and Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms Awarded NBIC Grant to Advance Development of Neem’s First-in-Class Treatments for Wound Infections
Neem Biotech, a company focused on developing novel solutions to address antimicrobial resistance, together with the Welsh Wound Innovation Centre and Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms (SCARAB) announced today the receipt of a £50,000 inaugural National Biofilms Innovation Centre (NBIC) Proof of Concept grant. This inaugural grant has been awarded to expand the development and testing of effective anti-biofilm interventions, in this case based on the pioneering research conducted by Neem Biotech. Biofilms are formed by many bacteria as a protective mechanisms for colonies of bacteria in a range of metabolic states. In humans, biofilms protect bacteria from the human immune system and antibiotics and also exude virulence factors which allow the colonies of bacteria to invade local tissues and spread infection. Products that inhibit the spread of infection in biofilms are called quorum sensing inhibitors.
Specifically, the collaborators will expand data on the biological activity of Neem’s candidate compounds for managing bacterial infections in wounds. The research is aimed at advancing rational drug design and accelerating translation of basic research into the clinic …. read more