Biomedical engineer Amit Gefen, BSc, MSc, PhD, discusses dressings in general and gelling dressings in particular from an engineering and clinical use perspective.
Amit Gefen, BSc, MSc, PhD, is a professor of biomedical engineering at Tel Aviv University and a board member of Wound Management & Prevention. His research interests include mechanobiology, tissue engineering, cell and tissue biomechanics and applications in chronic wound research … read more
Amit Gefen, Catherine T Milne, Fiona Coyer, Guido Ciprandi, Karen Ousey, Nicola Waters, Norihiko Ohura, Paulo Alves, Peter Worsley
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Although great strides have been made to tackle hospital-acquired pressure ulcers (HAPUs), there is a need for greater recognition of device-related pressure ulcers (DRPUs), including their causes, management and prevention. This consensus statement, an updated second edition, aims to continue raising awareness of these largely preventable injuries and, crucially, to stimulate action … read more
Wound dressings have been created to manage a number of clinical conditions, including cavity wounds and wounds where exudate levels may vary from low levels in a relatively dry wound to highly exuding wounds where there is a genuine risk of damage to the surrounding skin. The evidence included in this supplement highlights some of the key pre-clinical and clinical studies conducted to evaluate the performance of Exufiber and Exufiber Ag+ gelling fibre dressings … read more
This article describes the aetiology of medical device-related pressure ulcers (MDRPU) and the vicious cycle that leads to these (typically, hospital-acquired) injuries. In this cycle, the primary, deformation-inflicted cell damage leads to a secondary inflammatory oedema-related damage and then to tertiary ischaemic cell and tissue damage. These three damage factors act cumulatively, and, once the first deformation-inflicted massive cell death initiates in the distorted tissues, each of these factors escalates the cell death and tissue damage further, under and near the applied medical device. The primary pathophysiological factors of the COVID-19 pandemic — including the cytokine storm, hypoxia and hyper-coagulation, which are typical to seriously ill patients who require life-support (skin-contacting) medical devices — can fuel the damage spiral of pressure injury. A continuous positive airway pressure (CPAP) mask is a classic example of a commonly used medical device … read more