Bromelain-Based Debridement Versus Collagenase Ointment Debridement of Venous Leg Ulcers: Post Hoc Analysis of the ChronEx Trial
A recent post hoc analysis of the ChronEx trial, published in Wounds, compared the efficacy of bromelain-based enzymatic debridement (BBD) with collagenase ointment (CO) in treating venous leg ulcers (VLUs). The study aimed to assess which method more effectively achieved complete debridement and granulation within a two-week period.
The analysis included 46 patients with VLUs who were treated with either BBD or CO. Results indicated that a higher proportion of wounds treated with BBD achieved complete debridement and granulation at two weeks compared to those treated with CO. Additionally, the median time to complete debridement and granulation was shorter in the BBD group, suggesting a more rapid wound healing process.
These findings suggest that BBD may offer a more efficient alternative to CO for enzymatic debridement in VLUs, potentially leading to faster wound healing and improved patient outcomes.
Read the full article on the Wounds Journal website.
Keywords:
Bromelain-based debridement,
Collagenase ointment,
Enzymatic debridement,
Venous leg ulcer,
ChronEx trial,
Wound healing
Note: The above synopsis is based on the article’s content and available information. For a comprehensive understanding, please refer to the full article.