Wound Progression and Healing in Patients With Moisture-Associated Skin Damage

Wound Progression and Healing in Patients With Moisture-Associated Skin Damage

A retrospective observational study published in the Journal of Wound, Ostomy, and Continence Nursing (July 2025) examined the relationship between moisture-associated skin damage (MASD) and wound healing outcomes. The research team, led by Laura R. Sibbald, investigated how MASD affects wound progression in patients receiving care at a Canadian community hospital system.

Study Highlights:

  • Patient Cohort: The study analyzed 236 patients with MASD and 236 matched controls without MASD using electronic medical records.
  • Wound Progression: Patients with MASD were more likely to experience delayed wound healing and wound deterioration compared to those without MASD.
  • Contributing Factors: Increased moisture from incontinence, sweat, and wound exudate was associated with worsening skin integrity and inflammation, leading to prolonged healing timelines.
  • Clinical Implications: The findings highlight the importance of early identification and management of MASD as a risk factor for poor wound healing outcomes in vulnerable populations.

Conclusion: MASD significantly impairs wound healing and increases the risk of wound progression. Clinical strategies focused on moisture control and barrier protection are essential to prevent complications and support recovery.

Keywords: Laura R. Sibbald, moisture-associated skin damage, wound healing, wound progression, MASD, skin integrity

Read the full study in JWOCN