How Might Protein Alteration From NPWT Affect Wound Healing?

Excellent continued efforts in elucidating the role that perturbation of the wound matrix (via negative pressure wound therapy (NPWT)) has on angiogenesis, healing and regeneration. A recent study in Molecular Medicine Reports used label‑free quantitative mass spectrometry to analyze differences in granulation tissue protein expression profiles before and after NPWT for patients with diabetic foot ulcers (DFUs).1 They aimed to take a closer look at how NPWT promotes DFU healing. As such, the study identified multiple novel proteins altered by NPWT, paving the way for future studies in this area … read more

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