TIMERS: the race against hard to heal wounds

TIMERS: The Race Against Hard-to-Heal Wounds — Advanced Therapies & Patient-Related Factors

In Part 4 (Sections 5 and 6) of the “TIMERS: The Race Against Hard-to-Heal Wounds” series, *Wound Care Professional* Consultant Editor **Menna Lloyd Jones** explores the advanced and adjunctive product options alongside the critical impact of patient-related factors in wound management.

Advanced & Adjunctive Product Use — When and How:

  • Adjunctive therapies such as amniotic membranes, ECM scaffolds, platelet-rich plasma, bioengineered skin substitutes, negative pressure wound therapy (NPWT), oxygen therapy, stem cell treatments, and autologous skin grafts can be deployed to enhance repair and regeneration.
  • Ancillary options like chemical debriders (e.g., Santyl®, Octenidine), larval therapy, and activated carbon dressings serve purposes such as biofilm removal, odor control, and non-traumatic debridement.
  • Choice of advanced therapies must account for wound condition, infection status, cost, patient readiness, and realistic goals, ideally in the setting of multidisciplinary care.

Managing Patient-Related (Social) Factors:

  • The “S” component in TIMERS addresses social circumstances—such as patient literacy, belief systems, psychosocial status, adherence, and support networks—that profoundly influence outcomes.
  • Effective wound care requires patient engagement, tailored education, motivational interviewing, goal setting, and active listening to align care with individual life contexts.
  • Understanding and addressing these factors creates a strong foundation for healing and significantly improves the success of advanced therapies.

Conclusion: Integrating advanced wound therapies with a robust strategy for managing social and patient-related determinants under the TIMERS framework enables truly holistic, patient-centered wound management—especially vital in complex or recalcitrant cases.

Keywords:
Menna Lloyd Jones,
TIMERS framework,
advanced therapies,
adjunctive products,
patient-related factors,
holistic wound care,
debridement

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