Research Roundup: Advanced Therapies for Chronic Wounds
The February 2025 issue of *Wound Care Professional* highlights three significant studies evaluating advanced biological and scaffold therapies for non-healing wounds.
Key Highlights:
- Hypothermically Stored Amniotic Membrane (HSAM) for DFUs: A multicenter retrospective series (50 patients, mean age 66.7) treated diabetic foot ulcers with HSAM and observed >60% wound area reduction in 96%, and 78% complete closure by 12 weeks (median time: 55 days).
- Dehydrated Human Amnion/Chorion Membrane (DHACM) in Venous Leg Ulcers: A cost-effectiveness analysis demonstrated that DHACM is both effective and economical for treating VLUs in Medicare populations.
- 3D Acellular Collagen Matrix in Deep/Tunnelling DFUs: Retrospective case series showed promising tissue fill and wound contraction results using collagen scaffold in complex diabetic foot ulcers.
These findings reinforce the potential of amniotic and collagen-derived biological scaffolds to enhance healing in persistent chronic wounds, while also addressing cost considerations in clinical practice.
Access the full *Research Roundup* in the Wound Care Professional (Vol 4 Issue 1, Feb 2025).
Keywords:
hypothermic amniotic membrane,
dehydrated amnion/chorion membrane,
3D collagen matrix,
diabetic foot ulcer,
venous leg ulcer