John W Frew – Staff Specialist Dermatologist, Liverpool Hospital, Sydney, NSW, Australia
This edition of WPR presents manuscripts from the dermatology field pertaining to conditions such as Pyoderma gangrenousm, Necrobiosis lipoidica and Hidradenitis suppurativa. Each of these conditions are characterised by aberrations in cutaneous healing relevant to the mechanistic understanding of chronic wounds, and in which ongoing translational research is identifying mechanistic pathways and novel therapeutic targets – some of which have already reached the clinic.
While the nuances of molecular pathways may seem irrelevant to the practising clinician, the identification and implementation of novel therapies for inflammatory skin disease and wounds can only be achieved through the translation (and validation) of molecular and immunological discoveries in the clinical setting … read more