Human Keratin Matrix Accelerates Healing of Venous Leg Ulcers: A Case Series
A recent case series published in the Journal of Wound Care explores the efficacy of a novel human keratin matrix (HKM) in conjunction with standard of care (SoC) for treating venous leg ulcers (VLUs). Conducted by Dr. George Koullias and Dr. Allison N. Ramey-Ward, the study assesses the healing outcomes of VLUs treated with HKM alongside indicated vascular interventions and conventional wound care practices.
Key Highlights:
- Significant Reduction in Wound Size: Very large VLUs (>200 cm²) exhibited an average size reduction of 71% within 10 weeks, achieving a 50% reduction within four HKM applications. :contentReference[oaicite:7]{index=7}
- Rapid Healing in Smaller Ulcers: Smaller VLUs (<35 cm²) reduced by 50% in size within the first three weeks of treatment, with 88.9% achieving complete healing after an average of 4.5 HKM applications over 6.5 weeks. :contentReference[oaicite:10]{index=10}
- Enhanced Healing Rates: The integration of HKM with SoC demonstrated accelerated healing compared to SoC alone, suggesting HKM’s potential to improve outcomes in hard-to-heal VLUs.
The study underscores the potential of human keratin matrices as a valuable adjunct in the management of chronic VLUs, offering promising results in both large and small ulcerations. By facilitating faster wound closure, HKM may contribute to improved patient quality of life and reduced healthcare burdens associated with prolonged wound care.
Read the full article on the Journal of Wound Care website.
Keywords:
human keratin matrix,
venous leg ulcers,
wound healing,
George Koullias,
Allison N Ramey-Ward