in Diabetic Foot Ulcer Rats via Activating PI3K/AKT Pathway and hTERT
Diabetes is a widespread metabolic problem in modern society. Due to long-term hyperglycemia, diabetes can cause damage to multiple systems, such as the eyes, kidneys, nerves, blood vessels, etc.1 As one of the serious complications of diabetes, diabetic foot is a chronic progressive disease caused by vascular occlusive disease, which can lead to complications.2 Once foot ulcers occur, the extremities of diabetic patients are very likely to be infected with invasive infection, leading to an increased risk of amputation.3 With the annual increase in the number of diabetic patients in the world, the incidence of diabetic foot ulcer (DFU) is also increasing, which has a great impact on family, society, and economic development. There is an urgent need to develop more effective detection and treatment methods for DFU … read more