A National Population-Based Retrospective Cohort Study
Rosemary C Chamberlain, Kelly Fleetwood, Sarah H Wild, Helen M Colhoun, Robert S Lindsay, John R Petrie, Rory J McCrimmon, Fraser Gibb, Sam Philip, Naveed Sattar, Brian Kennon, Graham P Leese
Objective: To describe incidence of foot ulceration and amputation-free survival associated with foot ulceration status in a national population-based cohort study of people with diabetes … Research design and methods: The study population included 233,459 people with diabetes who were alive in Scotland on 1 January 2012 identified from the national population-based register (national prevalence 4.9%). Characteristics of patients identified from linked hospital and mortality records during follow-up to the end of November 2017 were compared by outcome. Cox regression was used to assess the association between history of foot ulcer and amputation-free survival … Results: The population included 23,395 people with type 1 diabetes and 210,064 people with type 2 diabetes. In total there were 13,093 (5.6%) people who had a previous foot ulceration, 9,023 people who developed a first ulcer, 48,995 who died, and 2,866 … read more