Risk Factors for *Candida auris* Colonization in Riyadh ICU Patients
A prospective observational study from a Riyadh intensive care unit (published in *Infection and Drug Resistance*, July 2025) investigates risk factors associated with *Candida auris* colonization among hospitalized adults. The research team led by Faris Altrafi and Mohammed Obeid evaluated clinical associations linked to this emerging multidrug-resistant pathogen.
Study Highlights:
- Patient Population: Over 250 adult ICU patients were screened using body site swabs to identify colonization with *C. auris*.
- Major Risk Factors: Statistical analysis found prior broad-spectrum antibiotic use, central venous catheter presence, mechanical ventilation, and diabetes mellitus were significant independent predictors of colonization.
- Colonization Rates: Approximately 13% of screened patients tested positive for *C. auris* colonization at one or more body sites.
- Clinical Implications: Colonized patients faced higher risks of subsequent bloodstream infections and associated morbidity. The authors emphasized the need for early detection protocols and strict infection control measures in ICU settings.
Conclusion: This study supports targeted surveillance for *C. auris* using risk-based screening in ICU patients, combined with robust antimicrobial stewardship and infection prevention strategies to curb its spread.
Keywords:
Faris Altrafi,
Mohammed Obeid,
Candida auris,
ICU colonization,
broad-spectrum antibiotics,
central venous catheter,
mechanical ventilation,
infection control