Health-Related Quality of Life in Patients Receiving Venous Leg Ulcer Treatment with Compression Therapy
A randomized clinical trial published in *Wound Practice and Research* (2025) explored how different compression treatments affect the health-related quality of life (HRQoL) of patients with venous leg ulcers (VLUs) in Brazil.
Study Details:
- Study Design: 56 patients from 22 primary healthcare services were randomly assigned to receive either high-compression bandages (Group A) or Unna’s boots (Group B).
- Measurement Tool: HRQoL was assessed using the multidimensional Health State Short Form questionnaire at baseline and upon wound healing or at 26 weeks.
- Results for All Participants: Group A improved by 0.093 ± 0.09 (p < 0.001); Group B improved by 0.06 ± 0.1 (p = 0.007); no significant difference between groups (p = 0.218). :contentReference[oaicite:1]{index=1}
- Healed Ulcers: Group A: +0.109 ± 0.084 (p < 0.001); Group B: +0.113 ± 0.115 (p < 0.01); no between-group difference (p = 0.914). :contentReference[oaicite:2]{index=2}
- Unhealed Ulcers: Group A: +0.058 ± 0.098 (p = 0.09); Group B: +0.028 ± 0.078 (p = 0.182); no significant difference (p = 0.441). :contentReference[oaicite:3]{index=3}
Conclusion: Both high-compression bandages and Unna’s boots significantly improved HRQoL in patients with venous leg ulcers, with no notable difference between the two. :contentReference[oaicite:4]{index=4}
Keywords: Ana Cláudia Fuhrmann, Fernanda Peixoto Cordova, Fatima Al Sayah, Jeffrey A Johnson, Lisiane Manganelli Girardi Paskulin, venous leg ulcer, health-related quality of life, compression therapy, primary health care