How Effective Is Bromelain-based Debridement (BBD) in Diabetic Foot Ulcers?
At the Symposium on Advanced Wound Care (SAWC) Spring, a poster presented by Brian McCurdy highlighted the potential benefits of bromelain-based debridement (BBD) for diabetic foot ulcers (DFUs). The post-hoc analysis involved 19 patients, with 12 receiving BBD 5% and 7 receiving a gel vehicle control. Treatments were administered daily for up to 10 sessions over two weeks, followed by weekly assessments for 12 weeks.
Key Findings:
- Complete Debridement: Achieved in 58% of BBD patients compared to 14% in the control group within the two-week treatment period.
- Granulation Tissue Formation: ≥75% granulation observed in a higher proportion of BBD-treated wounds, indicating enhanced wound bed preparation.
- Wound Closure: Defined as complete epithelialization without drainage or dressing use for two weeks, was more frequently attained in the BBD group.
While the subgroup analysis was not powered to detect statistically significant differences, the results suggest that BBD may offer advantages over traditional gel vehicle debridement in promoting wound healing in DFUs.
Read the full article on the HMP Global Learning Network website.
Keywords:
Bromelain-based debridement,
Diabetic foot ulcers,
Wound healing,
Enzymatic debridement,
Brian McCurdy