WRAHPS: New Guidelines Aim to Standardize Preclinical Wound Research
In an effort to enhance the quality and reproducibility of preclinical wound healing studies, a consortium of experts has introduced the Wound Reporting in Animal and Human Preclinical Studies (WRAHPS) guidelines. Published in the January-February 2025 issue of Wound Repair and Regeneration, these guidelines provide comprehensive checklists and reporting templates for commonly used animal and human ex vivo wound models.
Key Highlights:
- Standardization of Reporting: WRAHPS offers detailed checklists to ensure consistent documentation of experimental conditions, facilitating transparency and comparability across studies.
- Enhancing Translational Research: By addressing the variability in preclinical models and methodologies, the guidelines aim to bridge the gap between laboratory findings and clinical applications.
- Comprehensive Coverage: The guidelines encompass various aspects of preclinical studies, including animal species selection, wound induction methods, assessment techniques, and data analysis protocols.
The development of WRAHPS involved collaboration among researchers from institutions such as the University of Miami, University of Pennsylvania, The Ohio State University, and the University of Illinois Chicago. The initiative underscores the importance of meticulous reporting in advancing wound care research and ultimately improving patient outcomes.
Read the full article on the PubMed Central website.
Keywords:
Preclinical wound models,
WRAHPS guidelines,
Standardized reporting,
Translational research,
Animal models in wound healing,
Human ex vivo models