity, the antimicrobial peptide derived from insulin-like growth factor-binding protein 5 (AMP-IBP5) activates mast cells and promotes keratinocyte and fibroblast proliferation and migration. However, its effects on diabetic wound healing remain unclear. Human keratinocytes were cultured in normal or high glucose milieus. The production of angiogenic growth factor and cell proliferation and migration were evaluated. Wounds in normal and streptozotocin-induced diabetic mice were monitored and histologically examined. We found that AMP-IBP5 rescued the high glucose-induced attenuation of proliferation and migration as well as the production of angiogenin and vascular endothelial growth factor in keratinocytes. AMP-IBP5-induced activity was mediated by the epidermal growth factor receptor … read more

Case Study – Diabetic Foot Abscess and Sepsis: Amputation or Limb Salvage?

A 48-year-old Type II insulin dependent diabetic male presented in the acute care setting with sepsis due to an abscess of the right foot involving bone and deep soft tissue structures of the midfoot. The wound and associated sepsis made limb loss and/or mortality a pressing concern. Options were primary limb amputation versus an attempt at limb salvage … read more

Classifying diabetic foot ulcers

Dermatologists must be able to distinguish between infected and noninfected diabetic foot ulcers because whether or not a DFU is infected can help determine treatment protocol, says Warrent S. Joseph, D.P.M, FIDSA.
While dermatologists are unlikely to treat patients with severe foot infections that require hospitalization, they must be able to diagnose and manage mild-to-moderate infections in diabetic foot ulcers (DFUs), and follow current Infectious Diseases Society of America (IDSA) guidelines regarding antibiotic use, according to Warren S. Joseph, D.P.M., FIDSA, who presented at DERMfoot 2018. He is a consultant, lower extremity infectious diseases, Roxborough Memorial Hospital, Philadelphia, and a co-author of the IDSA guidelines, which appeared in Clinical Infectious Diseases in June 2012 … read more

What Is the Difference Between RPM and RTM?

Ever since the CPT® 2022 codebook was released by the American Medical Association, this author has received many calls and e-mails from wound/ulcer management professionals and providers inquiring about the similarities and differences between the 5 new remote therapeutic monitoring (RTM) services codes and the 5 remote physiologic monitoring (RPM) services codes that were created in 2019. Therapists were particularly eager to learn about the new RTM codes and rules. Therefore, this author created the following table, which displays the frequently asked questions and the side-by-side comparison of the answers as they pertain to RPM and RTM … read more

Hyperbaric Oxygen Therapy in Managing Minimally Invasive Aesthetic Procedure Complications

A Report of Three Cases
Minimally invasive aesthetic procedures such as filler injections and thread lifts have gained popularity recently. Complications from these aesthetic procedures are difficult to avoid. This increasing public health concern requires a combination of effective therapeutic modalities. Hyperbaric oxygen therapy (HBOT) has generated favorable results in treating a diversity of wounds, inflammation, and infection … The cellular inflammatory cascade and wound healing process is triggered by tissue hypoxia. Maintaining an oxygen pressure of at least 30 mmHg in tissues is essential to provide an environment suitable for wound healing … The wound was clinically evaluated every 3 days. As the days progressed, the inflammation began to reside as the area of infection continued to shrink, leaving a once-blurred, now clear margin around the wound (Figure 1C). The wound fully healed within one year … read more

E-Learning and Blended-Learning Program in Wound Care for Undergraduate Nursing Students

To respond to the nursing shortage in the canton of Geneva, the School of Health Sciences increased the yearly number of Bachelor of Nursing students from 426 in 2016 to 497 in 2019 (HES-SO, 2020; 2021). In 2020, 190 students started, representing an increase of 18% since 2016. This increase had a major effect on the current face-to-face teaching methods, not only for the availability of lecturers, but also for the logistical resources. To face this problem, different virtual learning tools such as blended and e-learning were implemented. Blended learning is a combination of online learning and the traditional face-to-face learning (Siemens et al., 2015; Singh, 2003) using different technological approaches such as podcasts, lecture captures, or virtual web-based classrooms (Leidl et al., 2020), whereas e-learning is an online education method … read more

Healogics 2022 Healing Can’t Wait Program Raises Awareness about the Impact of Heart Health on Wound Healing

Healogics, the nation’s leading provider of advanced wound care services, as part of their 2022 Healing Can’t Wait program, is promoting awareness of heart health and its impact to wound healing through their seventh annual Heart Health Awareness campaign. Throughout Heart Health Awareness Month, Healogics will work to spread awareness about how cardiovascular diseases can affect the wound healing process.

An alarming 48 percent of Americans currently suffer from cardiovascular disease. Cardiovascular disease can take many forms:

  • Coronary Artery Disease (CAD)
  • Peripheral Artery Disease(PAD)
  • Vascular Insufficiency Diseases

read more

Health Equity podcast #6: Preventing diabetic foot ulcers

In this episode, we are joined by Dr. Ernest Moy, Executive Director of the Office of Health Equity and Dr. Jeffrey Robbins, director of VA Central Office Podiatry Service. Also participating is Suzanne Shirley, director of Partnerships and Community Engagement with the VA Innovation Ecosystem.

Do you know why it is so crucial to address diabetic foot ulcers?

Moy discusses differences in Veterans affected by diabetic foot ulcers and why this program to manage and reduce foot ulcers can improve the health of our Veterans.
listen

Local Tranexamic Acid Reduces Surgical Blood Loss

Tranexamic acid (TXA) is a synthetic lysine analog that reduces perioperative blood loss by blocking lysine-binding sites on plasminogen molecules. It has been reported to be effective in limiting blood loss and transfusion needs in various orthopedic surgeries and for pediatric patients at high risk of blood loss.1,2 Randomized controlled trials (RCTs) supporting the capacity of TXA to reduce blood loss and improve outcomes associated with various surgical procedures have increased fourfold in the 10 years since Evidence Corner addressed this topic, which highlighted the capacity of locally delivered TXA to reduce blood loss during … read more

The US Wound & Podiatry Registries

As part of a QCDR, the US Wound & Podiatry Registries serve many purposes:

Follow the natural history of a disease, estimate the magnitude of a problem, document the type of patients served, estimate complication rates, understand variations in outcomes, determine clinical effectiveness of treatments in the real world, understand cost-effectiveness, monitor safety, measure and improve clinical quality … read more

Prevention or Delay of Type 2 Diabetes and Associated Comorbidities: Standards of Medical Care in Diabetes—2022

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc22-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction … read more

Stop Chasing Your Tail With High-pH Product Selection | webinar

Are you unknowingly promoting a hostile wound healing environment with your choice of wound cleanser, allowing for the colonization of bacteria in the wound bed? Recent studies have shown that pH is a critical factor in the balance of wound healing, and the use of high-pH products such as sodium hypochlorite can be detrimental to healthy tissue. Furthermore, more data have recently been published to show that high-pH environments trigger metabolic responses in fungi that lead to further degradation of skin conditions or environment. High pH in the wound bed also seems to select positively for pathogens … register

The Wound Man

For years I was the only medical doctor doing inpatient wound consults in my hospital. I was continually amazed at the variety of wounds that reflected a wide gamut of human disease. Each wound was unique, and beyond the many pressure injuries and venous stasis lesions there were wounds from cancer, substance abuse, vasculitis, trauma, surgical dehiscence, and hematologic disorders … read more

The Amputation Prevention Symposium | August 17-20, 2022

Driven by a team of multidisciplinary course directors and led by Jihad A. Mustapha, MD, a pioneer in the field of interventional cardiology, AMP provides an unrivaled experience for endovascular and vascular specialists to gain knowledge on the latest advances in revascularization and explore groundbreaking techniques that will improve the future for CLI patients … The unequaled CLI education paired with the paramount interaction among faculty and attendees makes AMP an impactful, inspiring experience that you cannot miss … register

The Issue of Noncompliance in Wound Care Patients

Dealing with patients who either can’t or won’t participate in their care can be a challenge for health care providers across all settings. In wound care, this lack of participation can result in greater financial costs, diminished quality of life, and suboptimal clinical outcomes. This is part one of a two-part series on noncompliance in wound care patients. Part one addresses possible reasons for noncompliance. In part two, strategies to address these issues and increase patient participation are discussed … read more

Third-Degree Burn on the Neuropathic Lower Extremity in a Patient With Diabetes While …

Wearing a Copper–Containing Compression Sock: A Case Report
Many patients who have diabetes and peripheral neuropathy wear compression socks, which are widely available and may be purchased with a copper component. There is also a well-documented history of patients with neuropathy developing thermal burns from heat sources. Patients with diabetes are at an increased risk of complications when they sustain burns. PURPOSE: To describe a patient with diabetes and neuropathy who developed third-degree burns while wearing a copper-containing compression sock. CASE REPORT: A 68-year-old man with type 2 diabetes and peripheral neuropathy wore a copper-containing compression sock while sitting in the sun for several hours. Afterward, he noted severe blistering and was ultimately diagnosed with several areas of second- and third-degree burns. Wound treatment included sharp debridement … read more

Hospital-Acquired Pressure Injuries: Management and Risk Adjustment

Hospital-acquired pressure injuries (HAPIs) continue to occur despite our many improvement strategies. In this webinar, we will discuss the challenges we encounter in HAPI prevention and the sustaining of HAPI improvement strategies, especially during the COVID-19 pandemic. Three methods to address these challenges will be presented … register

COVID-19 Accelerates Virtual Wound Care

One of the journal’s initial goals was to keep our readers abreast of the latest developments and research in our specialty field.1 The COVID-19 pandemic has resulted in the greatest generational threat to “in-person” wound care and patient visits. We have been challenged with the need for social distancing, quarantines, lockdowns, and limited visitation to healthcare facilities. Healthcare professionals, patients, and providers have been forced to find viable alternative methods of care delivery … read more

Micro Medical Solutions receives FDA breakthrough device designation for MicroStent vascular stent

Micro Medical Solutions (MMS) recently announced that the US Food and Drug Administration (FDA) has granted breakthrough device designation for its MicroStent vascular stent. This novel technology is designed to achieve and maintain vessel patency, enhance wound treatment, and improve quality of life and blood flow in order to reduce amputation and mortality for patients with chronic limb-threatening ischaemia (CLTI) resulting from peripheral arterial disease (PAD) … read more

Venous Disease: Ulcers and So Much More

As wound care practitioners, we commonly encounter patients who are referred for evaluation and management of venous ulcers due to venous hypertension. These ulcers are the most common lesions of the lower extremities, affecting 1%-3% of the US population.1 Patient may have coexisting medical comorbidities such as cardiac failure and advanced arterial disease, which may impact the usage of compression therapy. The longstanding venous disease may be associated with additional morbidities such as pain, disability, and malignant transformation. Effective clinical outcomes require patient adherence with recommendations that involve a lifelong commitment to management. This article will serve as a generalized overview of this burdensome disease … read more

Calcipotriol Speeds Wound Healing, Lessens Itching in Small DEB Trial

Treatment with ointment containing a low dose of calcipotriol — an analog (similar compound) of vitamin D3 — helped to speed wound closure and reduce itching in people with dystrophic epidermolysis bullosa (DEB) in a clinical trial.

“While corroboration of our results by large-scaled studies is pending, our preliminary data suggest that topical low-dose calcipotriol ointment significantly reduces itch, accelerates wound healing, and can be safely implemented into the daily wound care of DEB patients,” the researchers wrote … read more

Likelihood of Hospital Admission Up During Foot Ulcer Episodes

Diabetic foot ulcer episodes are associated with an increased likelihood of all-cause inpatient admissions and death compared with periods after ulcer healing, according to a study published online Jan. 18 in Diabetes Research and Clinical Practice.

Brian J. Petersen, from Podimetrics in Somerville, Massachusetts, and colleagues examined data from the Medicare Limited Data Set from 2013 to 2019 to develop and validate an episode-of-care model for diabetic foot ulceration. Episodes of care were defined by clustering diabetic foot ulcer-related claims such that the longest time interval between consecutive claims in any cluster did not exceed a duration … read more

An electrically charged thin film patch used to promote wound healing

A team of researchers working at the University of Electronic Science and Technology of China has developed an electrically charged thin film patch for promoting faster wound healing. In their paper published in the journal Science Advances, the group describes their patch, how it works, and how well it performed when tested on rats … Humans have been looking for ways to promote faster healing of wounds for thousands of years in order to reduce both the length of time a patient experiences pain and the chances of infection. In this new effort, the researchers created an electrically charged thin film patch … read more

Building a better bandage

With a $2 million grant from NIH, MSU is working to better understand and treat chronic wounds
The National Institutes of Health has awarded Michigan State University’s Morteza Mahmoudi more than $2 million to further his team’s efforts in finding effective treatments for chronic wounds … Chronic wounds are complex injuries affecting millions worldwide that don’t heal on their own and can lead to amputation or even death. Mahmoudi said available bandaging techniques can be costly and are currently unable to overcome all of the challenges that prevent wounds from healing … read more

Non-invasive, tiny indicator changes color if the wound shows early signs of infection

The non-invasive indicator, which is around the same size as one of our fingertips, is the first of its kind. It does not make any contact with the wound but detects the beginnings of infection by sniffing the air above it.

It can be added to already existing bandages and allows infections to be detected without taking off the dressing – something which can inhibit the healing process and increase the likelihood of wound infection … read more

RevitaDerm Wound Care Gel Recalled Over Bacterial Contamination, FDA Warns

Double-check your medicine cabinet: One lot of RevitaDerm, a wound care gel, is being recalled due to bacterial contamination, per a notice posted by the Food and Drug Administration (FDA).

Blaine Labs triggered the voluntary recall after testing revealed that one bottle of RevitaDerm contained Bacillus cereus, a bacteria that could lead to “life-threatening, invasive infections,” per the FDA. No adverse events related to this recall have been reported yet … read more

New Guidelines For Addressing Nutrition Deficits In People With DFUs

Current estimates show that 37.3 million people, or 11.3 percent of the United States population, have diabetes.1 More than one-third of these patients will develop a diabetic foot ulcer (DFU) and recently published guidelines suggest that more than half of these patients have moderate or severe malnutrition.2

Recognizing the dearth of randomized controlled trials that specifically look at nutrition in people with DFUs as well as the challenges with nutrition adherence in this patient population, the authors of the new guidelines have emphasized practical screening and assessment tools, including key tips for physical exams, patient history and lab testing workups. The guidelines also provide an overview of dietary factors and nutrients, ranging from hydration and calorie intake … read more

Medical device-related pressure ulcers and the COVID-19 pandemic: from aetiology to prevention

This article describes the aetiology of medical device-related pressure ulcers (MDRPU) and the vicious cycle that leads to these (typically, hospital-acquired) injuries. In this cycle, the primary, deformation-inflicted cell damage leads to a secondary inflammatory oedema-related damage and then to tertiary ischaemic cell and tissue damage. These three damage factors act cumulatively, and, once the first deformation-inflicted massive cell death initiates in the distorted tissues, each of these factors escalates the cell death and tissue damage further, under and near the applied medical device. The primary pathophysiological factors of the COVID-19 pandemic — including the cytokine storm, hypoxia and hyper-coagulation, which are typical to seriously ill patients who require life-support (skin-contacting) medical devices — can fuel the damage spiral of pressure injury. A continuous positive airway pressure (CPAP) mask is a classic example of a commonly used medical device … read more

Integrating adjunctive therapy into practice: recognising ‘hard-to-heal’ wounds

The problem of delayed wound healing has been highlighted in several publications which has stimulated debate on variance and the need for updated care pathways. This paper demonstrates how adjunctive therapy can be added to the ‘standard care’ model, described in the National Wound Care Strategy Programme’s recommendations for lower limb wounds, to enhance outcomes for patients with ‘hard-to-heal’ lower limb wounds (NWCSP, 2020). A decision-making pathway based on published literature is described which uses wound assessment and observed response to treatment to allow the effective and targeted introduction of adjunctive therapies for ‘hard-to-heal’ wounds. This approach will allow the cost-effective introduction of new and evolving therapies, such as WoundExpress™ (Huntleigh Healthcare), which addresses the underlying problems associated with resistant lower limb oedema and … read more

Acetic Acid and Dakin’s Solution: Is Ancient Medicine Appropriate in Modern Times?

A study showed that in wound care there is an overuse of practices that lack evidence and science to support them and an underuse of approaches with evidence. The use of Dakin’s solution and acetic acid are two examples of what that study was referring to. Wound care clinicians, and especially certified wound care clinicians, have a responsibility to provide patients with wound care treatments based on science or clinical evidence. I myself am guilty of promoting practices that didn’t meet those criteria back in the early days of my career because I largely trusted the clinicians teaching me were doing the right thing. As I gained more knowledge and experience and heard some of my practices challenged by other “experts” in the industry, I began to question things … read more

Tiny dot that shows early signs of infection, invented by NI scientists

A small dot that changes colour if a patient’s wound shows early signs of infection has been invented by scientists at Queen’s University Belfast … The non-invasive indicator does not make any contact with the wound but detects the beginnings of infection by sniffing the air above it – it is the same size as a fingertip … It is the first of its kind and is predicted to bring major benefits to healthcare, especially because it can be added to already existing bandages … read more

Self-Bonded Hydrogel Forms Basis of Flexible Wound Patch

With wounds being a part of everyday life, it is important to evaluate the level of healing of individuals. This can vary due to conditions that slow down healing, such as diabetes and can be categorized into acute and chronic wounds … Acute wounds can take up to a number of months to heal; however, chronic wounds may extend to several years, with continued inflammation being a large issue … Approximately 300,000 people are hospitalized per year in the United States for acute wounds … read more

Ted Davis to Succeed Amy Tseng as President and CEO of TissueTech

TissueTech, Inc., a pioneer in the clinical application of cryopreserved human birth tissue products to treat ocular surface disease and disorders, chronic wounds, and musculoskeletal conditions, has named Ted Davis as the company’s new president and CEO. Davis—a seasoned biologics and orthopedics executive—takes the helm of an emerging company experiencing exponential growth, succeeding TissueTech founder and former CEO Amy Tseng, who retired January 3. Tseng remains a member of the company’s board of directors … TissueTech, Inc. is an emerging biotechnology company and leader in regenerative medicine using human birth tissue. TissueTech’s pioneering amniotic membrane products are processed using its proprietary CRYOTEK® cryopreservation technology, designed to retain the tissue’s structural and functional integrity. Today, TissueTech is breaking new ground with multiple Investigational New Drug clinical trials underway as the company pursues 351 biologics’ approval for products to treat patients’ unmet clinical needs. TissueTech is committed to empowering healthcare professionals with solutions to deliver optimal patient outcomes by fostering innovation through evidence-based science. Since its inception, clinicians have performed over 600,000 human implants with its products and published over 380 peer-reviewed studies supporting TissueTech’s platform technology. Learn more at https://tissuetech.com
read more

Perceptive Solutions Integrates with Epic, Joins Epic App Orchard Marketplace

WoundZoom Digital Wound Management solution now available on Epic’s App Orchard Marketplace

 

STEVENS POINT, WI – JANUARY 27, 2022 – Perceptive Solutions, Inc., developer of WoundZoom
Digital Wound Management, today announced its integration partnership with Epic and the availability of
WoundZoom in the Epic App Orchard marketplace. The purpose of this partnership is to provide a
seamless exchange of wound care data between WoundZoom and a facility’s Epic EHR system.
Perceptive Solutions joins the Epic App Orchard as a trusted integration partner so our customers can
leverage the benefits of WoundZoom while eliminating additional steps in their workflow. Data captured
using WoundZoom at the bedside, such as precise wound measurements, images, and clinical
assessments automatically sync to patients’ charts, creating a more efficient workflow and a complete
patient record in the EHR.

 

“Our innovative digital wound management solution enables clinicians to spend more time with patients
through automated charting, wound imaging and elimination of the manual measurement process. We are
excited to provide accessibility of WoundZoom to hundreds of healthcare organizations using EPIC,” said
Mark Lacerte, President of Perceptive Solutions. “The technology integration through Epic’s certification
process enables seamless and efficient data flow from our solution into Epic’s clinical charts. This enables
healthcare facilities to more efficiently share valuable wound care data between both clinical and
administrative team members within their EHR.”

 

About Perceptive Solutions
Perceptive Solutions modernizes the practice of wound care with technology-enabled systems designed to
increase clinical efficiency, improve care quality, and mitigate risk. Integrating smoothly with your EHR,
WoundZoom utilizes the latest AI and imaging technology to capture accurate wound images and
measurements from your smart device, automatically prompt and document appropriate actions, and
create a continuous, standardized clinical record across shifts, floors, and facilities. For more information,
visit https://perceptivesol.com/

 

Media Contact
Karen Guzdzial
Director of Marketing
(727) 225 7944
karen.guzdzial@woundzoom.com

Wound Care / Ulcer Debridement March 17, 2022

On March 17, 2022, APMA will host the fourth installment of its Coding Basics Webinar Series, “Wound Care / Ulcer Debridement.” Sarah Abshier, DPM; Mitchel Hilsen, DPM; and Lawrence Santi, DPM, will present.

This content is available to APMA members only. If you are a member, please log in to see the full content.

New Year’s Resolutions In Wound Care: Reflections And Looking Forward

Most of the panelists cite the COVID-19 pandemic as a common thread impacting their wound care practices last year. Kazu Suzuki, DPM, CWS shares that patients deferring care and mental stress on both patients and health care workers were dominant themes. He adds that his hospital system is over capacity and has been for months. Christine Miller, DPM, PhD, FACCWS, CWSP says that although her team routinely faces challenges due to socioeconomic issues, the pandemic led to the extra burden of staffing shortages … read more

Relationships of Changes in Physical Activity and Sedentary Behavior With Changes in Physical Fitness

and Cardiometabolic Risk Profile in Individuals With Type 2 Diabetes: The Italian Diabetes and Exercise Study 2 (IDES_2)
OBJECTIVE
In the Italian Diabetes and Exercise Study_2 (IDES_2), behavioral counseling promoted a sustained increase in physical activity (PA) volume (+3.3 MET h ⋅ week−1), moderate- to vigorous-intensity PA (MVPA) (+6.4 min ⋅ day−1), and light-intensity PA (LPA) (+0.8 h ⋅ day−1) and decrease in sedentary time (SED-time) (−0.8 h ⋅ day−1). Here, we investigated the relationships of changes in PA/SED-time with changes in physical fitness and cardiometabolic risk profile in individuals with type 2 diabetes … read more

Promoting digital, data driven wound care

By: Una Adderley
Una Adderley discusses the importance of data collection and analysis in changing practice and outcomes.
If I were a stick of rock, you would find the word ‘NURSE’ right through me (or maybe ‘community tissue viability nurse’ if there was enough room for all those letters!) So, in 2018, when I came into post as director of the National Wound Care Strategy programme (NWCSP), I saw the issue primarily through a clinical lens. I was not so cloistered that I thought wound care was just a nursing issue, but I did think that it was primarily a clinical challenge. If we could just get the clinical pathways sorted and get everyone who saw people with wounds (GPs, paramedics, podiatrists, surgeons and so on) to work in a more collaborative and coordinated way, we would solve the problem … read more

Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders

An Overview of Scientific Evidence and Understanding Their Mechanism of Action
The skin is the largest organ in the human body, composed of the epidermis and the dermis. It provides protection and acts as a barrier against external menaces like allergens, chemicals, systemic toxicity, and infectious organisms. Skin disorders like cancer, dermatitis, psoriasis, wounds, skin aging, acne, and skin infection occur frequently and can impact human life. According to a growing body of evidence, several studies have reported that natural products have the potential for treating skin disorders. Building on this information, this review provides brief information about the action of the most important in vitro and in vivo research on the use of ten selected natural products in inflammatory, neoplastic, and infectious skin disorders and their mechanisms that have been reported to date. The related studies and articles were searched from several databases, including PubMed, Google, Google Scholar, and ScienceDirect. Ten natural products that have been reported widely on skin disorders were reviewed in this study, with most showing anti-inflammatory, antioxidant, anti-microbial, and anti-cancer effects as the main therapeutic actions. Overall, most of the natural products reported in this review can reduce and suppress inflammatory markers, like tumor necrosis factor-alpha (TNF-α), scavenge reactive oxygen species (ROS), induce cancer cell death through apoptosis, and prevent bacteria, fungal, and virus infections indicating their potentials. This review also highlighted the challenges and opportunities of natural products in transdermal/topical delivery systems and their safety considerations for skin disorders. Our findings indicated that natural products might be a low-cost, well-tolerated, and safe treatment for skin diseases … read more

Robert S. Kirsner, MD, PhD,’s Wound Healing Pearls

Robert S. Kirsner, MD, PhD, discusses new and tried-and-true wound healing methods in his presentation at the Maui Derm for Dermatologists meeting.

Robert S. Kirsner, MD, PhD, chairman and Harvey Blank professor in the Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine in Miami, Florida, shares his pearls for greater efficacy in his presentation at the current Maui Derm for Dermatologists meeting held in Maui, Hawaii. His pearls included: letting evidence guide decisions, debriding the wound edge along with the wound, using microbes to improve healing, and more … read more

Guidelines and standards for comprehensive clinical diagnosis and interventional treatment for diabetic foot in China

Diabetic foot (DF) is one of the most common complications of diabetes and is associated with high morbidity, disability, lethality and low cure-rate. The clinical diagnosis and treatment of DF need to be standardized. The Chinese Diabetic Foot Cell and Interventional Therapy Technology Alliance has released six editions of guidelines and standards for clinical diagnosis and interventional treatment of DF, which filled the gap in the domestic DF treatment standard and played an important role in improving the level of diagnosis and treatment in China. In line with the latest developments in diagnosis and treatment, the Alliance, along with other 89 institutions, developed and issued the new edition based on the sixth edition to help standardize the clinical diagnosis and treatment of DF in China … read more

Covid-19 lockdown appears to have had a positive effect on diabetic foot ulcers

We conducted a prospective, observational, single-center study without modification of care. All patients followed for a DFU in the study center between 15th April 2020 and 11th May 2020 were included. The baseline assessment occurred 4 weeks after the beginning of lockdown and the follow-up visit 4 to 6 weeks after easing of lockdown. The primary analysis was based on the SINBAD classification … read more

Wound care research sponsored by the Department of Defense

Due to the need for more information about Department of Defense sponsored wound healing research, the Wound Healing Foundation initiated the writing of this article. It briefly describes the Vision, Mission and Goals of the Department of Defense Strategic Medical Research Plan. It also describes the current objectives of Department of Defense research funding and where to access this information in detail. The grant cycle, the timing of request for proposals and some of the specifics of their requirements are also mentioned. A brief discussion of budgeting and overhead is also included … read more

Role of Ultrathin Skin Graft in Early Healing of Diabetic Foot Ulcers

A Randomized Controlled Trial in Comparison With Conventional Methods
Diabetic foot ulcers (DFUs) are a global burden on health care systems. Despite the availability of various treatment modalities, many DFUs do not heal. Nonhealing wounds can lead to various complications, which add to significant morbidity in terms of the degree of moisture retained in the dressing, pain, foul order, and restriction of daily activities. A different treatment modality that can promote the wound healing process earlier (and is cost-effective, easy to use, and readily available) may be necessary to consider. Objective. The purpose of the current study was to demonstrate the efficacy of ultrathin skin grafting (UTSG) in the early healing of DFUs in terms of cost-effectiveness, reduced total number of hospital visits, and final wound outcome (ie, limb salvage rate). Materials and Methods. A randomized controlled trial was conducted in which 52 patients were treated with either UTSG … read more

The International Alliance Of Wound Care Scholarship Foundation® Announces inaugural scholarship recipients

Three rising wound care clinicians receive up to $1,500 each
KOKOMO, Ind., Jan. 25, 2022 /PRNewswire/ — The International Alliance of Wound Care Scholarship Foundation® has awarded inaugural scholarships to three recipients to commence their scholarship award program! … These scholarships are awarded to health care professionals for advanced wound care education and certification. This aids IAWCSF® in its purpose to help reduce the U.S. and global burden of wounds and associated costs by creating a larger number of providers who are educated specifically in treating wound care issues. After a thorough evaluation and assessment by the IAWCSF® Scholarship Review Board, three scholarship recipients were selected as follows … read more

 

The International Alliance of Wound Care Scholarship Foundation®

RECELL® System Data to be Presented at 44th Annual John A. Boswick Burn & Wound Care Symposium

AVITA Medical, Inc. (NASDAQ: RCEL, ASX: AVH), a regenerative medicine company that is developing and commercializing a technology platform that enables point-of-care autologous skin restoration for multiple unmet needs, announced today that six abstracts highlighting the clinical benefits of the RECELL® Autologous Cell Harvesting Device (RECELL® System) have been accepted at the 44th Annual John A. Boswick Burn & Wound Care Symposium. The international conference will be held in Maui, Hawaii, January 22-27, and covers the latest advancements in burn care, wound healing, and infection control … read more

DME for Partial Foot Amputations

The last issue of the year for Podiatry Management is typically dedicated to diabetes. Consistent with that, this article will expand on this issue’s article on PFA (partial foot amputation) written by Jeanette Smith … Devices typically used for patients with PFA range from stuffing a block of materials (toilet tissue, paper towels, rags, etc.) into the toe box of the shoe to a sophisticated hybrid lower extremity prosthetic prescribed by a physician. This article will provide some basic information on why it is important to provide the proper device … read more

Medtronic Recalls HawkOne Directional Atherectomy System

Medtronic has recalled 95,110 HawkOne Directional Atherectomy Systems because of the risk of the guidewire within the catheter moving downward or prolapsing during use, which may damage the tip of the catheter … The US Food and Drug Administration (FDA) has identified this as a Class I recall, the most serious type, because of the potential for serious injury or death … The HawkOne Directional Atherectomy system … read more

StrataGRT–A Breakthrough in Treatment on Chronic and Hard-to-Treat Wounds | video

Transcript: Hello, my name is Dr Matthew Regulski. I’m the medical director for the wound Institute of ocean County, New Jersey, and senior partner at Ocean County Foot & Ankle Surgical Associates … I want to bring to your attention today about a new fast filming, forming silicone that I think has made significant progress in the treatment of both chronic and acute wounds. I’ve been in practice for 17 years and I treat chronic wounds of all types. This has made a substantial impact on the treatment of very hard-to-heal chronic wounds … watch

Wound Management in Post-Acute Care: The Patient Journey

Friday, February 18, 2022 | 9:00AM – 4:20PM EST
Our seminar is both virtual and immersive. With a focus on applying tomorrow what you learn today, this unique experience enables you to participate in your own learning through exploration of case scenarios and interactive exercises … Effective wound prevention and management in the post-acute care setting is essential to reducing unnecessary hospital readmissions and improving patient outcomes … register

The Courage to Do the Right Thing

I was introduced to this problem early in my career. More than two decades ago, I was an Associate Professor at the University of Texas Health Science Center, Houston … Wound Center was the first of its kind (at least, that I know of) to perform “point of care” electronic documentation (in the room with the patient), using a system that internally calculated the physician’s billed level of service and collected discrete data about patients and their wounds … CMS proposed a facility billing system based on wound SIZE. That proposed system was never adopted because during a meeting with CMS, Intellicure President and CEO, David Walker, used Intellicure data from thousands of patient visits to demonstrate that, if implemented, 99% of wound center visits would be billed at the lowest level of … read more

Ouch! Assessing and Managing Acute and Chronic Wound Pain

Pain has been a prevalent health care challenge in the United States for some time, with data from the Centers for Disease Control and Prevention showing that approximately 16% of men and 20% of women experience pain on most days or even every day.1 As health care providers, we understand that unrelieved pain and suffering have direct results on the healing cascade and impair both physical and mental health. The topic of pain is almost always addressed in the health care setting, with pain even at one time being recognized as the “fifth vital sign.” … read more

Development of a prediction model for foot ulcer recurrence in people with diabetes using …

easy-to-obtain clinical variables
We used data from a prospective analysis of 304 people with foot ulcer history who had 18-month follow-up for ulcer outcome. Demographic, disease-related and organization-of-care variables were included as potential predictors. Two logistic regression prediction models were created: model 1 for all recurrent foot ulcers (n=126 events) and model 2 for recurrent plantar foot ulcers (n=70 events). We used 10-fold cross-validation, each including five multiple imputation sets for internal validation. Performance was assessed in terms of discrimination using area under the receiver operating characteristic curve (AUC) (0–1, 1=perfect discrimination), and calibration with the Brier Score (0–1, 0=complete concordance predicted vs observed values) and calibration graphs … read more

Aedicell Expands Availability of Advanced Wound Therapies to US Patients

ROCHESTER, N.Y., Jan. 24, 2022 /PRNewswire/ — To provide a growing number of patients with advanced regenerative wound therapies, Aedicell secured a Group Purchasing Agreement with Premier, Inc. making its skin substitute product Dermavest® available nationally to Premier alliance members. To accommodate the expected demand, Aedicell announces plans for a new production facility located in Cape May County, NJ, in addition to its American Association of Tissue Banks certified facility in Rochester, NY.

Premier, Inc. is a leading healthcare improvement company, uniting an alliance of more than 4,400 U.S. hospitals and health systems and approximately 225,000 other providers and organizations to transform healthcare.

“We’re here to transform the lives of people needing skin substitutes by transforming human tissue into therapies,” said Aedicell CEO Ted Burke. “This Premier Agreement will make our clinically proven therapies with enhanced patient outcomes available to more people at a lower cost, and our new facility in New Jersey will enable us to meet the expected demand for our products.” … read more

COVID-19 Proning Teams Benefit From Wound Care Specialist Nurse

The inclusion of a certified wound and skin care nurse on a multiprofessional prone-positioning team significantly reduces the odds of pressure injuries developing in patients hospitalized with severe COVID-19, according to a study published in the January issue of the American Journal of Critical Care … Connie Johnson, R.N., from Penn Medicine Princeton Health in Plainsboro, New Jersey, and colleagues evaluated the association between including a certified wound and skin care nurse on a multiprofessional pronation team and the prevention of pressure injuries … read more

Targeted nanoparticle delivery provides boost for diabetes transplant

Delivering immunosuppressant treatment via targeted nanoparticles could open the door to a long-lasting cure for type 1 diabetes. Transplanting insulin-producing cells is a promising approach to treat the disease; however, it is plagued by issues of immune rejection. In a new study, published January 17 in Nature Nanotechnology, mice treated with a reengineered therapy could tolerate a transplant for much longer with fewer side effects … For the 1.6 million people in the U.S. living with type 1 diabetes, keeping the body’s blood sugar levels within the right window at all times can be an ongoing challenge … read more

Have a slow healing wound? You need to be eating more protein.

Frustrated with a chronic wound that refuses to close? Or stay closed? It’s time you cashed in on the power of protein … Your body is programmed to heal, over and over again. Even in the face of diabetes and artery/vein diseases … So how can you speed up the body’s natural healing process? By listening to what your body is asking for. And when you have a wound, your body is craving protein … Healing the body with food isn’t about using “natural” foods on an open wound. Raw honey, apple cider vinegar, tea bags, coconut oil, and “miracle” food don’t belong on your wound. They post a huge risk of infection and moisture imbalance, which will slow healing … read more

Higher rates of all-cause mortality and resource utilization during episodes-of-care for diabetic foot ulceration

Researchers aimed at ascertaining if higher all-cause rates of mortality and resource utilization are recorded during periods of diabetic foot ulceration. In addition, an episode-of-care model for diabetic foot ulceration has been developed and validated.

  • The Medicare Limited Data Set between 2013 and 2019 was analyzed for retrieval of data for this study.
  • Episodes-of-care were defined by clustering diabetic foot ulcer linked claims such that the longest time interval between consecutive claims in any cluster did not extend beyond a duration which was adjusted to match two characteristics of foot ulcer

read more

New organic dressing invented in Oman could help wounds heal faster

A new bandage-type dressing for wounds, which has been made from plants, could be used to help them heal faster, a researcher in Oman has discovered … Saied Vakilian, a researcher at the Laboratory for Stem Cell and Regenerative Medicine at the Natural and Medical Sciences Research Centre at the University of Nizwa, led a team that used compounds made from two medicinal plants to help wounds heal faster … “This winning project aimed to evaluate a bioactive multilayer wound dressing based on chitosan and alginate,” said Vakilian … “To enhance healing potential, dracaena cinnabari and aloe vera were loaded as separate layers into the scaffold. The bare and bioactive multilayered scaffolds were fabricated by an iterative layering freeze-drying technique.” … read more

Medical Innovation And The Fight Against Amputation

Many specialists unite with one goal: preventing amputation. When podiatrists encounter patients that may lose a leg from peripheral arterial disease (PAD), vascular treatment is an urgent need. But, the question may arise: “Why doesn’t the vascular community seem to agree on how to best intervene?” … A July 2015 research paper compared the primary and secondary outcomes of angioplasty versus open vascular surgery.1 The research found both treatments equally effective in amputation prevention, improving the quality of life and life expectancy of patients with critical limb ischemia (CLI), but that endovascular treatment offered additional benefits of lower cost, lower complication rates, and easier recoveries. The study also showed a lower 30-day mortality rate for angioplasty. The article summary stated, “Based on these results it is suggested that angioplasty should be considered as the first choice for feasible CLI patients.” … read more

Response to: Remote Diabetic Foot Temperature Monitoring for Early Detection of Diabetic Foot Ulcers

A Cost-Effectiveness Analysis
We read with pleasure the recent article in your journal on the cost-effectiveness of remote diabetic foot temperature monitoring by Brooks et al.1 Diabetic foot ulcers pose a major healthcare burden, and insight into cost-effectiveness of treatments in this field is scarce, especially in preventing foot ulcers.2 Studies with original data are clearly preferred to inform clinicians, researchers and policy-makers on the potential cost-savings and health gains of preventative interventions. But modelling analyses such as by Brooks et al can provide relevant insights … For modelling analyses to be meaningful, assumptions must be based on both published evidence and clinical reasoning, and must be reasonable and logical. For a cost-effectiveness analysis on remote foot temperature monitoring, two assumptions are key … read more

BHU scientists find cure for chronic wounds. Here’s how they managed it

The team led by Prof Gopal Nath of the department of Microbiology said that wounds that took months and years to heal, could now be cured in days or months
A team of scientists from the Banaras Hindu University (BHU) have found a cure for those suffering from chronic wounds, particularly with diabetic foot ulcers. The team led by Prof Gopal Nath of the department of Microbiology, Institute of Medical Sciences, said that wounds that took months and years to heal, could now be cured in days or months. The findings of study have been published in the National Centre for Biotechnology Information, National Institutes of Health, US … read more

How TWC and Wound Clinics Will Evolve in 2022

Wound care continues to evolve as care expands beyond the wound clinic. As we move to 2022, Today’s Wound Clinic Clinical Editor Caroline E. Fife, MD, FAAFP, CWS, FUHM, and Managing Editor Brian McCurdy discuss meeting the challenges and how TWC will continue evolving in its digital format … watch video

Effectiveness of negative pressure wound therapy with instillation and dwelling after stoma closure

a retrospective and propensity score matching analysis
The use of temporary diverting stoma has become more common in low colorectal anastomosis to reduce anastomotic complications. Surgical site infection (SSI) at the stoma closure site has been one of the most frequent postoperative complications. The aim of this study was to compare the short-term outcomes between conventional primary suture closure and negative pressure wound therapy with instillation and dwelling (NPWTi-d) therapy following purse-string suturing, using propensity score matching analysis. We retrospectively evaluated the medical records of 107 patients who underwent stoma closure between January 2016 and October 2020. The primary outcome was the proportion of SSI. The secondary outcome was the day of postoperative length of stay. Propensity score matching with one-to-one match was performed for reducing treatment selection bias … read more

Survey on Wound Hygiene

An article in the Journal of Wound Care surveyed participants on awareness, implementation, barriers, and outcomes of wound hygiene.

Data from a survey created to better understand wound care awareness, implementation, barriers, and outcomes was recently published in the Journal of Wound Care. The survey, which was created by the Journal of Wound Care projects team with consultation from ConvaTech, was 26 questions long and featured a variety of multiple and open-ended questions. It was sent out by email and online, being open for a little over 12 weeks. Nonprobability sampling was used and authors of the survey reviewed the outputs to help analyze the data with the support of a medical writer … read more

Case Study – Diabetic Foot Abscess and Sepsis: Amputation or Limb Salvage?

A 48-year-old Type II insulin dependent diabetic male presented in the acute care setting with sepsis due to an abscess of the right foot involving bone and deep soft tissue structures of the midfoot. The wound and associated sepsis made limb loss and/or mortality a pressing concern. Options were primary limb amputation versus an attempt at limb salvage … In addition to his diabetes, past medical history included chronic kidney disease stage 3, sleep apnea with continuous positive airway pressure dependence, peripheral neuropathy, hyperlipidemia, hypertension, hypothyroid, morbid obesity, Moya disease, and secondary renal hyperparathyroidism … read more

EXPLAINED: Barrier Products

Barrier products, such as skin barrier films, are designed to protect the skin by minimising its exposure to excessive moisture and irritants. These may be topical preparations (available in a spray, foam applicator or wipe format) that can be applied to the skin without stinging, and dry quickly to create a breathable and transparent film. They provide a protective water-repellent barrier against irritants and harmful bodily substances, such as urine and faeces … Barrier films will not affect dressing application and are simple for both healthcare providers and patients/carers to use. Sterile products are particularly useful as they can be used on both intact and injured skin and are recommended for use in patients with a high risk of infection … read more

Wound Care Evidence Summit 2022

The Summit will provide a critically needed multi-disciplinary meeting for payers, government agency policymakers, prominent researchers, wound care medical specialty societies, patient and clinical associations, wound care clinics and manufacturers to address the shared goals of:

  • Addressing the current state of wound care research and clinical trial design
  • Exploring solutions to address the limitations in the wound care evidence-base
  • Communicating with payer medical directors on the development of coverage policies and the use of clinical practice guidelines in coverage decisionmaking
  • Defining “next steps” to actualize solutions
  • Participating in a uniquely intimate gathering of leading decisionmakers

read more

How Are Wound Clinics Coping With Omicron?

At wound clinics, physicians and staff have dealt with a lot over the past two years while the pandemic has raged. First, they were in the trenches as COVID-19 arose and hospitals were swamped, with many patients on ventilators. Even after many were vaccinated, the Delta variant caused another surge. Now, the Omicron variant is spreading quickly, with physicians facing an even more contagious version of the disease … “It still feels like the hits just keep on coming and we are not out of it yet,” says Caroline E. Fife, MD, FAAFP, CWS, FUHM. “Omicron is spreading so fast it’s mind blowing.” … The transmissibility of Omicron is a concern, as evidenced by what experts are seeing in data, according to Dr. Fife … read more

A Human Fibroblast-Derived Growth Factor Preparation in the Management of a Chronic Surgical Wound

in a Diabetic Patient: A Case Report
The surgical treatment of choice for ischaemic heart disease is Coronary Artery Bypass Grafting (CABG). The Great Saphenous Vein (GSV) is the most frequently used conduit for CABG, and the technique for harvesting the GSV entails a long open skin incision, usually comprising the entire leg. The vast proportion of patients experience leg wounds as opposed to sternal wounds. The rate of great saphenous vein harvest site infections (GSVHSI) is reported to be between 1% and 24%. Risk factors associated with GSVHSI include peripheral vascular disease, diabetes mellitus, smoking, obesity, and chronic renal failure. It is well a recognized fact that one of the most significant challenges to wound healing is infection, leading to a poor prognosis and increased morbidity.4 Hence, although rare, complications arising from the great saphenous vein harvest site may require surgical debridement leading to a delay in recovery and may negatively impact the patient … read more

Scientists Find Cure For Diabetic Foot Ulcers

Cure For Diabetic Foot Ulcers: People with diabetes, often struggle with diabetic foot ulcers, but not anymore. A team of scientists from the Banaras Hindu University (BHU) have found a cure. The findings of the study were published in the National Centre for Biotechnology Information, National Institutes of Health, US. The team led by Prof Gopal Nath of the department of Microbiology, Institute of Medical Sciences, said that wounds that took months and years to heal, could now be cured in days or months … read more

Nanoparticles Improve Immunosuppression, Could Boost Diabetes Treatment

Islet transplantation has emerged over the past few decades as a potential cure for type 1 diabetes. However, transplantation efforts have faced setbacks as the immune system continues to eventually reject new islets. Current immunosuppressive drugs offer inadequate protection for transplanted cells and tissues and are plagued by undesirable side effects … read more

Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence (DFU Biofilm)

Diabetic foot ulcers (DFU) are one of the most common reasons for hospitalization of diabetic patients and frequently results in amputation of lower limbs. Of the one million people who undergo non-traumatic leg amputations annually worldwide, 75% are performed on people who have type 2 diabetes (T2DM). The risk of death at 10 years for a diabetic with DFU is twice as high as the risk for a patient without a DFU. The rate of amputation in patients with DFU is 38.4%4. Infection is a common (>50%) complication of DFU. Emerging evidence underscores the significant risk that biofilm infection poses to the non-healing DFU. Biofilms are estimated to account for 60% of chronic wound infections. In the biofilm form, bacteria are in a dormant metabolic state. Thus, standard clinical techniques like the colony forming unit (CFU) assay to detect infection may not detect biofilm infection. Thus, biofilm infection may be viewed as a silent maleficent threat in wound care … read more

The healing of bilateral chronic VLUs using medical grade honey in an end of life patient with polymorbidity

Palliative care provides holistic, person-centred care by managing symptoms, preventing suffering by treating pain and other problems, and providing physical, psychosocial and spiritual support (Chaplin, 2004; Grocott and Gray, 2010; Dale and Emmons, 2014). Palliative wound care should focus upon relieving wound-related suffering and improving the quality of life of patients and their families when facing life-threatening illness (Grocott and Gray, 2010; Dale and Emmons, 2014). Patients requiring palliative wound care can present with any type of wound, particularly those common in older people, such as venous leg ulcers (VLUs), pressure ulcers, diabetic foot ulcers and malignant wounds … read more

New Clinical Study Finds MolecuLight i:X® Point-of-Care Imaging Improved Sensitivity

of Detecting Bacterial Burden in Surgical Site Wounds by 11-Fold

Authors Suggest that Fluorescence Imaging of Bacterial Burden is Positioned to Change
Contemporary Paradigms of Post-Surgical Wound Management

TORONTOJan. 18, 2022 /PRNewswire/ – MolecuLight Inc., the leader in point-of-care fluorescence imaging for real-time detection of wounds containing elevated bacterial loads, announced the publication of  “Uncovering the high prevalence of bacterial burden in surgical site wounds with point-of-care fluorescence imaging1 in International Wound Journal. The publication reports on the results of an analysis of 58 imaged and biopsied surgical site wounds from the 350-patient multi-centre FLAAG (fluorescence imaging assessment and guidance) clinical trial2.

Key findings of the study include:

  • 76% of surgical sites that reach the stage of referral to a wound specialist had clinically significant bacterial loads (104 to 109 CFU/g), however only 6.8% exhibited symptoms of infection, resulting in delayed infection management.
  • Point-of-care fluorescence imaging (using the MolecuLight i:X device) for detecting high bacterial loads improved sensitivity by 5.7-fold compared to clinical signs and symptoms alone.
  • Clinician experience with fluorescence imaging and interpretation (>200 imaging sessions) increased sensitivity of fluorescence imaging to 11.3-fold higher than clinical signs and symptoms alone, and accuracy to 2.6-fold higher.

The incidence of surgical wound complications, including surgical site infections (“SSI”), continue to rise and the development of an SSI is associated with a marked increase in morbidity, a 2-to 11-fold increase in mortality rate, and prolonged hospital stays3. Approximately 2-5% of surgical wounds in the US develop an SSI7-10 at an annual cost of up to $10 billion4-7. This includes extended hospital stays, readmissions, and more resources required to manage complications.

“While early identification and management of high bacterial burden is critical for the prevention of surgical site infections, this study shows that pathogenic bacterial burden is present in most (>75%) surgical wounds that are referred to a wound specialist, but is largely asymptomatic and therefore goes undetected, delaying bacterial management strategies”, says lead author Associate Professor Sandy-Hodgetts, Centre for Molecular Medicine & Innovative Therapeutics, Murdoch University & Senior Research Fellow, School of Biomedical Sciences, University of Western Australia and the Founder and inaugural President of the International Surgical Wound Complications Advisory Panel (ISWCAP). “Due to its ability to quickly and reliably detect bacterial burden at the point-of-care, fluorescence imaging using the MolecuLight device is positioned to change contemporary paradigms of post-surgical wound management”.

These findings are part of an important initiative by the International Surgical Wound Complications Advisory Panel (ISWCAP) to study surgical site infections on a global scale and highlight the need for more objective diagnostic techniques to support the early and accurate detection of clinically concerning bacterial burden in surgical wounds. The authors note that this is the first study reporting the use of an advanced diagnostic device for the visualisation and diagnosis of bacterial burden in surgical wounds.

“MolecuLight fluorescence imaging technology allows clinicians to see into the wound. The point-of-care imaging device enables clinicians to detect and manage elevated levels of bacteria to inform our decision-making,” says Dr. Thomas Serena, the publication’s contributing author, Founder and Medical Director of The SerenaGroup®, and Vice President of ISWCAP.  “Management of bacterial burden should always begin with wound hygiene strategies (e.g., cleansing, debridement), and only escalate to antibiotics when essential.”

References:

Sandy Hodgetts, K. et al., Int Wound J. 2021;1–11

2 L. Le, Advances in Wound Care, 25 Sep 2020

3Hatch MD et al. J Shoulder Elbow Surg. 2017;26(3):472-477

4 Badia JM, et al. J Hosp Infect. 2017;96(1):1-15

5 McLaws ML et al. J Hosp Infect. 2003;53(4):259-267

6 Sullivan E et al. Surg Infect (Larchmt). 2017;18(4):451-454

Ban KA et al. J Am Coll Surg. 2017;224(1):59-74

8 Berrios-Torres SI et al. JAMA Surg. 2017;152(8):784-791

9 Institute CPS. Canadian Surgical Site Infection Prevention Audit. 2016

10 Si D et al. BMC Infect Dis. 2014;14:318

 

About MolecuLight Inc.

MolecuLight Inc. is a privately-owned medical imaging company that has developed and is commercializing its proprietary fluorescent imaging platform technology in multiple clinical markets. MolecuLight’s suite of commercially released devices, including the MolecuLight i: and DX™ fluorescence imaging systems and their accessories, provide point-of-care handheld imaging devices for the global wound care market for the real-time detection of wounds containing elevated bacterial burden (when used with clinical signs and symptoms) and for digital wound measurement. The company is also commercializing its unique fluorescence imaging platform technology for other markets with globally relevant, unmet needs including food safety, consumer cosmetics and other key industrial markets.

Coverage, Payment, and the Impact of Advocacy

Decisions about which wound care products and services are (or are not) covered under Medicare are made at the national level by the CMS or regionally by Medicare contractors that each make local coverage determinations (LCDs) for the parts of the country they cover. The impact of these policies is significant. If something is not covered by Medicare, you cannot be reimbursed for it. As a result, many clinical treatment decisions are guided by Medicare coverage decisions rather than best clinical practices … read more

Utilizing Disposable, Mechanical NPWT Devices to Aid Wound Management at Home: Cost Savings Considerations

In this clinical case presentation, Dr. Napolitano describes 3 cases using mechanically powered, disposable negative pressure wound therapy. The cases covered in this presentation include an open wound after hematoma excision, Charcot foot deformity presenting with a diabetic foot ulcer, and an open wound after ankle fusion surgery. Data from this poster were presented at the SAWC Fall in Las Vegas, Nevada (October 29-31, 2021) … read more

Nutrition Interventions in Adults with Diabetic Foot Ulcers

  • Diabetic foot ulcers (DFU) are chronic wounds in the foot or feet associated with neuropathy and/or peripheral artery disease (PAD) of the lower limb in patients with diabetes mellitus.
  • Reports from the Centers for Disease Control and Prevention show that in the United States there are nearly one in four adults living with diabetes, which indicates that a large number of Americans are at risk of DFU.
  • DFUs will develop in up to 34% of patients with diabetes at some time in their lives, and of those, approximately 15%–25% will require an amputation.
  • Moderate or severe malnutrition has been identified in over half of patients with DFU, and malnutrition in DFU is correlated with increased lower-extremity amputation.

read more

Necrotizing Soft Tissue Infection of the Forearms in a Patient Using Intravenous Heroin

Case Report of Advanced Wound Management Improving Dressing Tolerance and Expediting Skin Graft
Necrotizing soft tissue infection (NSTI) is rare and characterized by rapid onset and spread of inflammation and necrosis. The infection starts within the fascia but can rapidly progress to include musculature, subcutaneous fat, and overlying skin. Its presentation is considered a surgical emergency. Persons who use intravenous or subcutaneous opioids are at higher risk of NSTIs. PURPOSE: The purpose of this case report is to describe the positive clinical outcome after consulting with wound specialists and using a dressing regimen to expedite more rapid wound healing, shortened time to skin graft, and improved pain tolerance in a patient with a history of intravenous and subcutaneous heroin use. CASE REPORT: The patient presented with an NSTI that required extensive debridement of the bilateral upper extremities. The acute surgical wound service was consulted. A dressing regimen consisting of hypochlorous acid–preserved wound cleansing, followed by carboxymethylcellulose fiber with 1.2% ionic silver covered by hydrocellular foam… read more

Diabetic Foot Surgery: An Overview

Procedures have assumed an increasingly important role in patient care
During their lifetime, up to 30% of people with diabetes will develop a foot ulcer. Diabetes-related foot ulcers and lower extremity amputations result in a major burden for patients, their family, and the healthcare system. Interest in this complex and challenging specialty has been growing and, in recent decades, there has been acceptance of a shift towards operative correction of diabetic foot deformities. Surgical management of diabetic foot deformities has now become an integral part of the overall care … read more

Maceration Mitigation: Recognition, Prevention, and Management of Overhydrated Wounds

Maceration is a common clinical complication that poses challenges in chronic wound treatment.1 Excessive moisture can be trapped on the wound surface, especially when occlusive dressings are overused or when nonbreathable cover dressings are applied for extended periods. Maceration as part of the broader umbrella of moisture-associated skin damage (MASD) occurs as a cascade of events that stem from an impaired microclimate and increased humidity on the wound’s surface. The increased moisture level causes overhydration and the stratum corneum to swell, resulting in decreased tensile strength of this epidermal layer … read more

ESVS publishes 2022 guidelines on management of chronic venous disease of the lower limb

The European Society for Vascular Surgery (ESVS) has released 2022 clinical practice guidelines on the management of chronic venous disease (CVD) of the lower limb to update its 2015 recommendations. The document, authored by Marianne G De Maeseneer (Erasmus Medical Centre, Rotterdam, The Netherlands) and colleagues, was published online ahead of print in the European Journal of Vascular and Endovascular Surgery (EJVES) … read more

New method may help make immunomodulation more effective in individuals with Type 1 diabetes

Pancreatic islets control insulin production when blood sugar levels change, and in Type 1 diabetes, the body’s immune system attacks and destroys such insulin-producing cells. Islet transplantation has emerged over the past few decades as a potential cure for Type 1 diabetes. With healthy transplanted islets, Type 1 diabetes patients may no longer need insulin injections, but transplantation efforts have faced setbacks as the immune system continues to eventually reject new islets… “At my past program, I worked on wound healing for diabetic foot ulcers, which are a complication of Type 1 diabetes,” Burke said. “As someone who’s 26, I never really want to get there, so I felt like a better strategy would be to focus on how we can treat diabetes now in a more succinct way that mimics the natural occurrences of the pancreas in a non-diabetic person.” … read more

India uses 4D bioprinting for diabetic foot ulcer management

Indian pharmaceutical firm Alkem Laboratories has announced to launch a unique patented technology for the treatment of Diabetic Foot Ulcer (DFU). The solution would be based on disruptive 4D Bioprinting technology, which would be used to treat deep, non-healing chronic wounds and is expected to be launched in the Indian market in the latter half of 2022 post regulatory approval … This advanced technology for DFU management has a high scope of preventing amputations in diabetic patients. This technology will be available at affordable rates to Indian patients at a time when there is no definitive treatment for DFU in India … read more


LinkedIn:
Alkem Laboratories

LimFlow System a ‘cost-effective and high-value alternative’ to traditional therapies

Percutaneous Deep Vein Arterialisation (pDVA) with the LimFlow System offers a cost-effective and high-value alternative to traditional therapies or amputation, according to a recent study published in the Journal of Critical Limb Ischemia … Peter Schneider, professor of surgery at the University of California (San Francisco, USA) and co-author of the published article, said: “The cost-effectiveness analysis builds on recently published 12-month data from the PROMISE I study by showing that pDVA with the LimFlow System can be a high-value therapy alternative to the status quo for no-option CLTI patients … “This research highlights the health economic benefits of reducing amputations and the need to offer patients a better alternative worldwide.” … read more


LinkedIn:
LimFlow SA

Healogics Launches Healing Can’t Wait Program For 2022

JACKSONVILLE, Fla., Jan. 13, 2022 /PRNewswire/ — Healogics®, the nation’s leading provider of world-class wound care, is announcing their “Healing Can’t Wait” program for the millions of people struggling with a non-healing wound. Chronic wounds affect seven million Americans, limiting their quality of life, as well as life expectancy … With the 2022 Healing Can’t Wait program, Healogics looks to address the significant increase in amputations observed in recent years due to the impact of COVID-19 on patient treatment schedules. It is critical that patients understand the urgency and importance of treatment. Through the 2022 Healing Can’t Wait program and resources, Healogics Wound Care Centers will focus on educating the underserved chronic wound population … “Treatment delays and the staggering increase in amputations drive us to work even harder to improve awareness and access to advanced wound care. Any untreated wound is at risk for complications such as infection, hospitalization or amputation,” explains David Bassin, Chief Executive Officer of Healogics. “This is why the Healogics Healing Can’t Wait program is so critical.” … People living with diabetes, heart disease or peripheral artery disease (PAD) are at an even greater risk for health complications that stem from an untreated wound … read more


LinkedIn:
Healogics, Inc.

Intensive glycemic control may prevent diabetic foot ulcers

medwireNews: Early intensive glycemic control may reduce the long-term risk for foot ulcers in people with type 1 diabetes, suggest data from the Diabetes Control and Complications Trial (DCCT) and Epidemiology of Diabetes Interventions and Complications (EDIC) study … The DCCT included 1408 people with type 1 diabetes who completed an average of 6.5 years of intensive (target glycated hemoglobin [HbA1c] <6.05% [42.6 mmol/mol]) or conventional (no specific glycemic target) diabetes treatment and subsequently underwent 23 years of follow-up in the EDIC study … During this period, 195 participants developed at least one diabetic foot ulcer (48 people had multiple events) and 36 needed lower extremity amputation … read more

Cryotherapy Treatment of Cutaneous Kaposi Sarcoma in a Patient With B-Cell Chronic Lymphocytic Leukemia

A Case Report and Short Review of the Literature
Kaposi sarcoma (KS) is a low-grade mesenchymal tumor involving the blood and the lymphatic vessels that primarily effaces the skin and is mediated by human herpesvirus-8 (HHV-8) in more than 90% of patients. There are 4 distinct types of KS. Compared with the classic and AIDS-related variants, chronic lymphocytic leukemia (CLL) associated with KS is a relatively rare clinical condition; thus, only a few cases have been reported. Case Report. This report presents a case study of an 87-year-old patient with B-cell CLL and cutaneous KS managed with cryotherapy, along with a short review of the literature. Conclusions. Considering that the method is relatively simple and with few adverse effects, cryotherapy may represent a simple and safe treatment method for cutaneous KS. However, more studies should be conducted … read more

Silver in Wound Care: Clinical Outcomes | webinar

Thursday, January 27, 2022

Health care professionals should consider silver nanoparticle dressings to decrease healing times and improve the quality of life of their patients.

Registrants attending this session will learn:

  • The history of silver usage
  • The problem of antimicrobial resistance
  • Indications and contraindications for the use of medicinal silver
  • Variations of medical silver in dressings and their clinical outcomes

read more

Technology in Wound Care | webinar

On Wednesday, January 19 at 8:00 PM ET, AAWC will host “Technology in Wound Care,” a webinar presented by Olamide Alabi, MD, RPVI, FACS. Dr. Alabi is an Assistant Professor of Surgery, Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Emory University School of Medicine. She was also the keynote speaker at our 2021 Pressure Ulcer Summit.

register

Kathleen D. Schaum, MS, Named World Expert in Reimbursement Health Insurance

Congratulations to TWC’s own Kathleen D. Schaum, MS, who recently received recognition as an Expertscape World Expert in Reimbursement Health Insurance.

Expertscape tweeted the news on Dec. 12 as part of International Universal Health Coverage Day. Expertscape ranks and lists the world’s top experts in Clinical and Research Medicine and calls itself “the objective, current, global resource for patients and referring physicians.” … read more

All Edema Is Lymphedema: Progressing Lymphedema and Wound Management to an Integrated Model of Care

Chronic edema affects millions of people in the United States and worldwide. Edema can result from a variety of diseases, trauma, medications, and other contributing factors; however, all edema is related to lymphatic fluid dysregulation. Additionally, lymphatic impairment and integumentary dysfunction are interrelated, leading to complex clinical presentations that require an integrated medical model of care to maximize outcomes. PURPOSE: This narrative review article will highlight the current evidence that details lymphatic physiology, fluid regulation by the endothelial glycocalyx layer, and the interconnectedness of the vascular and integumentary systems leading to a paradigm shift in our understanding of edema, lymphedema, and chronic wounds. Traditional pedagogy remains siloed with respect to the body systems, whereas current evidence indicates a certain interdependence, particularly between and among the venous, lymphatic, and integumentary systems … read more


LinkedIn:
Wound Management & Prevention

Biofilm-Innate Immune Interface: Contribution to Chronic Wound Formation

Delayed wound healing can cause significant issues for immobile and ageing individuals as well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and cancer. These delays increase a patient’s risk for infection and, in severe cases, can result in the formation of chronic, non-healing ulcers (e.g., diabetic foot ulcers, surgical site infections, pressure ulcers and venous leg ulcers). Chronic wounds are very difficult and expensive to treat and there is an urgent need to develop more effective therapeutics that restore healing processes. Sustained innate immune activation and inflammation are common features observed across most chronic wound types. However, the factors driving this activation remain incompletely understood. Emerging evidence suggests that the composition and structure of the wound microbiome may play a central role in driving this dysregulated activation but the cellular and molecular mechanisms underlying these processes require further investigation. In this review, we will discuss the current literature on: 1) how bacterial populations and biofilms contribute to chronic wound formation … read more

Maceration Mitigation: Recognition, Prevention, and Management of Overhydrated Wounds

Maceration is a common clinical complication that poses challenges in chronic wound treatment.1 Excessive moisture can be trapped on the wound surface, especially when occlusive dressings are overused or when nonbreathable cover dressings are applied for extended periods. Maceration as part of the broader umbrella of moisture-associated skin damage (MASD) occurs as a cascade of events that stem from an impaired microclimate and … read more


LinkedIn:
Alex M. Aningalan
WoundSource

Limb Loss… Who Is Really to Blame?

The Patient? The Physician? The System?—Part 1
The discipline of limb preservation and salvage has spawned extraordinary innovations in both scientific and clinical applications, offering new hope for those seeking the benefits of the burgeoning state-of-the-art lower extremity amputation prevention platforms. Wound treatment complexes are flourishing as well as access to them; research studies abound; extensive data is amassed; myriad public relations campaigns stimulate public awareness; training programs … read more

Optimising wound care through patient engagement

Patient engagement is a crucial and timely topic, both in terms of wound healing (and, in some cases, symptom management), and in improving individuals’ experiences of the process. This document aims to provide clear guidance in listening and engaging with individuals, and thus optimising the care experience for all key stakeholders, of which the patient is the most important. The document was developed with input from both healthcare professionals and individuals using healthcare services Kathleen D. Schaum … read more


LinkedIn:
Wounds International

Have You Revised Your EHR Screens/Templates and Charging System?

At the 2021 SAWC Fall a team (medical director, program director, and clinical nurse manager) from a hospital owned outpatient wound/ulcer management provider-based department (PBD) asked many questions after my main session reimbursement presentation and during my interactive reimbursement session post-conference … When I returned to my office the next week, this same team called me and requested teleconsultation services as soon as possible … As a reimbursement consultant … read more


LinkedIn:
Kathleen D. Schaum
Today’s Wound Clinic

Single cell transcriptomic landscape of diabetic foot ulcers

Diabetic foot ulceration (DFU) is a devastating complication of diabetes whose pathogenesis remains incompletely understood. Here, we profile 174,962 single cells from the foot, forearm, and peripheral blood mononuclear cells using single-cell RNA sequencing. Our analysis shows enrichment of a unique population of fibroblasts overexpressing MMP1, MMP3, MMP11, HIF1A, CHI3L1, and TNFAIP6 and increased M1 macrophage polarization in the DFU patients with healing wounds. Further, analysis of spatially separated samples from the same patient and spatial transcriptomics reveal preferential localization of these healing associated fibroblasts toward the wound bed as compared to the wound edge or unwounded skin … read more

Healthy.io achieves HITRUST CSF® certification for Information Security

BOSTON, Jan. 11, 2022 /PRNewswire/ — Healthy.io, the global leader in transforming the smartphone camera into a medical device, today announced its at-home Minuteful Kidney test and Minuteful for Wound services have earned Certified status for information security by HITRUST, which follows a standardized framework to measure HIPAA compliance … HITRUST CSF Certified status demonstrates that Healthy.io has met key federal and state regulations and industry-defined requirements and is appropriately managing risk. This achievement places Healthy.io in an elite group of organizations worldwide that has earned this certification … Healthy.io’s business case is simple: smartphone-powered technology can help health systems and insurance providers improve patient health, reduce costs across the healthcare system, and improve access to care. Early results are tremendous: In the US, health plans can more than double their current adherence rates.  A recent rollout in the United Kingdom showed that Healthy.io test kits raised test adherence from 0% to 50% among patients who had not done a urine test for kidney disease in the previous year … read more


LinkedIn:
Healthy.io

Is Your Wound Bioburdened? Case 2

• 50-year-old male with morbid obesity visiting the outpatient wound care center for bilateral lower extremity wounds and lymphedema. Click here for a photo.
• The wound on his leg was present for several months and previously treated with broad spectrum oral antibiotics for cellulitis. Click here for photo.
• Pain, odor and erythema detected from wound, prompting the clinician to perform a fluorescence scan. Click here for photo

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LinkedIn:
Today’s Wound Clinic

2021 Prime Minister’s prize for improving the repair of human tissue, a beacon for wound research in Australia

The broad purpose of laboratory-based wound research is to obtain a scientific understanding of the mechanistic processes that underpin normal and abnormal wound healing. Translation of this knowledge can lead to the development of new tools, technologies, therapeutics diagnostics and sensors that ultimately will lead to improved wound management and patient care. While this process may seem far removed from the day-to-day challenge of dealing with patients with impaired healing, occasionally we see breakthroughs and achievements that encourage both researchers and clinicians alike … read more

Effective Wound Management For Arterial Ulcers

Lower extremity ulcers are a common occurrence in individuals aged over 60. A combination of risk factors and disease processes in these individuals impact the wound healing stages, which leads to the development of chronic, non-healing ulcers. Arterial ulcers account for 8-10% of all lower extremity ulcers. However, the prevalence might be significantly underreported due to the failure to recognize the etiology of leg ulcers. Wound care specialists need to be aware of the differences between arterial ulcers and other ulcer types to provide effective wound care … read more

Wound Week 2022 – February 24-27, 2022 Philadelphia, PA

Wound Week™ 2022 is an innovative, unparalleled educational opportunity that will feature superior content delivered by multidisciplinary faculty with true clinical expertise. This conference will allow clinician driven training and education in wound care, vascular and hyperbaric medicine. In addition to education and training, this meeting will offer unmatched clinician networking … brochure (PDF)

Can Smartphone Apps Enrich Wound Care?

Access to healthcare has enhanced by leaps and bounds with the arrival of mobile technology The most interesting trends in the healthcare industry now comprise flexible and efficient wound care, among others. Extensive smartphone penetrations, along with cost-effective internet connectivity, have committed to taking wound care to the next level. Today, one can have the greatest of wound care facilities through smartphone apps. Traditionally, the healthcare industry had to offer services at dedicated wound care facilities. This required an appropriately-skilled workforce, maintenance of facilities, and important overheads, which occurred in higher costs for patients. With smartphone apps, many of these difficulties have been overcome … read more

Survey on Wound Hygiene

An article in the Journal of Wound Care surveyed participants on awareness, implementation, barriers, and outcomes of wound hygiene
Data from a survey created to better understand wound care awareness, implementation, barriers, and outcomes was recently published in the Journal of Wound Care. The survey, which was created by the Journal of Wound Care projects team with consultation from ConvaTech, was 26 questions long and featured a variety of multiple and open-ended questions. It was sent out by email and online, being open for a little over 12 weeks. Nonprobability sampling was used and authors of the survey reviewed the outputs to help analyze the data with the support of a medical writer … read more

CPD Accredited 5th International Conference on Wound Care, Tissue Repair and Regenerative Medicine

Paris, France – April 15-16, 2022

This year with the refreshing theme on “Emerging and Innovative Approaches for Wound Healing and Tissue Regeneration”.

 

Wound Care Congress is all set to bring together the eminent scholars from the wound care and tissue regeneration community presenting the unsurpassed opportunities to present and explore the future wound healing and tissue science medicine.

 

Witness the gathering the world-leading and renowned academicians, business delegates, principal investigators, nurses, homeopathists, researchers, students to witness the futuristic ideologies put forth by the experts.

 

This integrative 2-day event deliberates the new strategies, convictions that will impact the process of your professional development. Join us with your research and business tactics which will direct to the optimistic approach to the advancements of the future wound care & tissue regeneration.

 

Connect with us to Socialize, Interact, Network, and Collaborate at Wound Care Conference 2022.

 

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Embedding Predictive Analytics Into Your Wound Care Workflow | Webinar

This webinar, presented by Matt Berezo, Joshua Budman, Abbey Cooper, and Cathy Thomas Hess will discuss how wound care-specific analytics can impact a practice’s workflow. Specifically, the presenters will discuss several clinical analytics models, how they are validated, and how clinicians can use them to improve their clinical and operational outcomes … register

A systematic review of multidisciplinary teams to reduce major amputations for patients with DFUs

Multiple single-center studies have reported significant reductions in major amputations among patients with diabetic foot ulcers after initiation of multidisciplinary teams. The purpose of this study was to assess the association between multidisciplinary teams (ie, two or more types of clinicians working together) and the risk of major amputation and to compile descriptions of these diverse teams … read more

THE JWC WUWHS AWARDS ARE OPEN FOR ENTRY

The awards are ‘The Olympics of Wound Care’ and will culminate in an evening which will celebrate excellence in practicing research internally. This will be the first celebration of its kind in the UAE, recognising the fantastic work clinicians in the world and across the region have undertaken. There will be fourteen categories covering a range of wild therapy areas.

Nominations are open to individuals, teams, organisations, societies, companies, charities, and government organisations whose work has made a huge impact based on work carried out over the last year.

The deadline has been extended! You have until the 17th of January to enter … read more

Use of a purified reconstituted bilayer matrix in the management of chronic diabetic foot ulcers

improves patient outcomes vs standard of care: Results of a prospective randomized controlled multi-center clinical trial

 

The prevalence of diabetes in the United States continues to rise, with the disease now affecting 34.2 million, with an estimated additional 84 million at risk of progressing to diabetes in the coming years.1 The lifetime incidence of DFUs among diabetics is 19% to 34%, with recurrent ulceration reported as approximately 40% at 1 year and 60% at 3 years.2 Management is challenging and associated with substantial socio-economic burden approaching $40 billion annually in direct costs.3 Approximately 70% of DFUs resolve with standard wound care therapies. However, the natural healing cascade is arrested in the remaining 30%, which ultimately become chronic wounds.4, 5 Patients with chronic wounds typically suffer loss of function, recurrent infection, and significant morbidity.6 Amputations are reported in up to 20% of cases with an associated mortality of 70% at 5 years post-amputation … read more

New Level-1 Evidence Finds Geistlich Derma-Gide® Closes Significantly More Diabetic Foot Ulcers

in Appreciably Shorter Time and at Lower Costs

 

Demonstrates Superiority Compared to Standard of Care in Prospective, Randomized Controlled Trial
PRINCETON, N.J.–(BUSINESS WIRE)–The Geistlich Medical business unit of Geistlich Pharma AG, a family owned, Swiss-based global leader in regenerative solutions, is proud to announce the results from their clinical study of the Geistlich Derma-Gide® Advanced Wound Matrix. The study, “Use of a Purified Reconstituted Bilayer Matrix (PRBM) in the Management of Chronic Diabetic Foot Ulcers Improves Patient Outcomes vs Standard of Care – Results of a Prospective Randomized Controlled Multi-Center Clinical Trial,” was peer-reviewed and published in the International Wound Journal – Wiley Online Library … The paper was authored by David G. Armstrong, DPM, MD, PhD; Dennis P. Orgill, MD, PhD; Robert D. Galiano, MD; Paul M. Glat, MD; Jarrod P. Kaufman, MD; Marissa J. Carter, MA, PhD; Lawrence A. DiDomenico, DPM; and Charles M. Zelen, DPM, FACFAS. The paper is now available in the Wiley Online Library at https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.13715 … In a 40-patient, prospective, randomized, controlled multicenter clinical trial comparing a purified reconstituted bilayer matrix (PRBM, Geistlich Derma-Gide) vs. Standard of Care (SOC – collagen alginate dressing), Geistlich Derma-Gide was found to be superior relative to healing rates and time to wound closure … read more

Moisture-Associated Skin Damage | A Historic Step Forward

Every WOC nurse is aware of how often we encounter patients with conditions that are prevalent and clinically relevant but their management falls outside of available guidelines that provide direction for the care of we provide. As a result, we sometimes find ourselves managing disorders supported by scant evidence regarding epidemiology, etiology, pathophysiology, prevention, and treatment. Fortunately, WOC nurses and there are allies, along with the WOCN Society and its official journal, have a rich history of purposely drawing attention to these disorders, supporting and epidemiologic and clinical research expanding our knowledge of these conditions, and influencing public policies regulating care of these conditions … read more

What is the practice and understanding of podiatrists towards patient-centred consultations regarding diabetic foot care?

Background: Patient education is an integral part of diabetes management, yet research shows that increased knowledge alone does not translate into behaviour change. Behaviour change techniques (BCTs) have the potential to increase foot self-care and reduce the incidence of diabetic foot disease. Aims: The aim of this study was to explore the practice and understanding of podiatrists towards patient-centred support versus prescriptive instruction in consultations regarding diabetic foot care. Methods: The study was a cross-sectional design with a web-based questionnaire distributed to members of the College of Podiatry in the UK. Descriptive statistics, conceptual content analysis and the Pearson product-moment correlation coefficient were used to analyse the data. Results: Most respondents reported using BCTs in their consultations “often” or “very often” and that they “strongly agree” or “agree” that their consultations were patient-led … read more

Physician Coaching Explained

Did I choose the right path? How can I accomplish my professional goals? Do I have any career options outside of clinical practice? How can I decrease stress? I’m sure many reading this blog have asked one or more of these questions of themselves. The work we do as physicians is unique, and often many do not completely “get it,” except fellow physicians. So, whether one desires to be happier or advance in their current professional path, or seeks an entirely different trajectory, physician coaching could be a vital tool to pursue … Coaching has no definitive definition, but the concepts it entails are empowering. Thinking, listening, and verbalizing … read more

Skin Manifestations with COVID-19

The Purple Skin and Toes that you are seeing may not be Deep Tissue Pressure Injury
Many reports are occurring concerning areas of purpuric/purple skin and purple toe lesions in patients diagnosed with COVID-19 (SARS-CoV-2). Wound care providers are being asked if these skin lesions are forms of Deep Tissue Pressure Injury and/or “skin failure”. Early reports of COVID-19 related skin changes included rashes, acral areas of erythema with vesicles or pustules (pseudo-chilblain), other vesicular eruptions, urticarial lesions, maculopapular eruptions, and livedo or necrosis.1-4 The pattern and presentation of skin manifestations with COVID-19 is more than rashes … read more (PDF)

No Surprises Act – What it Means for Your Practice

Bob Jasak, VP of Coverage and Payment Policy with Hart Health Strategies will present on the recently implemented No Surprises Act and address recently released rules related to it and what it means for your practice.

This content is available to APMA members only. If you are a member, please log in to see the full content

Periwound health: new definition, new recommendations

I’m delighted to have been invited to present the best practice recommendations on the Prevention and Management of Periwound Skin Complications at this year’s Wounds UK conference (LeBlanc et al, 2020). These recommendations were devised by the International Skin Tear Advisory Panel (ISTAP) based on existing evidence and reviewed externally by 14 health professionals from seven different countries including Canada, UK, Brazil, Republic of Ireland, Switzerland, South Africa, and Indonesia. Consensus statements, of which there are 13, had to reach a level of 80% agreement to be included. The statements are summarised and discussed here for information … read more (PDF)

Custom-Molded Offloading Footwear Effectively Prevents Recurrence and Amputation …

and Lowers Mortality Rates in High-Risk Diabetic Foot Patients: A Multicenter, Prospective Observational Study
Recurrence of high-risk diabetic feet, after wound, healing is a common challenge among diabetic patients. Continuous use of an offloading device significantly prevents recurrence of high-risk diabetic feet, although patient adherence is imperative to ensuring this therapy’s clinical efficacy. In this study, we explored clinical outcomes of patients with a high-risk diabetic foot who had been prescribed with custom-molded offloading footwear under different adherence conditions … read more

Scientists map skin cells that contribute to diabetic foot ulcers

Diabetic foot ulcerations—open sores or wounds that refuse to heal—are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone. Notably, more than half of patients undergoing amputations due to diabetic foot ulcerations are expected to die within five years—a mortality rate higher than most cancers. Yet, the biological processes at work in diabetic foot ulcerations are poorly understood … read more

Wound Care Research & the Imperative for Funding

Though wound care is a robust evidence-driven field with a broad variety of treatments for chronic wounds that have been proven safe and effective, more research must be done to determine how to best optimize healing for painful, life-threatening wounds. With the anticipated rise in chronic wounds, the Federal government needs to provide more funding for wound care research so patients can get back on their feet, literally, as quickly as possible. The longer a patient suffers from a chronic wound, the more likely they are to contract potentially fatal infections … read more

Molecular Biomarkers of Oxygen Therapy in Patients with Diabetic Foot Ulcers

Alisha R. Oropallo 1,*, Thomas E. Serena 2, David G. Armstrong 3 and Mark Q. Niederauer 4
1 Comprehensive Wound Healing Center and Hyperbarics, Department of Vascular Surgery, Zucker School of Medicine Hofstra/Northwell, Hempstead, NY 11549, USA
2 Serena Group Research Foundation, Cambridge, MA 02140, USA; serena@serenagroups.com
3 Limb Preservation Program, Department of Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA; armstrong@usa.net
4 EO2 Concepts, San Antonio, TX 78249, USA; m.niederauer@eo2.com
* Correspondence: aoropallo@northwell.edu; Tel.: +1-516-233-3780

 

Hyperbaric oxygen therapy (HBOT) and topical oxygen therapy (TOT) including continuous diffuse oxygen therapy (CDOT) are often utilized to enhance wound healing in patients with diabetic foot ulcerations. High pressure pure oxygen assists in the oxygenation of hypoxic wounds to increase perfusion. Although oxygen therapy provides wound healing benefits to some patients with diabetic foot ulcers, it is currently performed from clinical examination and imaging. Data suggest that oxygen therapy promotes wound healing via angiogenesis, the creation of new blood vessels. Molecular biomarkers relating to tissue inflammation, repair, and healing have been identified. Predictive biomarkers can be used to identify patients who will most likely benefit from this specialized treatment. In diabetic foot ulcerations, specifically, certain biomarkers have been linked to factors involving angiogenesis and inflammation, two crucial aspects of wound healing. In this review, the mechanism of how oxygen works in wound healing on a physiological basis, such as cell metabolism and growth factor signaling transduction is detailed. Additionally, observable clinical … read more

Diabetes-Related Amputations Kept at Bay During Pandemic in Canada

Shift to virtual care and prioritization of certain procedures key, researchers say
Despite delays in screening and care during the COVID-19 pandemic, there wasn’t a spike in diabetes-related foot amputations, a Canadian study found … In an analysis of nearly 1.5 million adults with diabetes living in Ontario, rates for nearly all diabetes-related services took quite a nosedive in 2020, noted Charles de Mestral, MDCM, PhD, of St. Michael’s Hospital in Toronto, and colleagues … For starters, comprehensive in-person diabetes care assessment immediately dropped down from March to May, averaging only 28% of the 2019 level, they reported in JAMA Network Open … read more

Battling ‘the Pandemic within the Pandemic’

RedDress Addresses Wound Care Challenges in the COVID-19 Pandemic

Ponte Vedra Beach, FL, Jan. 05, 2022 (GLOBE NEWSWIRE) — Patients suffering with non-healing wounds continue to experience challenges accessing treatment two years after the onset of the COVID-19 pandemic … As new variants of COVID-19 emerge, wound care providers across the United States are reporting a more than 50 percent increase in the severity of wounds. If left unaddressed, these non-healing wounds can have severe consequences including infection, sepsis, amputation, and even death. RedDress is battling this compounding issue researchers have dubbed “the pandemic within the pandemic” utilizing cutting-edge technology … read more

Anastassia Johnson Tapped as Senior Manager at The Wound Pros

LOS ANGELES, Jan. 6, 2022 /PRNewswire/ — The Wound Pros (https://thewoundpros.com/) today announced Anastassia Johnson as a Senior Manager at the company. The Wound Pros specializes in the treatment and management of chronic non-healing wounds at long-term care facilities. It also partners with facilities to provide advanced wound care dressings for acute and chronic wounds as well as education for staff … Anastassia Johnson joined The Wound Pros in December 2020. She holds a Diploma and an Associate of Science Degree in Computer Systems Technology and a Bachelor of Science Degree in Information and Communication Technology. As senior manager at The Wound Pros, she brings over a decade of experience in project management, administration, customer support, quality assurance, training, and analytical decision-making … read more

Can we go from scarface to scarless?

Researchers examined skin regeneration over two years in various body parts of the adult newt, Cynops pyrrhogaster. Their wounds were very quickly healed over several days without prolonged inflammation. Because of this rapid healing, granulation/dermal fibrosis, and therefore scarring, did not occur. The skin was able to fully regenerate. These findings provide evidence that this newt species may be an ideal model system to study and prevent scar formation in human skin … read more

Newly developed injectable, adhesive surgical gel to prevent scar tissue

Up to 90% of patients who undergo open abdominal or pelvic surgery develop postoperative adhesions, or scar tissue. Minimally invasive laparoscopic surgical approaches can reduce the severity of the adhesions, but the scar tissue still forms. The cellular response to injury—even intentional injury, such as surgery to repair a problem—results in a cascade of molecules pouring to the site to heal the tissue. But the molecules, working quickly to close the wound, often go too far and bind the wound to nearby healthy tissue. Depending on the location, the resulting scar tissue can cause chronic pain, bowel obstruction and even death … read more

Wound Dehiscence After Achilles Tendon Trauma and Repair

Treatment With Ultraportable Negative Pressure Wound Therapy and Compression Therapy
Achilles tendon rupture is a common injury requiring surgical repair. Re-ruptures, infections, delayed wound healing, and hematomas have been reported postoperatively. Objective. This case series described the use of ultraportable negative pressure wound therapy (NPWT) and compression bandaging following postoperative dehiscence of Achilles tendon repair. Materials and Methods. Retrospective records were reviewed to identify patients who underwent wound management for Achilles tendon dehiscence between January 2014 and January 2018. Patient demographics, wound size at first and last visit, number of visits, and previous treatment data were extracted. Wound management included wound irrigation, surgical debridement, and application of silver dressings, as needed. Therapy was transitioned to ultraportable NPWT with twice-weekly dressing changes. When possible, patients with an ankle-brachial index greater than 0.8 received multilayer, multicomponent compression … read more

Mechanical Negative Pressure Wound Therapy: Real-World Effectiveness in Challenging Patient Presentations

When used for wound management, negative pressure wound therapy (NPWT) delivers subatmospheric pressure at the wound site, exerting multiple beneficial effects, including microstrain, macrostrain, edema management, granulation tissue formation, drainage management, and wound stabilization. Comparative effectiveness research has demonstrated similar wound healing and adverse event outcomes between traditional NPWT (tNPWT) and mechanical NPWT (mNPWT). Therefore, considerations for patient selection for mNPWT vs tNPWT are in alignment with current recommendations, including therapeutic goals, wound-related factors, patient satisfaction, quality of life, care setting, economic-related factors, and product design. Case Reports. The 3 complex patient cases in the present report describe the routine use of mNPWT between December 18, 2020, and June 7, 2021 … read more

Reflections on the Extraordinary Life of Norma N. Gill-Thompson, ET

In June 1986, I was a relatively new certified enterostomal therapy (ET) nurse. I was standing in line for an industry-sponsored lunch at my first International Association of Enterostomal Therapy (now the Wound, Ostomy, and Continence Nurses Society) meeting at Caesar’s Palace in Las Vegas, NV, when someone around me said, “Look, there’s Norma Gill!” Sure enough, she was a few spots ahead of me in line. I got so excited—it felt like I was in the presence of Florence Nightingale! I went over and introduced myself as a new ET nurse, saying how honored I was to meet her. In her down-home, humble way, she threw her arm around my shoulder and said, “Honey, come sit next to me at lunch.” So began my long and special relationship with this extraordinary pioneer of ET/wound ostomy continence … read more

INTERNATIONAL ALLIANCE OF WOUND CARE SCHOLARSHIP FOUNDATION AND HEALIANT …

Announces partnership to award wound care scholarships
The International Alliance of Wound Care Scholarship Foundation® is proud to announce a partnership with Healiant Training Solutions™ to bring hundreds of wound care scholarships to the nurse community. It is the purpose of IAWCSF® to provide financial aid in the form of scholarships to those individuals pursuing an education and certification in wound care. Healiant Training Solutions™ will match up to 100 scholarships that will be donated by sponsors from the wound care product community to be awarded to deserving healthcare providers. Accordingly, the funds will be used specifically for advanced education and subsequent certification in wound care. Our passion is wound care and our mission is to help decrease the rising costs and loss of limbs and life throughout the world. We cannot accomplish this without the help from benefactors such has Healiant. “Partnering with Healiant Training Solutions is just the beginning of what is to come for the future of wound care education and certification,” said Angela Weathersby, Ph.D., Executive Director of IAWCSF … read more

DIAGNOSTIC ACCURACY OF POINT-OF-CARE FLUORESCENCE IMAGING FOR THE DETECTION OF ….

bacterial burden in wounds

This excellent work from Le and coworkers strongly suggests that using a point of care diagnostic device (Moleculight) can identify elevated bacterial load and influence medical decision making … High bacterial load contributes to chronicity of wounds and is diagnosed based on assessment of clinical signs and symptoms (CSS) of infection, but these characteristics are poor predictors of bacterial burden. Point-of-care fluorescence imaging (FL) can improve identification of wounds with high bacterial burden (>104 CFU/g). FL detects bacteria, whether planktonic or in biofilm, but does not distinguish between the two … read more

 

The Role of Internal Offloading and Rotational Flap Closure of Charcot Arthropathy-Related Midfoot Ulcers

The patient with Charcot foot is seldom studied for their body’s ability to heal an open diabetic foot ulcer. These patients are usually excluded from all prospective randomized trials. Over a 5-year period, patients with Charcot arthropathy (CA) have been shown to have a 63% chance of developing a CA foot ulcer (CAFU), and those with a foot ulcer have a 37% mortality within the same timeframe.¹ To the authors’ knowledge, a correlation between healing a CAFU and mortality reduction has not been indicated. It is well-known that healing such ulcers improves quality of life and reduces the chance of hospitalization. The primary modality to heal such an ulcer is maintaining or creating a plantar grade foot.1 In a retrospective study of 106 patients with CAFU, Schmidt and Holmes² reported that 44% of the patients’ ulcers had healed, 11% had received a minor amputation, and only 9% had undergone major amputation … read more

Paracrine to Present at Biotech Showcase™ 2022

Paracrine, Inc. announced today that it is presenting virtually at the Biotech Showcase™ 2022 conference with an online presentation which is now accessible. This year, registered attendees to Biotech Showcase can access Paracrine’s recorded company presentation on-demand.

Paracrine is an emerging biotechnology company developing a first-in-class, device-based, autologous cell therapy. Paracrine’s cell therapy platform bears the promise of cost-effectively addressing common, underlying pathology of several debilitating chronic diseases due to its unique multi-prong mechanisms of action. The company has an FDA approved IDE for the pivotal ASCEND Trial in patients with non-healing diabetic foot ulcers, the STAR II pivotal trial IDE is currently under review at FDA for hand dysfunction due to scleroderma and an IDE is being prepared for submission later this year for the ATHENA III trial in patients with chronic heart failure … read more

Safe and effective wound healing preparation reaches Clinical Phase II

APO-2 (Aposec) is a secretome-based trial preparation derived from stressed peripheral blood mononuclear cells. APO-2 was shown to be safe and effective in a multinational Phase I study in patients with diabetic foot ulcers (non-healing foot ulcers). The Data Safety Monitoring Board has therefore recommended continuation into a Phase II clinical trial. This represents a major success for the wound healing preparation developed at MedUni Vienna … read more

The Disconnect with Diabetic Foot Ulcers | Video

During the last 10 years, the United States FDA has approved only a few new treatments for diabetic foot ulcer (DFU). Amarex’s Kazem Kazempour, PhD, believes careful study design is required to demonstrate efficacy of new wound healing treatments. In this video, Kazempour explains the disconnect between the FDA’s definition of wound healing and the reality of DFUs … watch

New Technology in Identifying Wound Infections Helping to Deprescribe Antibiotics with Martha Kelso

In this podcast, Amy Stewart, MSN, RN, DNS-MT, QCP-MT, RAC-MT, RAC-MTA, vice president of education and certification strategy for AAPACN (American Association of Post-Acute Care Nursing) and Martha Kelso, RN, LNC, HBOT, CEO of Wound Care Plus, a mobile wound care provider, discuss new point-of-care technology (MolecuLight i:X) to help identify wound infections and the impact this has on deprescribing antibiotics

Adding Wound Care Specialist to Proning Team Reduces Pressure Injury Risks

Newswise — The addition of a certified wound and skin care nurse to a multiprofessional prone-positioning team at Penn Medicine Princeton Health significantly reduced the odds of patients with COVID-19 developing pressure injuries, according to a study published in American Journal of Critical Care … The development of healthcare-associated pressure injuries is a significant complication of placing patients prone, and prolonged prone positioning for patients with acute respiratory distress syndrome (ARDS) is associated with higher rates of new pressure injuries, specifically on the face, cheekbones and thorax and over bony prominences … Although many studies have reported the development of pressure injuries in patients with ARDS who are placed prone for prolonged periods, “Pressure Injury Outcomes of a Prone-Positioning Protocol in Patients with COVID and ARDS” is one of the first to explore specific treatment-related strategies for preventing pressure injuries … read more

Prioritizing Diabetic Foot Care During Pandemic Pays Off

The COVID-19 pandemic was not associated with increased limb loss among people with diabetes in Ontario, Canada, new research suggests.

The findings, which contrast with those from several other locales worldwide, were published online January 5 in JAMA Network Open by Charles de Mestral, MDCM, PhD, of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, Toronto, Ontario, and colleagues.

Despite limited in-person visits with physicians, hospital avoidance, and non-emergency surgical procedure restrictions, excess leg amputations were not seen among people with diabetes during the first 11 months of the COVID-19 pandemic. The authors postulate several reasons for this, including prioritization of foot care … read more

UK MP highlights efforts to improve care landscape for lower limb wound patients

This country is facing a crisis in vascular disease made worse by the effects of the COVID-19 pandemic. However, there is a potential answer in the recommendations of the National Wound Care Strategy Programme, being implemented in places like Hull University Teaching Hospitals Trust, but for it to succeed it needs the full commitment and backing of government … read more

Foot Sparing Amputations in Diabetics

These techniques can save limbs and lives.
The recent global SarsCoV-2 (COVID-19) pandemic significantly disrupted the delivery of healthcare across many disciplines and the effect of the pandemic has had an especially detrimental effect on people with diabetes-related foot complications, resulting in more amputations. Major level lower extremity amputation is one of the most feared complications of diabetes. One study found that patients with diabetes and lower extremity complications were more in fear of major amputation than death.1 In many cases, major level amputations can result in loss of function, decline in quality of life, and even death … read more

Hope for Health and Healing in 2022

One year ago, this page contained a message of hope and a wish that 2021 would bring an increased appreciation for the science we desperately need.1 That wish remains as heartfelt now as it was then because the end of this pandemic remains elusive and because the millions of health care providers who have worked behind a mask to provide care deserve all the help they can get. When we think about science, our minds usually ponder new technologies, medications, or expansive, expensive, or complicated treatments or interventions. However, some of the most critical and enduring innovations to help us help patients are neither high-tech nor fancy and expensive … read more

Welcome to APWH: The Academy of Physicians in Wound Healing

APWH, the Academy of Physicians in Wound Healing, originally formed in 2011 specifically for physicians (MD,DO,DPM) now includes advanced practice providers (Nurse Practitioners-NP and Physician Assistants-PA). The organization provides information and support in three subject areas: clinical and operations-focused education, compensation advocacy, and legislative action on healthcare issues. Additionally, the organization provides this information specifically to and for the benefit of providers that are responsible for diagnosis and management of patient care which defines the demographic of our membership … read more

3D Printed Skin? Potential New Treatment For Chronic Wounds

Wounds come in many shapes and sizes. Some are small and heal quickly, causing few problems. Others are larger and slower to heal. Deep wounds that take especially long to go through the normal healing process, called chronic wounds, are of particular concern; these have a tendency to reopen and are often accompanied by infection and, eventually, scarring. Add to this the fact that chronic wounds are difficult to treat with currently available therapies, and you end up with a serious healthcare challenge … read more

Combined Regenerative Approach for a Complex Lower Extremity Wound: A Case Report

More than 400 million patients worldwide are affected by diabetes; over their lifetime, at least 25% will develop foot ulcers that often result in high rates of nonhealing wounds and amputation. The authors present the case of a 43-year-old female patient with multiple comorbidities who presented with a large (8 cm x 4 cm), noninfected, hindfoot plantar ulcer that extended down to the bone and calcaneus. Over 2 weeks, the patient was successfully treated using a combination of an acellular dermal matrix, nanofat grafting, and negative pressure wound therapy, lessening the effects of the ulcer on the patient’s quality of life and achieving limb salvage … read more

The Scientist: Robert Kirsner, MD, PhD

Dr. Kirsner is Chairman and the endowed Harvey Blank Professor in the Dr. Phillip Frost Dermatology in the Department of Dermatology and Cutaneous Surgery at the University of Miami Miller School of Medicine. He is Chief of Dermatology at the University of Miami Hospital and Clinics and Jackson Memorial Hospital and directs the University of Miami Hospital Wound Center. Dr. Kirsner received his undergraduate degree from Texas A&M University, his medical degree from the University of Miami and a PhD in epidemiology from the University of Miami, after he completed his clinical training. His clinical training included internal medicine, a clinical and research fellowship in wound healing and dermatology at the University of Miami … listen

Retrospective Analysis Using Viable Placental Membrane Allografts in Chronic Wounds

Introduction. Viable placental membrane (vPM) has been shown to decrease time to healing, adverse wound events, and wound-related infections. Wound research exclusion criteria commonly exclude wound types other than diabetic foot ulcers and venous leg ulcers (VLUs), comorbidities including peripheral arterial disease (PAD) and uncontrolled diabetes mellitus (DM), and wounds with exposed bone or tendon. Objective. This retrospective research study evaluated the clinical use and outcomes of the vPM with living mesenchymal stem cells used in chronic wound management in the community hospital outpatient department setting with the goal of comparing real-world use and outcomes of the product with use and outcomes described in the chronic wound literature … read more

Silver in Wound Care: Clinical Outcomes | Webinar

Since as early as ancient (1850 BCE) Egypt, silver has been used in wound care owing to its antimicrobial properties. Although its popularity dwindled in 1928 with the discovery of penicillin, medicinal silver has recaptured wound care professionals’ attention with the rise of antimicrobial-resistant microbes. In modern dressings, the incorporation of silver nanoparticles decreases the risk of infection while allowing the dressing to continue the facilitation of a moist wound bed environment. In nanoparticle form, silver deconstructs the cell membrane of microbes, passes into their cell body, and causes internal damage … Register

All Edema Is Lymphedema: Progressing Lymphedema and Wound Management to an Integrated Model of Care

Chronic edema affects millions of people in the United States and worldwide. Edema can result from a variety of diseases, trauma, medications, and other contributing factors; however, all edema is related to lymphatic fluid dysregulation. Additionally, lymphatic impairment and integumentary dysfunction are interrelated, leading to complex clinical presentations that require an integrated medical model of care to maximize outcomes. PURPOSE: This narrative review article will highlight the current evidence that details lymphatic physiology, fluid regulation by the endothelial glycocalyx layer, and the interconnectedness of the vascular and integumentary systems leading to a paradigm shift in our understanding of edema, lymphedema, and chronic wounds. Traditional pedagogy remains siloed with respect to the body systems, whereas current evidence indicates a certain interdependence, particularly between and among the venous, lymphatic, and integumentary systems … read more

Is Weight Loss or Physical Activity More Important for Preventing Type 2 Diabetes?

Ever since the US Diabetes Prevention Program (DPP) multicenter trial was completed nearly two decades ago (1), we have known that it is possible to prevent, or at least delay, prediabetes (an insulin–resistant state) from progressing into full-blown type 2 diabetes. Why? Diabetes risk was reduced by 58% in the “intensive lifestyle“ (ILS) participant group and by 31% in the metformin (an oral glucose-lowering medication) participants compared to no intervention (“placebo“ group). For 60 years or older participants, lifestyle changes worked much better to prevent diabetes than taking metformin … read more

Moisture Management in Neonatal Pressure Injury Prevention: A Survey

Neonates are widely known as a vulnerable patient population—especially critically ill and premature infants. This vulnerability has limited clinicians’ knowledge of moisture management products in the neonatal population that prevent pressure injuries. Recently, a survey of neonatal nurses from across the United States was conducted to find out what is being used for moisture management … This study was designed as a cross-sectional survey with a convenience sample of neonatal intensive care unit (NICU) nurses. A survey link was distributed electronically through websites, listservs, discussion boards, and newsletters to the National Association of Neonatal Nurses (NANN), the Academy of Neonatal Nurses (AAN), and WoundSource. There were 252 NICU nurses who completed the survey … read more

Cost-Effectiveness Analysis for the Treatment of Diabetic Foot Ulcer in France

Platelet-Rich Plasma vs Standard of Care
Introduction: Diabetic chronic foot ulcers (DFU) lead to pain, reduced quality of life and represent a severe economic burden for patients and health systems. The clinical results of PRP effectiveness in the treatment of DFU are promising; on the other hand, the costs associated with treating DFUs with PRP are higher than those using standard therapy. Therefore, this study aims to determine the cost-effectiveness of platelet-rich plasma (PRP) therapy compared to standard therapy from the French healthcare system perspective.
Methods: A cost-effectiveness analysis (CEA) was performed using a decision Markov model with a cohort of patients with chronic DFU (duration of > 3 weeks) with high orthopaedic risk and with ulcers graded 3A according to University of Texas classification … read more

Chronic Wounds: Innovations in Diagnostics and Therapeutics

A major global health issue is the existence of chronic wounds. Appropriate diagnosis and treatment is essential to promote wound healing and prevent further complications. Traditional methods for treatment and diagnosis of chronic wounds have shown to be of limited effectiveness. Therefore, there is a need for the development of diagnostic and therapeutic innovations in chronic wound care.

Objective: This mini-review aims to provide insight in the current knowledge of the wound healing process and the deficiencies encountered in chronic wounds, which provides a basis for the development of innovations in chronic wound care. Furthermore, promising diagnostic and therapeutic innovations will be highlighted … read more

Wound hygiene survey: awareness, implementation, barriers and outcomes

In light of the COVID-19 pandemic, which has resulted in changes to caseload management, access to training and education, and other additional pressures, a survey was developed to understand current awareness and implementation of the wound hygiene concept into practice one year on from its dissemination. Barriers to implementation and outcomes were also surveyed … read more

Prevalence of and Factors Associated with Diabetic Retinopathy in Patients with Diabetes Mellitus

at Siriraj Hospital – Thailand’s Largest National Tertiary Referral Center
Diabetic retinopathy (DR) is one of the most common chronic complications of diabetes mellitus (DM). DR is characterized by gradually progressive alterations in the retinal microvasculature, leading to areas of retinal non-perfusion, increased vascular permeability, and pathologic intraocular proliferation of retinal vessels. The complications are associated with macular edema, and uncontrolled neovascularization, termed proliferative diabetic retinopathy (PDR), resulting in severe and permanent vision loss if not treated in a timely and appropriate manner. DR is the leading cause of blindness among working-aged adults worldwide. However, with appropriate medical and ophthalmologic care, more than 90% of vision loss from PDR can be prevented.1 Unfortunately, in many cases, presenting symptoms may go unnoticed or unheeded and the damage caused by the disease becomes irreparable … By 2045, it is estimated that approximately 700 million people worldwide will have diabetes2 and that approximately 103 millions of those will have DR … read more

Theories of Skin Aging and Wound Care

Theories of Aging

One theory of aging is the free radical theory and mitochondrial DNA damage. Mitochondria are organelles within cells that are responsible for respiration, which promotes energy production using oxygen and simple sugars to produce adenosine triphosphate, the article explains. The DNA is located in a place with little protection and cannot repair itself which can lead to aging skin. The free radicals are atoms or molecules containing unpaired electrons that initiate a damaging chain reaction resulting in DNA crosslinking that leads to aging and may contribute to cancer genesis, the article continues … read more

Expanding horizons to upskill wound practice and research

With our horizons limited by Covid-related travel restrictions, it is more important than ever to experience and learn about our multicultural world through reading about wound-related research and practice in other jurisdictions and countries. Two such articles provide this important international insight and are included in this issue of the journal. The first by Obilor and colleagues describes the assessment of nurses’ knowledge, attitude and competence in wound assessment in a tertiary healthcare facility in southwest Nigeria. Here they found that many of the nurses surveyed were lacking in wound assessment competence, suggesting an important continuing need for education and skills development. The second internationally focused paper, by Yigit and Tas, describes the demography and injuries related to chemical burns in the southeastern Anatolia region of Turkey. The burn centre at the core of this study serves 10 million people in Diyarbakir and the surrounding 300km and is the only centre with an intensive care unit in southeast Turkey, a very different experience from what we would see in an Australian context … read more

AAN Updates Painful Diabetic Neuropathy Guidance

Four medication classes have been shown to help, plus topical and other treatments Gabapentinoids, serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants, and sodium channel blockers were more likely than placebo to improve diabetic neuropathy pain, according to a new practice guideline from the American Academy of Neurology (AAN). Those classes typically had comparable effect sizes…

Therapy Delayed is Therapy Denied: A Case Report of Melanoma Misdiagnosed as Diabetic Foot Ulcer

Malignant melanoma is a deadly form of skin cancer, and prompt diagnosis is a key factor in providing adequate, life-saving therapy. A 75-year-old man, with long-standing type 2 diabetes mellitus, presented with a 2- to 3-year history of right heel ulcer. He had received various therapies for a diagnosis of diabetic foot ulcer, to no avail. Physical examination showed a black, fungating ulcerated lesion on his right heel, with minimal bleeding. No inguinal lymphadenopathy was palpated. A biopsy was done, which revealed BRAF-negative malignant melanoma, with a vertical growth phase, Breslow 3.1 mm, ulceration, 11 mitoses/mm2, Clark level IV, no lymphatic or vascular invasion observed. Right inguinal lymph node sampling suggested no involvement, but PET-CT suggested pulmonary, right inguinal lymph node and bone involvement. The patient was referred to the oncologists. Written informed consent for publication was given by the patient. Diabetic foot ulcers are a frequently encountered, but serious complication of diabetes mellitus. Delayed healing is often seen, despite adequate therapy. The differential diagnosis of diabetic foot ulcers is vast and includes neoplasia. When a foot ulcer fails to heal, other differential diagnoses must be considered, in order for the patient to receive adequate therapy. Here specialist consultations, including dermatology consultations, could improve chances of delivering the right therapy promptly. This is a factor underlying the emphasis on a multidisciplinary approach to foot ulcer therapy. Our presentation – reported according to the CARE guidelines – also illustrates the fact that failure to reach a timely diagnosis may deny the patient the opportunity to receive adequate treatment … read more

Advances in Skin & Wound Care | January 2022 – Volume 35 – Issue 1

EDITORIAL


Ready, Set, Go

Advances in Skin & Wound Care. 35(1):7, January 2022.

 

PAYMENT STRATEGIES


 

PRACTICE REFLECTIONS


 

PRACTICE POINTS


Xerosis in Older Adults

Dalgleish, Lizanne; Campbell, Jill

Advances in Skin & Wound Care. 35(1):62-63, January 2022.

BIDE-NADEP-PWGDF collaborates with Ferozsons Laboratories to end avoidable foot amputations

The Country wide health initiative “Fast Track Pathway” was launched at a simple but dignified ceremony held at a local Hotel in Lahore on Dec 20, 2021 … An MOU signing ceremony was held between BIDE and Ferozsons Laboratories Limited for the implementation of this project … Addressing the ceremony, the Project Director, Dr ZahidMiyan, from Baqai Institute of Diabetology and Endocrinology, told that; Foot involvement is one of the major and devastating complications of diabetes. It is estimated that approximately 3,000,000 people with diabetes in Pakistan have foot ulcers while approximately 300,000 people loose their limbs to diabetes, every year, he told further … The huge burden of diabetic foot and the high frequency of avoidable amputations strongly necessitate consolidated and unified efforts. Dr Zahid highly appreciated the leading role of Prof Abdul Basit, the Director of BIDE, who always emphasized on nationwide improvement in diabetic foot care. In that context the “Fast Track pathway” has been launched in Pakistan, Dr Zahid declared … read more

International Alliance of Wound Care Scholarship Foundation® & Healiant™️

to award hundreds of Wound Care Scholarships
Healiant Training Solutions™ and IAWCSF® partner to make 100+ scholarships available to clinicians who desire to become wound care trained and certified.

TAMPA, FL, UNITED STATES, December 21, 2021 /EINPresswire.com/ — Healiant Training Solutions™ and the International Alliance of Wound Care Scholarship Foundation® (IAWCSF®) come together to make scholarships available to passionate clinicians who desire to become wound care trained and certified. Healiant Training Solutions™ will match up to 100 scholarships that will be donated by sponsors from the wound care product community to be awarded to deserving healthcare providers … read more

New Screening Tool to Prevent Mortality from Complications of Foot Ulcers

Individuals with diabetes have around a 34% chance of developing a diabetic foot ulcer (DFU). This debilitating condition may lead to severe complications, including hospitalization, infection, and amputation. A recent study reported grim data on DFU, finding a five-year survival rate of just 29%. Any delay in treatment has been associated with worsened clinical outcomes. The researchers of this study were interested in identifying risk factors for DFU in patients with T2D. Early detection might one day reduce the number of diabetic foot ulcers … read more

Foot ulceration associated with increased risk for amputation or death

Using the Scottish Care Information – Diabetes database, Graham Leese (Ninewells Hospital, Dundee, UK) and co-authors observed that out of 23,395 individuals with type 1 diabetes and 210,064 with type 2 diabetes included in the study, a total of 13,093 had a previous foot ulceration and among these, 34.3% developed a further foot ulcer during the follow‑up period (2012–2017). In addition, a total of 9023 people developed a first ulcer during follow-up… read more

Biomechanical and musculoskeletal changes after flexor tenotomy to reduce the risk of diabetic

neuropathic toe ulcer recurrence

OBJECTIVE: To assess the effect of flexor tenotomy in patients with diabetes on barefoot plantar pressure, toe joint angles and ulcer recurrence during patient follow-up.

METHODS: Patients with a history of ulceration on the toe apex were included. They underwent minimally-invasive needle flexor tenotomy by an experienced musculoskeletal surgeon. Dynamic barefoot plantar pressure measurements and static weight-bearing radiographs were taken before and 2-4 weeks after the procedure … read more

History of Foot Ulcer & Risk for Limb Amputation or Death

Since care for diabetic foot ulcers is delivered by a wide range of healthcare professionals, from nurses working in primary care to specialized diabetes foot clinics, collecting population-based data on diabetic foot ulceration is notoriously difficult. Furthermore, epidemiological data on populations with diabetic foot ulceration collected from selected subpopulations is open to bias, hence the importance of unselected population-based data … To address this issue, my colleagues and I conducted a national, population-based, cohort study of people with diabetes, with the aim of describing the incidence of foot ulceration and amputation-free survival associated with foot ulceration status … read more

In Vitro and In Vivo Studies on the Antibacterial Activity and Safety

of a New Antimicrobial Peptide Dermaseptin-AC

Antimicrobial resistance has been an increasing public health threat in recent years. Antimicrobial peptides are considered as potential drugs against drug-resistant bacteria because they are mainly broad-spectrum and are unlikely to cause resistance. In this study, a novel peptide was obtained from the skin secretion of Agalychnis callidryas using the “shotgun” cloning method. The amino acid sequence, molecular weight, and secondary structure of Dermaseptin-AC were determined … The skin safety of Dermaseptin-AC was evaluated on wounds on the back skin of a rat … it was applied to skin wounds. Chronic wounds are often accompanied by high bacterial burdens and, at the same time, antimicrobial resistance is more likely to occur during repeated infections and treatments. Therefore, developing Dermaseptin-AC to treat chronic wound infection may be an … read more

Technology And Innovation Power Wound Care’s Ongoing Evolution – Marketplace Experts

Like all nurses who specialize in wound care, I have seen many changes in our profession over the years. Perhaps most significant are the influences that breakthrough technologies and products have had on our profession … In order to fully appreciate its scope, we must recall recent history. Not so long ago, a non-healing diabetic foot ulcer often resulted in complications and possible amputation. In addition, to follow the healing process of a wound, the measurements had to be taken manually with rulers, a subjective measurement process that is prone to variation between institutions and even individuals … read more