Expediting Acute Wound Healing via Multimodal Therapy: A Case Series
A prospective case series published in *Wound Management & Prevention* (Dec 2024) by Gallagher et al. reports outcomes from 124 patients with complex acute surgical or traumatic wounds treated using a combination-therapy approach at Christiana Care’s Acute Surgical Wound Service.
Key Highlights:
- Patient & Wound Spectrum: 124 adult patients with diverse acute wounds (up to 1120 cm³) treated from admission through healing.
- Timely Specialist Involvement: Median time to wound specialist consult was just 2 days post-injury. :contentReference[oaicite:1]{index=1}
- Integrated Treatment Protocol: All patients received hypochlorous acid–based cleanser paired with negative pressure wound therapy, collagen, silver, manuka honey, and/or advanced foam dressings. :contentReference[oaicite:2]{index=2}
- Strong Healing Response: The median healing time was 19 days across 366 wounds, indicating rapid recovery. :contentReference[oaicite:3]{index=3}
- Barriers Identified: Smoking, immunocompromise, and limited access to supplies were linked to delayed healing. :contentReference[oaicite:4]{index=4}
This mixed-modality strategy—with prompt wound specialist intervention and targeted therapeutics—substantially decreased healing time, reduced healthcare visits, and improved resource use, suggesting a scalable model for acute wound services.
Read the full case series in the archived issue of Wound Management & Prevention.
Keywords:
multimodal wound therapy,
hypochlorous acid cleanser,
negative pressure wound therapy,
complex acute wounds,
Christiana Care