Tag: diabetic neuropathy

Painful and Non-painful Diabetic Neuropathy, Diagnostic Challenges and Implications for Future Management

Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes. Up to half of patients with diabetes develop neuropathy during the course of their disease, which is accompanied by neuropathic pain in 30–40% of cases. Peripheral nerve injury in diabetes can manifest as progressive distal symmetric polyneuropathy, autonomic neuropathy, radiculo-plexopathies, and mononeuropathies.

The most common diabetic neuropathy is distal symmetric polyneuropathy, which we will refer to as DN, with its characteristic glove and stocking like presentation of distal sensory or motor function loss … read more

Inflammatory Biomarkers Levels in T2DM Emirati Patients with Diabetic Neuropathy

Previous studies have suggested the involvement of chronic low‐grade inflammation in the pathogenesis of diabetic neuropathy (DNP). However, none of these studies have examined the levels of monocyte chemoattractant protein-1 (MCP-1) in type 2 diabetes mellitus (T2DM) patients with confirmed diagnosis of neuropathy. Therefore, the present study aims to investigate the levels of MCP-1 along with IL-6, IL-8 and TGF-β in patients with T2DM and confirmed neuropathy and identify correlations, if any, between MCP-1 and other parameters … read more

Diagnosis of diabetic neuropathy using the Neurothesiometer


This educational video shows you how to perform vibration perception threshold, VPT, testing.

 

VPT testing identifies peripheral nerve dysfunction in a quantifiable manner, staging the severity of peripheral neuropathy. The VPT is tested on the pulp of the large toe. The test needs to be repeated three times and the average value is recorded. The VPT score for normal, mild, moderate and severe sensory loss is 0-14 V, 15-24 V, 25-35 V and higher than 35 V, respectively.

 

Special thanks to Prof. Rayaz Malik and Mr. Georgios Ponirakis for presenting this educational video.

 

The video was made by Mr. Oliver Smith, courtesy of Weill Cornell Medicine in Qatar.