Antimicrobial Activity of Jatropha curcas Latex Against Cutaneous Wound and Burn Infections
A recent study published in Infection and Drug Resistance explores the potential of Jatropha curcas latex as a topical antimicrobial for wound and burn care. The research team, led by Ali Salman Al‑Shami and Mokhtar Alzomor, investigated the plant’s latex against several antibiotic-resistant pathogens commonly implicated in skin infections.
Key Highlights:
- Pathogens Tested: The study targeted Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans.
- Results: J. curcas latex demonstrated significant antimicrobial activity, producing inhibition zones as large as 31 mm for S. aureus and showing promising minimum inhibitory concentration (MIC) values ranging from 6.25 to 25 mg/mL.
- Comparative Effectiveness: In many cases, the latex outperformed standard antibiotics like tetracycline and ofloxacin, suggesting potential as a natural alternative or adjunct therapy.
- Mechanism: The latex contains bioactive compounds such as flavonoids, saponins, and tannins, which may contribute to its antimicrobial properties.
Conclusion: The authors conclude that Jatropha curcas latex holds promise as a broad-spectrum topical agent, especially in regions facing antibiotic resistance. Further in vivo research is needed to establish clinical safety and efficacy.
Keywords:
Ali Salman Al‑Shami,
Mokhtar Alzomor,
Jatropha curcas,
burn infections,
natural antimicrobials,
antibiotic resistance,
wound healing